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This Second Edition is the premier name resource in the field. It provides a handy resource for navigating the web of named reactions and reagents. Reactions and reagents are listed alphabetically, followed by relevant mechanisms, experimental data (including yields where available), and references to the primary literature. The text also includes three indices based on reagents and reactions, starting materials, and desired products. Organic chemistry professors, graduate students, and undergraduates, as well as chemists working in industrial, government, and other laboratories, will all find this book to be an invaluable reference.
With its coverage of 701 organic name reactions and reagents, this three-volume set is the largest, most up-to-date major reference work of its kind. It offers students and professional chemists a valuable resource for conducting experiments and performing a broad range of applications, from pharmaceuticals to plastics to pesticides. Each reaction listing is clearly organized into uniform sections that allow readers to quickly gather the information they need to conduct their own experimental procedures Comprehensive Organic Name Reactions and Reagents offers several features that help readers gather information quickly and conduct their experiments successfully: Chemical abbreviations list the abbreviation, the chemical's full name, its structure, and page references Schematic reaction index offers a quick overview of each reaction Reaction summaries provide basic information about each name reaction Reaction type summaries categorize and organize all related name reactions according to the type of transformation (e.g., oxidation, reduction, synthesis of alkenes, etc.)
Rev. ed. of: Organic syntheses based on name reactions and unnamed reactions. 1st ed. 1994.
Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.
This Second edition contains consise information on 134 carefully chosen named organic reactions - the standard set of undergraduate and graduate synthetic organic chemistry courses. Each reaction is detailed with clearly drawn mechanisms, references from the primary literature, and well-written accounts covering the mechanical aspects of the reactions, and the details of side reactions and substrate limitations. For the 2nd edition the complete text has been revised and updated, and four new reactions have been added: Baylis-Hillmann Reaction, Sonogashira Reaction, Pummerer Reaction, and the Swern Oxidation und Cyclopropanation. An essential text for students preparing for exams in organic chemistry.
At last, the long anticipated second edition of the highly successful Encyclopedia of Reagents for Organic Synthesis (EROS) is publishing in print in March 2009. With its wealth of valuable information, excellent editorial leadership and methodical classification, EROS has become the authoritative reference source on reagents and catalysts. This makes EROS vital reading for everybody working in organic synthesis. It has wide appeal, with relevance not only to Organic Chemists, but also to Inorganic, Physical and Analytical Chemists, Materials Scientists, Chemical Engineers, Biochemists, Medicinal and Pharmaceutical Chemists and Pharmacologists. In short, it is an essential product for all academic and industrial chemistry laboratories and libraries. COMPREHENSIVE With its 50,000 reactions and 4,111 reagents, Encyclopedia of Reagents for Organic Synthesis offers readers a substantial wealth of information. Each entry contains, where available: CAS numbers InChI and InChIKeys Alternative names and structures Details on availability and physical properties, including solubility, form in which it’s supplied, purification methods, form obtainable in purification and preparation methods Extensive reviews Examples of transformations for each reagent with reaction schemes Comparison of one agent’s specific properties with those of others capable of equivalent chemistry, together with reaction schemes Stereo-, regio-, and enantio-control properties Required precautions for working with the reagent The various uses and characteristics of each reagent with illustrative examples Related literature METHODICAL Encyclopedia of Reagents for Organic Synthesis has been designed and developed by chemists for chemists. It makes it as easy as possible for users to find the most suitable reagents for performing particular reactions. Reagents are arranged in A to Z format while each reagent entry is presented in a uniform style so that the user is provided with a recognizable format and structure. New in the second edition of Encyclopedia of Reagents for Organic Synthesis: Over 1,000 new reagents Over 620 updated reagents retaining the original text and references whilst adding additional up-to-date information New types of reagents and catalysts In addition to CAS numbers each article now also includes InChI and InChIKeys A standard citation style in the reference list for each reagent An author index
With its coverage of 701 organic name reactions and reagents, this three-volume set is the largest, most up-to-date major reference work of its kind. It offers students and professional chemists a valuable resource for conducting experiments and performing a broad range of applications, from pharmaceuticals to plastics to pesticides. Each reaction listing is clearly organized into uniform sections that allow readers to quickly gather the information they need to conduct their own experimental procedures Comprehensive Organic Name Reactions and Reagents offers several features that help readers gather information quickly and conduct their experiments successfully: Chemical abbreviations list the abbreviation, the chemical's full name, its structure, and page references Schematic reaction index offers a quick overview of each reaction Reaction summaries provide basic information about each name reaction Reaction type summaries categorize and organize all related name reactions according to the type of transformation (e.g., oxidation, reduction, synthesis of alkenes, etc.)
Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs. These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described. - Includes the synthesis of many heterocycles, which is ideal for synthetic organic chemists engaged in the synthesis of heterocyclic systems - Covers the recent advances of asymmetric synthesis of a wide range of heterocycles in satisfactory enantioselectivities (ees) or distereoselectivities (des) - Reviews the synthesis of a wide variety of interesting heterocycles by using a combination of different and versatile name reactions via MCRs
This practical, well-organized reference delves deeply into functional group transformations, to provide all the detailed information that researchers need. Topics are organized into the following sections: oxidation, reduction, asymmetric synthesis, and functional group manipulations Each section includes a description of the functional group transformation, the historical perspective, mechanisms, variations and improvements on the reaction, synthetic utilities and applications for the reaction, experimental details, and references to the primary literature Contributors are well-known and respected for their work on the specific name reactions.