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Dementia in the adult U.S. population is a devastating disorder that is often unrecognized or misdiagnosed in its early stages. Despite the current lack of unequivocally effective treatment, recognition of early-stage dementia may offer substantial benefits. These include avoidance of inappropriate treatment related to misdiagnosis and time for the patient and family to address issues of financial, legal, and medical care planning. This Clinical Practice Guideline is intended to help primary care providers recognize and assess Alzheimer's disease and related dementias in the early stages. Differential diagnosis is beyond the scope of the guideline; however, the guidline contains a list of resources for further clinical evaluation once probable dementia has been identified.
In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.
Neuropsychological Tools for Dementia: Differential Diagnosis and Treatment takes a unique approach by combining the neuroscientific background of neuropsychology, neuropsychological tools for diagnosis and disease staging, and neuropsychological treatment into one comprehensive book for researchers and clinicians. Sections present an introduction to neuropsychological assessment in dementias, Alzheimer’s disease, Parkinson’s disease and Lewy body dementia (alpha-synucleinopathies), atypical Parkinson’s diseases (tauopathies), language and behavioral variants of frontotemporal lobe degeneration, and normal pressure hydrocephalus. Each chapter elucidates the point that neuropsychological measures provide the tools to differentiate disease-specific impairments from normal age-related cognitive decline, and from other neurodegenerative diseases. Moreover, the book discusses the possibility of helping patients through neuropsychological intervention. Case studies aid in the reader’s comprehension of the field, and two short guidelines for each disease’s specific assessment and treatment prepare readers for handling real-life patients. Includes epidemiological information regarding dementia Demonstrates the use of neuropsychological tests and screening tools in diagnosing and differentiating patients with dementia Outlines which investigation strategy and neuropsychological tests work best for assessing patients for different neurodegenerative diseases Reviews specific interventions to slow the progress of dementia wherever possible Discusses the neuropathology, diagnosis and treatment of Alzheimer’s disease
The only guide to focus primarily on current molecular methods of diagnosis and early stage evaluation, this reference presents the latest techniques and technologies for dementia identification and evaluation, including neuropathological strategies, neuropsychological tests, biomarkers, CT, MRI, functional MRI, PET, and SPECT. Offering practical care and examination guidelines, each chapter provides findings that are particularly relevant for the assessment of disorders such as Alzheimer's disease, dementia with Lewy bodies, vascular dementia, and fronto-temporal dementia.
Differential diagnosis of Alzheimer's disease, dementia and delirium, diagnostic tests in differential diagnosis, and identifying underlying conditions that can cause dementia are discussed. Covers drugs to treat cognitive symptoms, managment of agitation and behavioral symptoms, patient management, and support services.
This work focuses on the different patterns of cognitive decline that characterize dementias of various etiologies. The effects of various dementing disorders on different domains of neuropsychological functioning are reviewed, such as attention, memory, intelligence, problem-solving, language skills, visual-spatial functioning, sensory-perceptual abilities, and motor skills. Leading researchers in the field of clinical neuropsychology discuss the unique neuropsychological features of specific dementias and how this information in the context of other clinical data about the patient can aid in making a differential diagnosis. Management issues pertaining to each dementing disorder are also discussed in each chapter. Among the dementing conditions covered are Alzheimer's disease, vascular dementias, dementia associated with alcoholism, tumors, AIDS, and toxicometabolic disorders. Chapters are also devoted to cognitive functioning in normal aging and depression. Up-to-date information concerning neuroimaging, psychopharmacological approaches to treatment, and legal issues in dementia is included in this comprehensive volume.
This important ground-breaking book offers a new approach for understanding and treating Alzheimer's disease. Although there is no cure for this illness, treatment is available for the behavioral and psychosocial problems associated with the course of the disease. Written primarily for physicians, psychiatrists and other mental health professionals who treat people with Alzheimer's disease, this book is also important reading for anyone who has a family member with the infirmity to learn what can be done to alleviate patient suffering and help reduce family burden and stress