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This book focuses on the problem of linear approximability, or decomposability for distribution functions. While questions concerning this topics had been raised long ago, only “ad hoc” procedures had been found out. Here, the author deals with the treatment of general methods for this problem.
This book focuses on the problem of linear approximability, or decomposability for distribution functions. While questions concerning this topics had been raised long ago, only ?ad hoc? procedures had been found out. Here, the author deals with the treatment of general methods for this problem.
This volume reviews the theory and simulation methods of stochastic kinetics by integrating historical and recent perspectives, presents applications, mostly in the context of systems biology and also in combustion theory. In recent years, due to the development in experimental techniques, such as optical imaging, single cell analysis, and fluorescence spectroscopy, biochemical kinetic data inside single living cells have increasingly been available. The emergence of systems biology brought renaissance in the application of stochastic kinetic methods.
Finite mixture distributions arise in a variety of applications ranging from the length distribution of fish to the content of DNA in the nuclei of liver cells. The literature surrounding them is large and goes back to the end of the last century when Karl Pearson published his well-known paper on estimating the five parameters in a mixture of two normal distributions. In this text we attempt to review this literature and in addition indicate the practical details of fitting such distributions to sample data. Our hope is that the monograph will be useful to statisticians interested in mixture distributions and to re search workers in other areas applying such distributions to their data. We would like to express our gratitude to Mrs Bertha Lakey for typing the manuscript. Institute oj Psychiatry B. S. Everitt University of London D. l Hand 1980 CHAPTER I General introduction 1. 1 Introduction This monograph is concerned with statistical distributions which can be expressed as superpositions of (usually simpler) component distributions. Such superpositions are termed mixture distributions or compound distributions. For example, the distribution of height in a population of children might be expressed as follows: h(height) = fg(height: age)f(age)d age (1. 1) where g(height: age) is the conditional distribution of height on age, and/(age) is the age distribution of the children in the population.