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The second edition of Dental Caries: the Disease and its Clinical Management builds on the success of the prestigious first edition to present an unrivaled resource on cariology. The clinical thrust of the first edition is widened and strengthened to include coverage of the disease in all its variety, from eruption of the first primary tooth to the prevalent forms of the disease in older patients. The centrality of caries control and management to the dental health of all populations is further emphasized, as the book goes beyond the successful treatment of carious lesions to demonstrate the long-term consequences of the non-operative and therapeutic techniques employed.
Abstract: A textbook is intended to serve as a study guide for medical students for becoming well-informed regarding medical statistics for subsequent use in medical research. The theme of the text is to describe the statistical methodology frequently found in published medical research, particularly in the area of chronic diseases. Included are: basic concepts; text of significance; various statistical tests and tables; the use and comparison of survival curves; normally distributed data and their analysis; linear regression models for medical data; other regression models; the quality of data; clinical trial designs; and considerations of sample size. Specific applications to epidemiological studies also are described. Numerous tables, illustrations, and examples are given throughout the text.
Best practices for conducting effective and safe clinical trials Clinical trials are arguably the most important steps in proving drug effectiveness and safety for public use. They require intensive planning and organization and involve a wide range of disciplines: data management, biostatistics, pharmacology, toxicology, modeling and simulation, regulatory monitoring, ethics, and particular issues for given disease areas. Clinical Trials Handbook provides a comprehensive and thorough reference on the basics and practices of clinical trials. With contributions from a range of international authors, the book takes the reader through each trial phase, technique, and issue. Chapters cover every key aspect of preparing and conducting clinical trials, including: Interdisciplinary topics that have to be coordinated for a successful clinical trialData management (and adverse event reporting systems) Biostatistics, pharmacology, and toxicology Modeling and simulation Regulatory monitoring and ethics Particular issues for given disease areas-cardiology, oncology, cognitive, dementia, dermatology, neuroscience, and more With unique information on such current issues as adverse event reporting (AER) systems, adaptive trial designs, and crossover trial designs, Clinical Trials Handbook will be a ready reference for pharmaceutical scientists, statisticians, researchers, and the many other professionals involved in drug development.
On modern dental materials and their applications.
This comprehensive text presents a detailed, heavily illustrated, step-by-step approach to restorative and preventive dentistry. It draws from both theory and practice, and is supported by extensive clinical and laboratory research. Based upon the principle that dental caries is a disease, not a lesion, the book provides both a thorough understanding of caries and an authoritative approach to its treatment and prevention. Now offering a companion Evolve website, this new edition has been updated to address the latest developments in an ever-changing field. Comprehensive coverage of operative dentistry includes fundamentals, diagnosis, instrumentation, preparation, restoration, and prevention, all within a single volume. Up-to-date information covers insurance, safety, and infection control, based on the latest reports and guidelines from organizations such as OSHA and ADA. A clear, consistent presentation describes each restorative process in a linear pattern: initial clinical procedures, tooth preparation, and then restorative technique. Procedural alternatives include multiple approaches to problems wherever applicable, teaching how to adapt a procedure or technique to answer individual patient needs. Pros and cons of restoration options include advantages, disadvantages, indications, and contraindications for restorations. A course-based presentation of topics follows that of many operative dentistry courses, making students' absorption of content stronger and more efficient. 2,550 illustrations include 700 high-quality half-tones and line drawings - more illustrations than any other operative dentistry text. Full-color clinical photos illustrate important concepts - such as coloration and shading on both natural teeth and prostheses. Computer assisted design and computer assisted machining (CAD/CAM) is incorporated into the practice of operative dentistry and related to techniques. Esthetic dentistry instruction is included for this increasingly popular area. Chapter outlines begin each chapter and highlight important topics. Extensive references direct readers to current resources available for additional research. A revised organization groups chapters into five sections, so that locating specific chapters or topics is easier and more efficient: 1. Fundamentals of Operative Dentistry 2. Instrumentation and Preparation 3. Composite Restorations 4. Amalgam Restorations 5. Metal Restorations Procedural Boxes offer step-by-step guides to important procedures, with each step accompanied by a corresponding image. A companion Evolve website features: Approximately 10 audio/video clips illustrating operative techniques and procedures A full-color image collection from the text Links to related content and additional information available on the Internet