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This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.
This book reflects the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment of musculoskeletal tumor and tumorlike lesions. It presents a wide range of lesions from a multidisciplinary perspective, highlighting pertinent clinical, radiological, and histological correlations. Treatment is briefly reported for each entity. In addition, the more recent biomolecular findings of use for diagnosis, prognosis, and treatment are carefully analyzed. The Rizzoli case archive spans more than a century, the first treated case dating back to 28 September 1900, and contains the original material – clinical charts, imaging, paraffin blocks, and histological slides – of more than 40,000 cases, including about 29,000 bone lesions and 11,000 soft tissue lesions. This book reports the most relevant entities and reflects the improvements in knowledge of musculoskeletal tumors as presented during the yearly international course held at the Rizzoli Institute.​
Drawing on the Rizzoli Orthopedic Institute's archive of more than 40,000 cases, this superb new resource includes invaluable biomolecular analyses. It covers a vast array of lesions, highlighting clinical, radiological, and histological correlations.
An authoritative reference for everyday clinical practice Practical. In-depth. Invaluable. A guide to the diagnosis of tumors and tumorlike lesions of bone and soft tissue using MRI. This unique encyclopedic guide takes the same approach you apply in clinical practice. It features fully illustrated differential diagnosis tables organized according to MRI findings and the locations of tumors. An in-depth reference section provides information on each lesion. In addition, almost 3000 high quality images make this practical text an invaluable tool in the diagnosis of common and rare tumors and other disorders of the musculoskeletal system. Features: 20 differential diagnosis tables based on anatomic locations of lesions rather than disease Fully illustrated reference chapters containing concise, detailed information for each lesion - from relative frequency and age ranges to MRI findings, treatment, and prognosis Over 2900 state-of-the-art illustrations covering the wide range of imaging features for various lesions An exceptional level of detail, helping you to differentiate between diseases and conditions that have similar appearances Extensive cross-referencing to further up-to-the minute resources This is the definitive guide to MRI of musculoskeletal tumors. Whether you need a practical guide for day-to-day use or a comprehensive preparation tool for board examinations - keep this text close to the workstation.
Practical. In-depth. Invaluable. A guide to the diagnosis of tumors and tumorlike lesions of bone and soft tissue using MRI. This unique encyclopedic guide takes the same approach you apply in clinical practice. It features fully illustrated differential diagnosis tables organized according to MRI findings and the locations of tumors. An in-depth reference section provides information on each lesion. In addition, almost 3000 high quality images make this practical text an invaluable tool in the diagnosis of common and rare tumors and other disorders of the musculoskeletal system. Features: 20 differential diagnosis tables based on anatomic locations of lesions rather than disease Fully illustrated reference chapters containing concise, detailed information for each lesion - from relative frequency and age ranges to MRI findings, treatment, and prognosis Over 2900 state-of-the-art illustrations covering the wide range of imaging features for various lesions An exceptional level of detail, helping you to differentiate between diseases and conditions that have similar appearances Extensive cross-referencing to further up-to-the minute resources This is the definitive guide to MRI of musculoskeletal tumors. Whether you need a practical guide for day-to-day use or a comprehensive preparation tool for board examinations - keep this text close to the workstation.
Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.
Visual Guide to Musculoskeletal Tumors: A Clinical-Radiologic-Histologic Approach, by Felasfa Wodajo, MD; Frank Gannon, MD and Mark Murphey, MD, uses a pattern-recognition approach to help you diagnose challenging musculoskeletal tumors with confidence. With an easy-to-use format, it is the only resource that correlates histology studies and imaging studies. By comparing images these superb-quality, large-scale images, you can master pattern recognition for the 30 most important musculoskeletal tumors and make informed, effective, and rapid decisions on diagnosis and treatment. Master pattern recognition and diagnosis of musculoskeletal tumors with easy-to-use templated chapters and 900 illustrations summarizing essential clinical, histologic, and radiologic findings. Make rapid, confident decisions on diagnosis and treatment by comparing your clinical findings to the book’s extensive collection of detailed, large-scale illustrations.
During the last decade the therapeutic approach to musculoskeletal tumors has changed dramatically, from ablative surgery with ampu tation ofthe limb to reconstructive surgery with transplantation of bone and vessels combined with radio-and chemotherapy. This has changed the demands on radiologists and pathologists to a considerable degree. At the same time there has been a manifold increase in the diagnostic possibilities offered by modern radiology, with several new modalities affording a potential for morphologic depiction and tissue character ization that was unattainable a decade ago. Today, the definitive diagnostic work-up and treatment of patients with musculoskeletal tumors is most often done in tumor centers, by groups that ideally should be composed of an orthopedic surgeon, radiotherapist, oncologist, radiologist, pathologist and cytologist. It is necessary for all the members of this team to be well versed in the surgi cal and other treatment principles, in the pathologic concepts, and in the radiologic interpretation of musculoskeletal tumors. Moreover, it is important that the modern diagnostic approach to musculoskeletal tumors is well known also at the referring center, be it a private practi tioner's office or a large hospital. This will avoid unnecessary biopsies, and repetition of radiologic and other diagnostic procedures that have already been performed at the referring center.
More than ten years have elapsed since the publication of the first edition of Tumors and Tumorlike Lesions of Bone and Joints in 1981. During this period significant progress has been made in diagnosis, and particularly in staging and treatment of bone tumors. In most centers, limb-sparing surgery has replaced the more radical ablative surgery, with or without preoperative chemotherapy. This became possible due to the introduction and increased application of newer high-quality imaging techniques (CT and MRI) and in particular the use of new cytomorphologic methods of diagnosis, especially immunohisto chemistry. These advances in diagnosis and treatment have been reflected by the publication of new editions of several important text books, since their authors - pathologists, orthopedic surgeons, and radiologists - felt the necessity of updating their works in recent years. However, in these publications different criteria of classification were adopted. The number of cases compiled at the Latin American Registry of Bone Pathology increased from 4913 primary bone tumors and more than 1100 tumorlike lesions at the time of publication of the first edition of this book, to 5274 bone tumors and 1665 tumorlike lesions by the end of December 1985, when I finished my work as head of the Registry and occupied the positions of Professor of Orthopedic Pathology at St. Louis University Medical Center and Distinguished Visiting Professor at Rush-Presbyterian-St. Luke's Medical Center in Chicago.