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This book draws new attention to domain-specific conceptual modeling by presenting the work of thought leaders who have designed and deployed specific modeling methods. It provides hands-on guidance on how to build models in a particular domain, such as requirements engineering, business process modeling or enterprise architecture. In addition to these results, it also puts forward ideas for future developments. All this is enriched with exercises, case studies, detailed references and further related information. All domain-specific methods described in this volume also have a tool implementation within the OMiLAB Collaborative Environment – a dedicated research and experimentation space for modeling method engineering at the University of Vienna, Austria – making these advances accessible to a wider community of further developers and users. The collection of works presented here will benefit experts and practitioners from academia and industry alike, including members of the conceptual modeling community as well as lecturers and students.
This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. - Updated information regarding the most recent in vitro models to study the permeability of drugs - Short and concise chapters covering all the biological barriers with interest in drug permeability - A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models - Simple and clear scientific content, adaptable for young scientists and experimented researchers
Appropriate for undergraduate and graduate students, this text features independent sections that illustrate the most important principles of mathematical modeling, a variety of applications, and classic models. Students with a solid background in calculus and some knowledge of probability and matrix theory will find the material entirely accessible. The range of subjects includes topics from the physical, biological, and social sciences, as well as those of operations research. Discussions cover related mathematical tools and the historical eras from which the applications are drawn. Each section is preceded by an abstract and statement of prerequisites, and answers or hints are provided for selected exercises. 1984 edition.
This brilliant textbook explains in detail the principles of conceptual modeling independently from particular methods and languages and shows how to apply them in real-world projects. The author covers all aspects of the engineering process from structural modeling over behavioral modeling to meta-modeling, and completes the presentation with an extensive case study based on the osCommerce system. Written for computer science students in classes on information systems modeling as well as for professionals feeling the need to formalize their experiences or to update their knowledge, Olivé delivers here a comprehensive treatment of all aspects of the modeling process. His book is complemented by lots of exercises and additional online teaching material.
Understanding and Evaluating Research: A Critical Guide shows students how to be critical consumers of research and to appreciate the power of methodology as it shapes the research question, the use of theory in the study, the methods used, and how the outcomes are reported. The book starts with what it means to be a critical and uncritical reader of research, followed by a detailed chapter on methodology, and then proceeds to a discussion of each component of a research article as it is informed by the methodology. The book encourages readers to select an article from their discipline, learning along the way how to assess each component of the article and come to a judgment of its rigor or quality as a scholarly report.
Discover the essential thinking tools you’ve been missing with The Great Mental Models series by Shane Parrish, New York Times bestselling author and the mind behind the acclaimed Farnam Street blog and “The Knowledge Project” podcast. This first book in the series is your guide to learning the crucial thinking tools nobody ever taught you. Time and time again, great thinkers such as Charlie Munger and Warren Buffett have credited their success to mental models–representations of how something works that can scale onto other fields. Mastering a small number of mental models enables you to rapidly grasp new information, identify patterns others miss, and avoid the common mistakes that hold people back. The Great Mental Models: Volume 1, General Thinking Concepts shows you how making a few tiny changes in the way you think can deliver big results. Drawing on examples from history, business, art, and science, this book details nine of the most versatile, all-purpose mental models you can use right away to improve your decision making and productivity. This book will teach you how to: Avoid blind spots when looking at problems. Find non-obvious solutions. Anticipate and achieve desired outcomes. Play to your strengths, avoid your weaknesses, … and more. The Great Mental Models series demystifies once elusive concepts and illuminates rich knowledge that traditional education overlooks. This series is the most comprehensive and accessible guide on using mental models to better understand our world, solve problems, and gain an advantage.
Research is rooted in philosophical beliefs about values, concepts, and the nature of knowledge. In order to appreciate these philosophical beliefs, several key concepts and terms require consideration and understanding. Complicating the novice researcher’s understanding of these ideas is the unfortunate reality that existing definitions can be confusing. This situation can leave students feeling overwhelmed and confused. The purpose of this book is to provide an overview of major inquiry or research paradigms in a simplified way. The terms discussed in this book include, but are not limited to: Paradigm Axiology Ontology Epistemology Methodology Paradigm shift Positivism Modernism Post-modernism Post-positivism Critical Theory Constructivism Keep in mind that the terms covered in this book are often debated, understood, and communicated in multiple “correct” ways. Also, due to the evolving nature of knowledge and diverse perspectives within the literature, this book serves as an introduction to research terminology that will help you understand, follow, and even participate in this debate. This book will be particularly useful to nursing students who are learning about nursing inquiry. Nursing is a field in which inquiry skills are integral to the development of best evidence and furthering of the profession as a whole.
Models in Microeconomic Theory covers basic models in current microeconomic theory. Part I (Chapters 1-7) presents models of an economic agent, discussing abstract models of preferences, choice, and decision making under uncertainty, before turning to models of the consumer, the producer, and monopoly. Part II (Chapters 8-14) introduces the concept of equilibrium, beginning, unconventionally, with the models of the jungle and an economy with indivisible goods, and continuing with models of an exchange economy, equilibrium with rational expectations, and an economy with asymmetric information. Part III (Chapters 15-16) provides an introduction to game theory, covering strategic and extensive games and the concepts of Nash equilibrium and subgame perfect equilibrium. Part IV (Chapters 17-20) gives a taste of the topics of mechanism design, matching, the axiomatic analysis of economic systems, and social choice. The book focuses on the concepts of model and equilibrium. It states models and results precisely, and provides proofs for all results. It uses only elementary mathematics (with almost no calculus), although many of the proofs involve sustained logical arguments. It includes about 150 exercises. With its formal but accessible style, this textbook is designed for undergraduate students of microeconomics at intermediate and advanced levels.
With the rapid growth of web search in recent years the problem of modeling its users has started to attract more and more attention of the information retrieval community. This has several motivations. By building a model of user behavior we are essentially developing a better understanding of a user, which ultimately helps us to deliver a better search experience. A model of user behavior can also be used as a predictive device for non-observed items such as document relevance, which makes it useful for improving search result ranking. Finally, in many situations experimenting with real users is just infeasible and hence user simulations based on accurate models play an essential role in understanding the implications of algorithmic changes to search engine results or presentation changes to the search engine result page. In this survey we summarize advances in modeling user click behavior on a web search engine result page. We present simple click models as well as more complex models aimed at capturing non-trivial user behavior patterns on modern search engine result pages. We discuss how these models compare to each other, what challenges they have, and what ways there are to address these challenges. We also study the problem of evaluating click models and discuss the main applications of click models.
An A to Z of all the essential concepts and models applied in business and management, from Balanced scorecard and the Boston matrix to Experience curve, Kaizen, McKinsey 's 7S model, Market analysis, Porter 's generic strategies, Relative cost position, Sustainable development to Yield management and Zero-based planning.A superb and comprehensive source of reference for professionals in all sectors of business and MBA students. Bengt Karl'f and Fredrik L'vingsson are successful consultants who have been determined to fill a need for an up to date and approachable A to Z of management concepts, ratios and models. Bengt Karlof is the author of several books published by Wiley.