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The material of the present book is an extension of a graduate course given by the author at the University "Al.I. Cuza" Iasi and is intended for stu dents and researchers interested in the applications of optimal control and in mathematical biology. Age is one of the most important parameters in the evolution of a bi ological population. Even if for a very long period age structure has been considered only in demography, nowadays it is fundamental in epidemiology and ecology too. This is the first book devoted to the control of continuous age structured populationdynamics.It focuses on the basic properties ofthe solutions and on the control of age structured population dynamics with or without diffusion. The main goal of this work is to familiarize the reader with the most important problems, approaches and results in the mathematical theory of age-dependent models. Special attention is given to optimal harvesting and to exact controllability problems, which are very important from the econom ical or ecological points of view. We use some new concepts and techniques in modern control theory such as Clarke's generalized gradient, Ekeland's variational principle, and Carleman estimates. The methods and techniques we use can be applied to other control problems.
Interest in the temporal fluctuations of biological populations can be traced to the dawn of civilization. How can mathematics be used to gain an understanding of population dynamics? This monograph introduces the theory of structured population dynamics and its applications, focusing on the asymptotic dynamics of deterministic models. This theory bridges the gap between the characteristics of individual organisms in a population and the dynamics of the total population as a whole. In this monograph, many applications that illustrate both the theory and a wide variety of biological issues are given, along with an interdisciplinary case study that illustrates the connection of models with the data and the experimental documentation of model predictions. The author also discusses the use of discrete and continuous models and presents a general modeling theory for structured population dynamics. Cushing begins with an obvious point: individuals in biological populations differ with regard to their physical and behavioral characteristics and therefore in the way they interact with their environment. Studying this point effectively requires the use of structured models. Specific examples cited throughout support the valuable use of structured models. Included among these are important applications chosen to illustrate both the mathematical theories and biological problems that have received attention in recent literature.
This is a collection of refereed papers presented at the 4th International Conference on Mathematical Population Dynamics. The selection of papers and their organization were made by the following persons: O Arino, D Axelrod, V Capasso, W Fitzgibbon, P Jagers, M Kimmel, D Kirschner, C Mode, B Novak, R Sachs, W Stephan, A Swierniak and H Thieme.It features some of the new trends in cell and human population dynamics. The main link between the two traits is that human populations of concern here are essentially those subject to cell diseases, either the processes of anarchic proliferation or those by which some cell lines are killed by an infectious agent.The volume is divided into 3 main parts. Each part is subdivided into chapters, each chapter concentrating on a specific aspect. Each aspect is illustrated by one or several examples, developed in sections contributed by several authors. A detailed introduction for each part will enable the reader to refer to chapters of interest. An index and a bibliography for each part is also included for easy reference.This book will be useful for those interested in the subject matter.