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"Designed as an easy-to-use and comprehensive reference for the practicing pathologist, Diagnostic pathology: blood and bone marrow is the newest title in the Diagnostic pathology series by Amirsys. This extensively illustrated book showcases over 1,900 high-quality images, including gross pathology and a variety of pathology stains. Included are several images that display specialized immunophenotypic and molecular genetic features of bone marrow disorders. As readers have come to expect from Amirsys reference tools, the content is presented in concise, bulleted text that quickly gets to the most critical diagnostic data, including a variety of differential diagnoses. This book pinpoints important elements in the diagnosis of benign and neoplastic disorders and it clearly delineates numerous genetic disorders often found in blood and bone marrow. Diagnostic athology: blood and bone marrow is set to become a valuable reference resource for the busy pathologist"--Provided by publisher.
This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.
Already a standard reference work in the field, the new edition of Blood and Bone Marrow Pathology incorporates the latest WHO classification schemes and the latest ancillary diagnostic techniques in immunohistochemistry and molecular biology in order to provide a comprehensive, well balanced and authoritative guide to the interpretation and diagnosis of neoplastic and non-neoplastic diseases of blood and bone marrow. The text is lavishly illustrated with high quality colour images that demonstrate the relevant pathological,features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis The book is lavishly illustrated with high quality color images that demonstrate the relevant pathological features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis. Chapters have been totally rewritten and new chapters have been added, especially on myeloid malignancies. The chapters on hematological malignancies have been written so that the reader can apply the latest WHO Classifications in their routine daily practice (especially the 2008 WHO Classification of Tumors of Hemopoietic and Lymphoid Tissues) All chapters have been revised to include new aspects of molecular biology and flow cytometry diagnostics. Many new schematic diagrams and color illustrations have been added to illustrate blood and bone marrow pathology. Access the full text online and download images via Expert Consult. Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank Already a standard reference work in the field, the new edition of Blood and Bone Marrow Pathology incorporates the latest WHO classification schemes and the latest ancillary diagnostic techniques in immunohistochemistry and molecular biology in order to provide a comprehensive, well balanced and authoritative guide to the interpretation and diagnosis of neoplastic and non-neoplastic diseases of blood and bone marrow. The text is lavishly illustrated with high quality colour images that demonstrate the relevant pathological,features and immunohistochemical and molecular markers. The text features a well-organized approach that incorporates practical tips and clues to help avoid pitfalls and to ensure optimal diagnosis
Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank
This book will assist pathologists, hematologists, and oncologists in interpreting peripheral blood and bone marrow specimens quickly, easily, and accurately. Featuring more than 400 full-color illustrations, the book is a very complete survey of bone marrow diseases, including rare entities, and provides up-to-date information on constitutional and acquired disorders in both adults and children. This edition includes the latest information on hematologic and associated diseases, including many new disease descriptions, recent genetic and immunologic findings, and the current World Health Organization classification of hematolymphoid disorders. A companion Website will offer the fully searchable text and an image bank.
While comprehensive descriptions of the various aspects of Graft-versus-Host Disease (GvHD) have already been published, to date there is no monograph on the clinical and diagnostic pathology of this life-threatening disease. This book fills this gap and serves as a reliable guide to the histomorphologic diagnosis of GvHD. It contains a concise description of: the clinical pathology of GvHD; the applicability and limits of immunohistologic methods in the diagnosis of this disease; an instructive guide to the histological diagnosis; and differential diagnostic problems and potential diagnostic pitfalls.
This book provides a highly illustrated and comprehensive account of the diseases of the human bone marrow. It will help experienced clinicians and those in training to answer the practical diagnostic questions that arise during the routine analysis of bone marrow core biopsy specimens. Throughout the text, histologic interpretation is integrated with clinical and laboratory findings. Emphasis is placed on the evaluation of peripheral blood, aspirate smear, clot section and core biopsy, as well as ancillary techniques including flow cytometry and immunohistochemistry in the diagnosis of hematologic disorders of the marrow. The text is illustrated with numerous color figures, charts and tables, and descriptions of real case situations using the most up-to-date classification systems. Illustrated Pathology of Bone Marrow should be read by all pathologists, hematologists and laboratory technicians involved in the analysis of bone marrow specimens.
The approach described in this book is different from that in most student texts, and has been very successful in practice, starting almost from scratch, but omitting many of the ‘basics’ such as the details of hematopoiesis, laboratory technology, and so on, which are hardly relevant to the practising clinician and student in the wards, and are primarily of interest to the hematologist and sometimes to the clinical specialist. Considerable emphasis is given to the clinical history and examination, and the interpretation of the clinical patterns thus exposed. Hopefully it will overcome many of the traditional problems experienced in practical diagnostic haematology.
No other book covers the pathology of the bone marrow in children as extensively as Pediatric Bone Marrow. It provides a wide background for the understanding of bone marrow disease in children and its difference from that of the adult population. The text illustrates the morphology of the peripheral blood, bone marrow aspirate and bone marrow biopsy. It is useful for the diagnosis of pediatric disorders in the bone marrow, making it an ideal guide for pediatric pathologists, hematologists, oncologists and medical technologists or any physician involved in the diagnosis of pediatric bone marrow disorders.