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Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various “omics” technologies and their application in oncology are described as oncogenomics and oncoproteomics. This detailed volume also explores molecular diagnostics, nanobiotechnology, cell and gene therapies, as well as personalized oncology. With approximately one thousand selected references from recent literature on this topic and numerous tables and figures, Applications of Biotechnology in Oncology serves as an ideal reference for oncologists, scientists involved in research on cancer biology, and physicians in various specialties who deal with cancer.
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
The Biotech Primer takes an in-depth look at the biotech industry, and in particular, the science that drives it. From cell structure to protein structure; gene expression to genetic variation and genetic engineering; the human immune response to the production of antibodies for biotech application; and finally drug discovery, drug development, and biomanufacturing: we discuss the key concepts and technologies that impact current biotechnology developments. This book will support your growth as a biotechnology professional. Although the industry itself is constantly changing, these fundamental concepts upon which it is built will remain important for years to come: and decision-makers who understand these fundamentals will be better able to evaluate and predict new trends. More than anything else, we hope that your understanding of the science behind biotechnology will serve to increase your enthusiasm for this exciting and truly life-changing industry. The future is here and you should be a part of it.
Ground-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.
" ... An absorbing narrative history of breast cancer told through the heroic stories of women who have confronted the disease."--Back cover.
The expansion of the pulp and paper industry is one of the most important causes of land and water conflicts in the South. This book examines the threat to livelihood, soil and biodiversity generated by large-scale pulpwood plantations in the South.
Herodotus’ Histories can be read in many ways. Their literary qualities, never in dispute, can be more fully appreciated in the light of recent developments in the study of pragmatics, narratology, and orality. Their intellectual status has been radically reassessed: no longer regarded as naïve and ‘archaic’, the Histories are now seen as very much a product of the intellectual climate of their own day - not only subject to contemporary literary, religious, moral and social influences, but actively contributing to the great debates of their time. Their reliability as historical and ethnographic accounts, a matter of controversy even in antiquity, is being debated with renewed vigour and increasing sophistication. This Companion offers an up-to-date and in-depth overview of all these current approaches to Herodotus’ remarkable work.
A NEW YORK TIMES NOTABLE BOOK • The dramatic story of the Flint water crisis, by a relentless physician who stood up to power. “Stirring . . . [a] blueprint for all those who believe . . . that ‘the world . . . should be full of people raising their voices.’”—The New York Times “Revealing, with the gripping intrigue of a Grisham thriller.” —O: The Oprah Magazine Here is the inspiring story of how Dr. Mona Hanna-Attisha, alongside a team of researchers, parents, friends, and community leaders, discovered that the children of Flint, Michigan, were being exposed to lead in their tap water—and then battled her own government and a brutal backlash to expose that truth to the world. Paced like a scientific thriller, What the Eyes Don’t See reveals how misguided austerity policies, broken democracy, and callous bureaucratic indifference placed an entire city at risk. And at the center of the story is Dr. Mona herself—an immigrant, doctor, scientist, and mother whose family’s activist roots inspired her pursuit of justice. What the Eyes Don’t See is a riveting account of a shameful disaster that became a tale of hope, the story of a city on the ropes that came together to fight for justice, self-determination, and the right to build a better world for their—and all of our—children. Praise for What the Eyes Don’t See “It is one thing to point out a problem. It is another thing altogether to step up and work to fix it. Mona Hanna-Attisha is a true American hero.”—Erin Brockovich “A clarion call to live a life of purpose.”—The Washington Post “Gripping . . . entertaining . . . Her book has power precisely because she takes the events she recounts so personally. . . . Moral outrage present on every page.”—The New York Times Book Review “Personal and emotional. . . She vividly describes the effects of lead poisoning on her young patients. . . . She is at her best when recounting the detective work she undertook after a tip-off about lead levels from a friend. . . . ‛Flint will not be defined by this crisis,’ vows Ms. Hanna-Attisha.”—The Economist “Flint is a public health disaster. But it was Dr. Mona, this caring, tough pediatrican turned detective, who cracked the case.”—Rachel Maddow