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Comparative Biology of the Normal Lung, Second Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung. Edited and authored by experts in the field to provide an excellent and timely review of cross-species comparisons that will help you interpret and compare data from animal studies to human findings Incorporates lung anatomy and physiology, cell specific interactions and immunological responses to provide you with a single and unique multidisciplinary source on the comparative biology of the normal lung Includes new and expanded content on neonatal and aged lungs, developmental processes, cell signaling, antioxidants, airway cells, safety pharmacology and much more Section IV on Physical and Immunological Defenses has been significantly updated with 9 new chapters and an increased focus on the pulmonary immunological system
Comparative Biology of the Normal Lung is the first volume in a series entitled "A Comprehensive Treatise on Pulmonary Toxicology." The book is divided into four sections that deal with morphology and morphometry, respiratory physiology, biochemistry, and pulmonary defense. A special index lists and cross indexes all comparative data included in the text, which provides readers with easy access to a broad spectrum of pulmonary data for a number of different species. Over 50 internationally respected authors have contributed to this cutting -edge scientific study designed for all scientists concerned with the pulmonary system, including research scientists in medicine, veterinary medicine, zoology, and toxicology.
Comparative Biology of the Normal Lung is the first volume in a series entitled "A Comprehensive Treatise on Pulmonary Toxicology." The book is divided into four sections that deal with morphology and morphometry, respiratory physiology, biochemistry, and pulmonary defense. A special index lists and cross indexes all comparative data included in the text, which provides readers with easy access to a broad spectrum of pulmonary data for a number of different species. Over 50 internationally respected authors have contributed to this cutting -edge scientific study designed for all scientists concerned with the pulmonary system, including research scientists in medicine, veterinary medicine, zoology, and toxicology.
Twenty-six state-of-the-art studies explore the energy demand structure and function of the gas exchange organ, gas exchange and transport, fluid balance, mechanisms and control of breathing, and diving physiology of virtually the entire animal world fish, amphibians, reptiles, marine mammals, birds
Respiratory Physiology of Newborn Mammals: A Comparative Perspective emphasizes common trends among mammalian species in an effort to extract general rules about both the structure and the mechanisms of neonatal respiration. Jacopo P. Mortola outlines the key aspects of developmental respiratory physiology in the perinatal period. Based on what is learned from interspecies comparisons, Mortola addresses the question of how pulmonary ventilation fulfills the metabolic requirements of the newborn infant. Exceptions to the rules illuminate adaptations to particular tasks or conditions. Each chapter concludes with interspecies comparisons and clinical implications for the medically or zoologically oriented reader. The combination of developmental and comparative perspectives offers an original contribution to the field of developmental physiology. The book is divided into five chapters: "Gestation and Birth," Metabolic and Ventilatory Requirements," "Mechanical Behavior of the Respiratory Pump," "Reflex Control of the Breathing Pattern," and "Changes in Temperature and Respiratory Gases." It will be of value to researchers, clinicians, and students interested in developmental physiology, comparative biology, and zoology, as well as neonatalogists and pediatric pulmonologists who are interested in alternative perspectives on current clinical practice. -- W. Alan Hodson, M.D., University of Washington Medical Center