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In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
This book explores several aspects of the research in the field of general anesthesia, including mechanisms of action of inhaled and intravenous hypnotic agents; the anesthetics-induced neurotoxicity in children and elderly; features and physiopathology of postoperative cognitive side effects; and findings from preclinical research focused on the recognition of potential links between anesthetics and cancer cell biology. Furthermore, chapters in this book cover technical topics such as preoperative monitoring of autonomic nervous activity; EEG based monitoring of general anesthesia; monitoring cerebral oximetry by near infrared spectroscopy; pharmacological issues of anesthesia interest; and optimization of perioperative course through the latest techniques such as the opioid-free anesthesia. Finally, this book offers a comprehensive and up-to-date discussion on the phenomenon of general anesthesia awareness and its potential psychological sequelae. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, General Anesthesia Research is a valuable resource for novice and expert anesthesiologists who want to learn more about the important advances made in this developing field.
A practical guide to perioperative cognitive disorders, the most common complications of anesthesia and surgery in older people.
This book offers an essential guide to managing the most heatedly debated topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia, such as antibiotic therapy in multidrug resistance infection, acute hepatic failure, weaning, ECMO, difficult airway in pediatric patients, goal directed fluid therapy, preoperative anesthesia evaluation and delirium. Written by leading experts and including updated references, it provides a comprehensive, easy-to-follow guide to anesthesia and intensive care. The book clearly explains complex topics, offering practicing clinicians valuable insights into the latest recommendations and evidence in the field while, at the same time, making it a vital resource for students new to the fields of anesthesia and intensive care.
An insightful record charting the history of American anaesthesia.
50 Studies Every Anesthesiologist Should Know presents key studies that have shaped the practice of anesthesiology. Selected using a rigorous methodology, the studies cover topics ranging from pain medicine, critical care, cardiothoracic anesthesiology to general anesthesiology. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case concludes the review. This book is a must-read for health care professionals in anesthesiology and pain medicine, and anyone who wants to learn more about the data behind clinical practice in anesthesiology, pain medicine, critical care and its broad subspecialties.
Addressing both routine and complex situations with practical decision-making tools, Evidence-Based Practice of Anesthesiology, 4th Edition, helps anesthesiologists make sound decisions in everyday practice. World-renowned authority, Dr. Lee A. Fleisher, takes an evidence-based approach to a variety of high-impact topics related to effective perioperative patient management: preoperative assessment; monitoring and administration of anesthesia during surgery; postoperative intensive care management; and postoperative pain management. The 4th Edition has been updated from cover to cover, helping you make informed clinical decisions based on reliable, up-to-date guidance in every aspect of patient care. - Explores important issues in perioperative management, discussing the available options, examining the relevant research, and presenting practical recommendations. - Features concise, to-the-point chapters with numerous quick-reference tables for fast and effective decision making. - Includes decision trees throughout to provide visual guidance and a logical flow of key decision points. - Contains nine new chapters on how to identify patients at risk for postoperative neurocognitive disorder; the best strategy for perioperative ACE and ARB agents; emergency laparotomy; optimal postoperative analgesia and the opiate naïve patient; the best method for perioperative handoffs; myocardial injury after non-cardiac surgery (MINS); and more. - Helps you master the current best practices you need to know for successful day-to-day practice and oral board review. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This widely praised, first-of-its-kind book has been thoroughly updated, expanded, and enriched with extensive new case material, illustrations, and link-outs to multimedia, practice guidelines, and more. Written and edited by outstanding world experts, this was the first and remains the leading single-source volume on intraoperative neurophysiological monitoring (IOM). It is aimed at graduate students and trainees, as well as members of the operative team, including anesthesiologists, technologists, neurophysiologists, surgeons, and nurses. Now commonplace in procedures that place the nervous system at risk, such as orthopedics, neurosurgery, otologic surgery, vascular surgery, and others, effective IOM requires an unusually high degree of coordination among members of the operative team. The purpose of the book is to help students, trainees, and team members acquire a better understanding of one another’s roles and thereby to improve the quality of care and patient safety. From the reviews of the First Edition: “A welcome addition to reference works devoted to the expanding field of nervous system monitoring in the intraoperative period... will serve as a useful guide for many different health care professionals and particularly for anesthesiologists involved with this monitoring modality...An excellent reference...[and] a helpful guide both to the novice and to the developing expert in this field.” ‐‐Canadian Journal of Anesthesia “Impressive... [The book] is well written, indexed, and illustrated...The chapters are all extensively referenced. It is also very good value at the price....I would recommend this book to all residents and especially to all neuroanesthesiologists. It will make a worthwhile addition to their library.” ‐‐Journal of Neurosurgical Anesthesiology
Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals - Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates - Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies