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While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies. The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure–function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention. Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines. Key Features: Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics Features new chapters on the "Evolution of Anticancer Therapies", "Antibody-Based Therapies", and "Cancer Chemoprevention"
The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.
What if your path to a more successful, healthy, and satisfying life is actually not about you? Enough About Me equips you with practical tools to find meaning and compassion in even the smallest of everyday choices. When his father was diagnosed with Alzheimer's disease, Richard Lui made a tough decision. The award-winning news anchor decided to set aside his growing career to care for his family. At first, this new caregiving lifestyle did not come easily for Lui, and what followed was a seven-year exercise in what it really means to be selfless. Enough About Me also takes a behind-the-scenes look at some of the world's most difficult moments from a journalist's point of view. From survivors of terrorist attacks to victims of racial strife, Lui shares the lessons he learned from those who rose above the fray to be helpful, self-sacrificing, and generous in the face of monumental tragedy and loss. Lui shares practical tips, tools, and mnemonics learned along the way to help shift the way we think and live, including: Selfless decision methods and practices for work, home, relationships, and community Studies and research that show the personal benefits of being selfless The lasting impact of sharing your story Practical, bite-sized ways to be more engaging and inclusive in your day-to-day life How to train our decision-making muscles to choose others over ourselves Choice by choice, step by step, the path to a more satisfying and fulfilling journey is right here in the people around us. Praise for Enough About Me: "Richard Lui underscores the importance of sharing stories to bring people together through selfless acts for the greater good." Beth Kallmyer, Vice President of Care and Support, Alzheimer's Association "Richard is living a life of service. This is a jewel of a book, a celebration of the best of the human spirit and of the good that emerges from sacrifice. Richard Lui is a beacon of light in these dark times." José Díaz-Balart, Anchor, NBC Nightly News Saturday; Anchor, Noticias Telemundo
The first medical specialty selection guide written by residents for students! Provides an inside look at the issues surrounding medical specialty selection, blending first-hand knowledge with useful facts and statistics, such as salary information, employment data, and match statistics. Focuses on all the major specialties and features firsthand portrayals of each by current residents. Also includes a guide to personality characteristics that are predominate with practitioners of each specialty. “A terrific mixture of objective information as well as factual data make this book an easy, informative, and interesting read.” --Review from a 4th year Medical Student
The Bad Bug was created from the materials assembled at the FDA website of the same name. This handbook provides basic facts regarding foodborne pathogenic microorganisms and natural toxins. It brings together in one place information from the Food & Drug Administration, the Centers for Disease Control & Prevention, the USDA Food Safety Inspection Service, and the National Institutes of Health.