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Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. - See more at: http://store.ashp.org/Store/ProductListing/ProductDetails.aspx?productId=153117615#sthash.58RrToYW.dpu Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. - See more at: http://store.ashp.org/Store/ProductListing/ProductDetails.aspx?productId=153117615#sthash.58RrToYW.dpuf Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. - See more at: http://store.ashp.org/Store/ProductListing/ProductDetails.aspx?productId=153117615#sthash.58RrToYW.dpufConcepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. - See more at: http://store.ashp.org/Store/ProductListing/ProductDetails.aspx?productId=153117615#sthash.58RrToYW.dpuf Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find: Content broken into 15 easy-to-follow lessons, perfect for a semester. Practice quizzes in 11 chapters to chart progress. Four chapters completely devoted to clinical cases. More information on hemodialysis More on pharmacogenetics More on plasma concentration versus time curve (AUC) calculations A phenytoin “cheat sheet” to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods More theory and problems on extended interval aminoglycosides. - See more at: http://store.ashp.org/Store/ProductListing/ProductDetails.aspx?productId=153117615#sthash.58RrToYW.dpuf
Understanding the science of pharmacokinetics is a challenge for many pharmacy students and practitioners. Concepts in Clinical Pharmacokinetics, now in its 7th edition, has helped thousands by simplifying this essential, but complex, subject to reflect current practice. The 7th edition has been revised by Robin Southwood, PharmD, BC-ADM, CDE; Virginia H. Fleming, PharmD, BCPS; and Gary Huckaby, PharmD; all experts in clinical pharmacy education. Together, they have updated and expanded the text to include the latest information and insights on concepts through extensive use of correlates, figures, and review questions. Inside you will find: 15 easy-to-follow lessons, perfect for a semester Practice quizzes to help chart progress Enhanced discussion of hemodialysis A phenytoin "cheat sheet" to help you through the calculations maze New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations Expanded information on modified diet in renal disease formula versus Cockcroft-Gault formula methods Factors to consider when choosing a dosing/body weight for various equations Updated clinical correlates, discussion points, references, and questions/answers Concepts in Clinical Pharmacokinetics is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them in clinical practice.
Table of contents: Lesson 1. introduction to pharmacokinetics and pharmacodynamics Lesson 2. basic pharmacokinetics Lesson 3. half-life, elimination rate, and auc Lesson 4. intravenous bolus administration, multiple drug administration, and steady-state average concentrations Lesson 5. relationships of pharmacokinetic parameters and Intravenous intermittent and continuous infusions Lesson 6. two-compartment models Lesson 7. biopharmaceutics: absorption Lesson 8. drug distribution and protein binding Lesson 9. drug elimination processes Lesson 10. nonlinear processes Lesson 11. pharmacokinetic variation and model-independent relationships Lesson 12. aminoglycosides Lesson 13. vancomycin Lesson 14. theophylline Lesson 15. phenytoin and digoxin.
Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help pharmacy students in clinical settings and busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among students, clinical professors, and practitioners. Part I provides a basic review of pharmacokinetic principles, with extensive explanations, graphic illustrations, and detailed algorithms. Part II explains the clinical applications of these principles to problems commonly encountered in the practice setting with specific drugs. This edition includes the latest information on the clinical use of serum drug concentrations. New case studies and examples demonstrate the application of pharmacokinetics in today's clinical practice.
Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of Clinical Pharmacokinetics provides a practical perspective, with these added features considerations of both stereochemistry and the increasing number of polypeptide and protein drugs being developed; the range and number of problems at the end of each chapter has been expanded; a second color added to make the text more user friendly; important equations highlighted by shading.
Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning, and dose related adverse effects. This new edition is specifically aimed at supporting undergraduate studies in pharmacokinetics, and has a strong emphasis on the application of pharmacokinetics in routine clinical practice. Clinical Pharmacokinetics also includes several case studies and 'questions and answers' to further aid understanding and revision.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated
In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.