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Due to a worldwide need for lower cost drug therapy, use of generic and multi-source drug products have been increasing. To meet international patent and trade agreements, the development and sale of these products must conform to national and international laws, and generic products must prove that they are of the same quality and are therapeutica
Accompanying CD-ROM contains the complete text of the printed volume.
Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.
Reflecting the author’s years of industry and teaching experience, Fluid Mechanics and Turbomachinery features many innovative problems and their systematically worked solutions. To understand fundamental concepts and various conservation laws of fluid mechanics is one thing, but applying them to solve practical problems is another challenge. The book covers various topics in fluid mechanics, turbomachinery flowpath design, and internal cooling and sealing flows around rotors and stators of gas turbines. As an ideal source of numerous practice problems with detailed solutions, the book will be helpful to senior-undergraduate and graduate students, teaching faculty, and researchers engaged in many branches of fluid mechanics. It will also help practicing thermal and fluid design engineers maintain and reinforce their problem-solving skills, including primary validation of their physics-based design tools.
There has been a tremendous growth in the Hedge Fund industry in recent years. It is estimated that there are more than 8000 Hedge Funds in the US alone. They have grown in popularity since the bear market of the early 2000s which convinced many people that they cannot just own stocks outright or inside mutual funds. Most investors understand mutual funds. They understand that the manager selects stocks and buys them. They also understand why they made (or lost) money in their mutual fund investments. The same thing cannot be said about Hedge Funds which come in a variety of flavors. Even savvy investors are often hard pressed to explain the sources of return on their Hedge Funds. This book should be read by anyone who has invested in, or is considering an investment in, a Hedge Fund and also by anyone who is considering starting one. The book explains the different types of funds as well as covering the key issues in every type of Hedge Fund. This book covers the entire gamut of the Hedge Fund industry. The authors explain the different styles of Hedge Funds (e.g. market neutral, convertible bond arbitrage, fixed income arbitrage and many more) and include a summary for each style of fund. The book also explains what a "fund of funds is, and covers the recently introduced capital guarantees and describes the capital preservation concerns that are faced by investors.