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The value of ultrasound contrast agents (USCA) in everyday clinical practice depends on the pharmacokinetics, the signal processing, and the contrast-specific imaging modalities. Second-generation USCA, are blood pool agents that do not leak into the organ tissue to be examined but remain in the intravascular compartment increasing the Doppler signal amplitude during their dynamic vascular phase. Taking advantage of the stability of their microbubbles, they can withstand the acoustic pressure of insonation much better than first-generation contrast media, which results in an increased half-life of the agent and, consequently, in a prolonged diagnostic window. Concomitant with the improvement of contrast agents, different contrast-specific imaging modalities have been developed which, used in combination with USCA and a low mechanical index, allow continuous real-time grey-scale imaging. These recent technical improvements have opened new possibilities in the use of USCA in a variety of indications. Written by internationally renowned experts, the contributions gathered in this book give an overview of current and possible future new applications of USCA in routine and clinical practice.
This book is a comprehensive guide to the rapidly evolving field of contrast-enhanced ultrasound (CEUS) in the child. The uses and interpretation of CEUS are clearly explained with the aid of numerous illustrations. The coverage encompasses both established indications, such as focal liver lesions, abdominal solid organ injury, and vesicoureteral reflux, and a range of newer applications. Extensive information is also provided on microbubble agents and their use in the pediatric age group, as well as on practical aspects of setting up a CEUS service for children. CEUS is a safe imaging method that is ideal for the young patient and can be used for problem solving in a number of clinical situations. Ultrasound combined with microbubble contrast avoids the ionizing radiation of a CT examination, the use of iodinated contrast, the need for sedation or a general anesthetic, and the complexities of MR imaging. In bringing readers up to date with best practice and the latest innovations in CEUS, this book will be of value for pediatric radiologists, pediatric sonographers/technicians, and pediatricians.
In the last few years, the development of sonographic contrast agents - or "microbubbles" - has stimulated increasingly intensive studies on the rela tionships between ultrasound and contrast media. As a result, "contrast -spe cific" hardware and software systems have been introduced by different ultra sound manufacturers with impressive speed. This has finally led to the birth of a very new imaging modality -"contrast-enhanced sonography" (CEUS). Since 1999, the introduction of second-generation contrast agents has represented a decisive step towards the extensive clinical use of CEUS and has simultaneously made obsolete most, if not all, scientific publications available so far. This book is, to our knowledge, the first to deal entirely with second generation contrast agents and the most updated contrast-specific software for noncardiologic uses. The reasons why the liver has been chosen as the only "target" of the book are easily understandable by radiologists and hepatologists alike. The study of vascularity is the only purpose of CEUS, and the liver has a unique vascular system, with two different inflow systems resulting in a single outflow. Furthermore, the pathologically different focal liver lesions (FLLs) are mostly characterized by different "models" of vascularity: CEUS can mimic contrast enhanced computed tomography and magnetic resonance imaging, basing differential diagnosis on the morphological and temporal characteristics of enhancement, but with the additional unique advantage of the study being done in real-time.
Examines in detail the different clinical applications of microbubble-based contrast agents. Explains the principles underlying the use of contrast-specific imaging techniques and the examination methodology. Contains numerous high-quality illustrations, including many in color. Written by recognized experts.
The comparison between methods, evaluation of portal hypertension and many other questions are still open issues in liver elastography. New elastographic applications are under evaluation and close to being used in clinical practice. Strain imaging has been incorporated into many disciplines and EFSUMB guidelines are under preparation. More research is necessary for improved evidence for clinical applications in daily practice. The Special Issue published papers on recent advances in development and application of Ultrasound Elastography.
This volume in the series reflects the rapid advances that have occurred in the use of ultrasound in the investigation of gastroenterology diseases.
This book provides an up-to-date overview on the clinical value of contrast agents in ultrasound. The volume moves from a background section on technique and methodology to the main sections on the clinical application of contrast ultrasound in the liver and in vascular diseases. A final section discusses results and prospects of contrast ultrasound modality in the other fields.
This book is a comprehensive guide to contrast-enhanced mammography (CEM), a novel advanced mammography technique using dual-energy mammography in combination with intravenous contrast administration in order to increase the diagnostic performance of digital mammography. Readers will find helpful information on the principles of CEM and indications for the technique. Detailed attention is devoted to image interpretation, with presentation of case examples and highlighting of pitfalls and artifacts. Other topics to be addressed include the establishment of a CEM program, the comparative merits of CEM and MRI, and the roles of CEM in screening populations and monitoring of response to neoadjuvant chemotherapy. CEM became commercially available in 2011 and is increasingly being used in clinical practice owing to its superiority over full-field digital mammography. This book will be an ideal source of knowledge and guidance for all who wish to start using the technique or to learn more about it.
This atlas presents a comprehensive and state-of-the-art overview of ultrasonography in the head and neck and will serve as a valuable resource for clinicians, surgeons, and otolaryngologists in private practice. The volume addresses all fields of office-based ultrasonography and gives an overview on the physical principles of ultrasound and sonographic techniques, along with detailed demonstrations of typical sonographic characteristics of particular diseases in the head and neck. Written by experts in the field it provides tips and tricks for ultrasound imaging. Subsequent chapters focus on office-based ultrasonography of the face and paranasal sinuses, salivary glands, floor of mouth and tonsil pathology, lymph node pathology, neck masses, thyroid and parathyroid glands, esophagus, and larynx. Special chapters address endosonography of the pharynx and larynx, interventional sonography, and intraoperative sonography. Latest technical developments in the field and their application to clinical ultrasonography are also demonstrated. A brief review of the existing latest literature addressing particular topics follow each chapter. All sonographic findings are demonstrated by high quality ultrasound-pictures and supplementary videos. Ultrasonography of the Head and Neck will serve as a useful guide for all physicians dealing with head and neck ultrasonography and its application to clinical medicine.
Assessment in Health Professions Education, second edition, provides a comprehensive guide for educators in the health professions—medicine, dentistry, nursing, pharmacy, and allied health fields. This second edition has been extensively revised and updated by leaders in the field. Part I of the book presents an introduction to assessment fundamentals and their theoretical underpinnings from the perspective of the health professions. Part II covers specific assessment methods, with a focus on validity, best practices, challenges, and practical guidelines for the effective implementation of successful assessment programs. Part III addresses special topics and recent innovative approaches, including narrative assessment, situational judgment tests, programmatic assessment, mastery learning settings, and the key features approach. This accessible text addresses the essential concepts for the health professions educator and provides the background needed to understand, interpret, develop, and effectively implement assessment methods.