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Comparative Virology provides an integrated comparison of viruses, based on their chemical and morphological characteristics. These descriptions will not only give the reader a background but also a detailed analysis of the various groups. In some instances the groups are still host related, as in the case of bacteriophages and polyhedral insect viruses. In others, for instance in pox viruses, the group comprises viruses of vertebrates and invertebrates. The hosts of the bacilliform Rhabdovirales range from man and other warm-blooded vertebrates through invertebrate animals to plants. A special chapter is devoted to viruses devoid of protein—a group that is of great interest and that has only recently been recognized. Since there is historical and practical interest in écologie groupings, such as arboviruses and oncogenic viruses, chapters on such groups have also been included. The book opens with a discussion on the classification of viruses. Chapters dealing with DNA viruses and RNA viruses follow, and the ecologically and disease-oriented groups complete the volume. It is hoped that ""Comparative Virology"" will help bring unity to the science of virology through the comparative approach that is not dependent on virus-host interactions. The combined efforts of eminent contributors to discuss and evaluate new information will hopefully benefit all who are interested in virology
Comparative Plant Virology provides a complete overview of our current knowledge of plant viruses, including background information on plant viruses and up-to-date aspects of virus biology and control. It deals mainly with concepts rather than detail. The focus will be on plant viruses but due to the changing environment of how virology is taught, comparisons will be drawn with viruses of other kingdomes, animals, fungi and bacteria. It has been written for students of plant virology, plant pathology, virology and microbiology who have no previous knowledge of plant viruses or of virology in general. - Boxes highlight important information such as virus definition and taxonomy - Includes profiles of 32 plant viruses that feature extensively in the text - Full color throughout
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
It has been known for a long time that the majority of plant viruses contain RNA and in the past decade and a half it has been realized that many have genomes consisting of three molecules of single-stranded RNA with positive polarity. Among these are viruses belonging to four groups recognized by the International Committee for Virus Taxonomy: the Bromovirus and Cucumovirus groups whose genomes are encapsi dated in small icosahedral particles or the Ilarvirus and alfalfa mosaic virus groups with spheroidal or bacilliform particles. In addition to their tripartite genomes, these viruses share a number of other properties and it has been proposed that they should perhaps be grouped in a single virus family for which the name Tricornaviridae has been suggested, the tri indicating the tripartite nature of the genome, the co emphasizing the cooperation of the three genome parts required to initiate infection, and the rna indicating that the genome is composed of RNA. Viruses of this "family" are less uniform in their biological proper ties. A number of them are widespread, causing very destructive plant diseases. Viruses such as those of cucumber mosaic and alfalfa mosaic have very extensive host ranges and are responsible for serious crop losses in many parts of the world. Others such as prunus necrotic ringspot or prune dwarf viruses are more restricted in their host ranges but never theless infect important perennial hosts such as stone fruits and reduce productivity considerably.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having only recently passed through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have so far been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective as well as to develop an invaluable reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere but which also provides a logical progression of developing facts and integrated concepts.
Comparative Diagnosis of Viral Diseases, Volume III: Vertebrate Animal and Related Viruses Part A—DNA Viruses, is devoted to vertebrate animal and related viruses. This book covers in separate chapters the infections caused by each DNA virus family, including slow viruses diseases, as well as the system of Virus Information of the World Health Organization. It provides a comparative description of the principal physicochemical, molecular, structural, genetic, immunological, and biological characteristics of viruses implicated in various diseases, mainly of veterinary importance. With this new concept of comparative diagnosis, the symptoms and the evolution of the diseases are described in detail, as well as the modern methodology for their rapid and specific diagnosis, control, and prevention. This text will interest all virologists and immunologists working in the area of diagnosis and control of animal virus diseases. In particular, it is addressed to the professionals of veterinary sciences working both in the field and in the laboratory and to students of veterinary schools.
Virus Structure describes the physical characteristics of isolated viruses that represent typical structural groups, with particular reference to those features analyzed with the aid of the electron microscope. For descriptive purposes, the book has been divided into sections starting with the small icosahedral viruses and leading to the larger and more sophisticated structures, regardless of whether they are animal, plant, or bacterial viruses. These include double-stranded DNA icosahedral viruses, herpesvirus, viruses with helical symmetry, and viruses with complex or a combination of symmetries. Many common architectural features will be found in those viruses selected for discussion in each of the sections, and for these reasons the introduction places some emphasis on the symmetry elements rather than the shapes of viruses. The mechanism by which viruses enter host cells and the events that follow once the cell has been infected are only mentioned briefly as the virus-host interaction is a relatively complex one.
The study of viruses, or virology as it is now called, had its origin in 1892 when a Russian botanist, Iwanawsky, showed that sap from a tobacco plant with an infectious disease was still highly infectious after passage through a filter capable of retaining bacterial cells. From such humble beginnings the study of these 'filter-passing agents', or viruses, has developed into a separate science which rivals, if it does not excel, in importance the whole of bacteriology. The importance of viruses lies not only in the diseases they cause in every type of living organism, but also because of their intimate relationship with the living cell, in which alone they can reproduce. Their study has influenced the whole of biology by greatly increasing our knowledge of the gene, genetics, and molecular structure; there is also the possible connexion of viruses with human cancer, in view of the occurrence of many viral cancers in other animals. The book attempts to give a comprehensive but necessarily superficial survey of the subject as a whole and should help senior undergraduates and postgraduate students who wish to gain some knowledge of virology. Further information is available from the extensive bibliography.