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Of the three types of bladder cancer, Non-Muscle Invasive Bladder Cancer (NMIBC) is the most common form and is diagnosed in over 70% of cases. This issue of the Urologic Clinics focuses on NMIBC and includes articles on periopertive chemotherapy, office fulguration, TURBT, surveillance strategies, and radiation therapy in type-1 tumors.
Of the three types of bladder cancer, Non-Muscle Invasive Bladder Cancer (NMIBC) is the most common form and is diagnosed in over 70% of cases. This issue of the Urologic Clinics focuses on NMIBC and includes articles on periopertive chemotherapy, office fulguration, TURBT, surveillance strategies, and radiation therapy in type-1 tumors.
Together with Consulting Editor Dr. Samir Taneja, Dr. Badrinath Konety has put together a comprehensive issue that addresses Salvage therapies for Non-Muscle Invasive Bladder Cancer. Expert authors have contributed clinical review articles on the following topics: BCG salvage therapy: Definition and context; Who will respond to BCG? Predictors and nomograms; Identification of candidates for salvage therapy: Definition of BCG “Failure ; Predictors of response to Intravesical therapy; Precision medicine for NMIBC; Salvage therapy using BCG derivatives or single agent chemotherapy; Intravesical heated Mitomycin: Biology and clinical utility; Mitomycin derivatives in the salvage setting; Combination intravesical therapy; Intravesical gene therapy; Immunoncology as salvage therapy; Role of IDO inhibitors in salvage therapy; and Novel agents for intravesical therapy. Readers will come away with the clinical information they need to improve outcomes in patients with bladder cancer.
This book covers the latest advances in non-muscle invasive bladder cancer care. It provides a review of the available evidence base for the efficacy of a range of therapeutic techniques, diagnostic procedures and risk factors. Management of Non-Muscle Invasive Bladder Cancer features detailed guidance in uniformly formatted chapters on how to properly apply a range of available therapeutic treatments relevant for patient care. It is a valuable resource for all trainee and practising medical professionals who treat these patients.
Dr. Holzbeierlein has created an issue devoted to the current knowledge and best practice of Bladder Cancer and Upper Tract Urothelial Cell Carcinoma. Top expert authors have written clinical reviews on the following topics: Current Staging Strategies for Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cell Carcinoma; Neoadjuvant Chemotherapy for MIBC and Upper Tract UCC; Bladder Preservation Therapy for MIBC; Pre-Operative and Intraoperative Optimization of the Cystectomy Patient; Robotic Cystectomy; Robotic Nephroureterectomy; Organ Sparing Cystectomy; Lymphadenectomy for MIBC and Upper Tract UCC; ERAS Pathways; Follow-up Management of Cystectomy Patients; Quality of Life after Cystectomy; Endoscopic Approaches to Upper Tract UCC; Adjuvant Therapy in MIBC and Upper Tract UCC; and Immunotherapy in MIBC and Upper Tract UCC. The urologist will have the clinical information he or she needs to treat these patients so as to optimize outcomes.
The Guest Editors have assembled top key opinion leaders to provide current reviews on the multidisciplinary approach to the management of high-grade bladder cancer. Articles are devoted to fluorescence cystoscopy, confocal laser endomicroscopy, narrow band imaging; Novel therapeutic approaches for recurrent nonmuscle invasive bladder cancer; Trimodality therapy in bladder cancer; the data and the reality of perioperative chemotherapy in muscle invasive bladder cancer; radical transurethral resection alone, robotic or partial cystectomy or extended lymphadenectomy: Neoadjuvant paradigm for drug development in muscle invasive bladder cancer; Novel biomarkers to predict response and prognosis in localized bladder cancer; Immunotherapy in Advanced/Metastatic Urothelial Cancer ; and Adjuvant Chemotherapy in High Grade Upper Tract Urothelial Cancer.
Bladder Cancer: Diagnosis and Clinical Management is a 100% clinically-focused guide to bladder cancer, providing practical, modern and evidence-based guidance to the latest in diagnosis and management of the condition. It differs from other books in its complete clinical focus as opposed to a heavy analysis of pathogenesis or basic science. As a result, practicing urologists and oncologists in the clinical setting will find it an essential resource to consult. In addition to the latest in diagnostic tools and imaging methods, core focus is on the management of each form of cancer at its various stages with up to date genomic data and targeted therapies. Both drug therapies and the range of surgical options are covered, ensuring that this is the perfect tool for clinicians to consult when considering which type of management program is appropriate for each individual patient. A key addition is the final section dedicated to optimizing health care delivery, featuring chapters on highly topical issues such as quality of life, patient advocacy and surgical education. Full color throughout, and packed with excellent images, each chapter contains concise and didactic practical tips and tricks to enrich the reading experience, in addition to management algorithms and the very latest guidelines from the ASCO, AUA, ESMO and EAU concerning clinical management of bladder cancer.
This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Guru P. Sonpavde, is devoted to Bladder Cancer. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: Epidemiology of bladder cancer, The molecular biology of bladder cancer and potential implications for therapy, Current therapy for metastatic urothelial carcinoma, Current perioperative therapy for muscle invasive urothelial carcinoma, Current therapy and emerging intravesical agents to treat non-muscle invasive bladder cancer, Diagnosis and staging of bladder and upper tract urothelial cancer, Surgery for bladder and upper tract urothelial cancer, Bladder conserving therapy for muscle invasive bladder cancer: opportunities to incorporate molecular profiling, Emerging immunotherapy for bladder cancer, Emerging targeted therapy for bladder cancer, Real world outcomes of patients with bladder cancer, Preclinical systems to develop bladder cancer therapeutics, Developing precision medicine for bladder cancer, and Future Directions in Bladder Cancer Treatment and Research.
This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Joaquin Bellmunt, is devoted to Bladder Cancer. Articles in this issue include: Diagnosis and Staging of Bladder Cancer; Epidemiology of Bladder Cancer; Molecular Biology of Bladder Cancer; Pharmacogenomics in Bladder Cancer; Management of Non-muscle Invasive Bladder Cancer; Non-urothelial Bladder Cancer and Rare Variant Histologies; Management of UUT; New Trends in Surgical Management of Bladder Cancer; Bladder Preservation Strategies; Perioperative Therapy of Bladder Cancer (Neoadjuvant and Adjuvant); First Line Treatment and Prognostic Factors of Metastatic Disease: Platinum Eligible Patients; First Line Treatment of Metastatic Disease: Platinum Ineligible Patients; Salvage Therapy in Metastatic Disease; and Future Directions and Targeted Therapies in Bladder Cancer.