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Jet fuel with its performance enhancers is highly toxic and when inhaled may pose a significant health risk. Thus, for a scientific assessment of possible health effects from fuel exposure, it is crucial to know where and at what concentrations fuel aerosols and their vapors deposit in the human respiratory system in light of realistic inlet conditions. In contrast to human testing, and/or experimental deposition studies, computational fluid- particle dynamics (CFPD) simulations offer a non-invasive, less expensive, and effective means of obtaining fuel vapor and droplet transport and deposition data for representative airways. Focusing on JP-8 fuel deposition in a representative human upper airway model, experimentally validated CFPD results are provided for the airflow fields, JP-8 fuel droplets, and-JP-8 fuel vapor under realistic ambient conditions. The 3-year-project conclusions, documented in 14 journal articles and 10 conference papers, are divided into three sections, i.e., fundamentals/discoveries, JP-B fuel impact, and technology transfer.
Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
Authored by two longtime researchers in tobacco science, The Chemical Components of Tobacco and Tobacco Smoke, Second Edition chronicles the progress made from late 2008 through 2011 by scientists in the field of tobacco science. The book examines the isolation and characterization of each component. It explores developments in pertinent analytical
Estimates of the air pollution health impact play a crucial role in environmental protection. These estimates require accurate data on the pollutant exposure and dose to the population as well as the dose–response relationships to calculate the health impact. From an air quality manager’s perspective there is concern about the validity and accuracy of these calculations. There is a need for information and possible ways to adjust the assessment. One important topic for air quality managers is to understand the relative cont- bution of sources to the total exposure. These sources may be coming from both different outdoor sources from sectors such as transport, industry and energy ind- tries, and from a number of indoor sources, such as heating, ventilation and indoor activities as well as out-gassing from building material and furniture. Indoor air quality is now drawing the attention of policy makers. The basic right to, and importance of, healthy indoor air was emphasized by the World Health Organization as early as 2000 and several countries have described target conc- trations for various pollutants. The WHO Air Quality Guidelines 2005 rec- mended the development of specific guidelines for indoor air quality and these are expected to be published soon. Indoor air pollutants have not been as extensively monitored as outdoor air pollutants and the evidence base for contributions to health effects needs to be strengthened.
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the informat
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
"The combination of scientific and institutional integrity represented by this book is unusual. It should be a model for future endeavors to help quantify environmental risk as a basis for good decisionmaking." â€"William D. Ruckelshaus, from the foreword. This volume, prepared under the auspices of the Health Effects Institute, an independent research organization created and funded jointly by the Environmental Protection Agency and the automobile industry, brings together experts on atmospheric exposure and on the biological effects of toxic substances to examine what is knownâ€"and not knownâ€"about the human health risks of automotive emissions.
Finishing this book is giving me a mixture of relief, satisfaction and frus tration. Relief, for the completion of a project that has taken too many of my evenings and weekends and that, in the last several months, has become almost an obsession. Satisfaction, for the optimistic feeling that this book, in spite of its many shortcomings and imbalances, will be of some help to the air pollution scientific community. Frustration, for the impossibility of incorporating newly available material that would require another major review of several key chap ters - an effort that is currently beyond my energies but not beyond my desires. The first canovaccio of this book came out in 1980 when I was invited by Computational Mechanics in the United Kingdom to give my first Air Pollution Modeling course. The course material, in the form of transparencies, expanded, year after year, thus providing a growing working basis. In 1985, the ECC Joint Research Center in Ispra, Italy, asked me to prepare a critical survey of mathe matical models of atmospheric pollution, transport and deposition. This support gave me the opportunity to prepare a sort of "first draft" of the book, which I expanded in the following years.