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The discovery of antibiotics heralded medicine's triumph over previously fatal diseases that once destroyed entire civilizations - thus earning their reputation as miracle drugs. But today, the terrifying reality of antibiotic-resistant bacteria resulting from our widespread misuse of antibiotics forewarns us that the miracle may be coming to an end. The seemingly innocent consumer who demands antibiotics to treat nonbacterial diseases such as the common cold or plays doctor by saving old prescriptions for later use is paving the way for a future of antibiotic failure. "What harm can it do?" is a popular refrain of people worldwide as they pop another antibiotic pill. Dr. Stuart Levy - the leading international expert on hazards of antibiotic misuse - reveals how this cavalier and naive attitude about the power of antibiotics can have deadly consequences. He explains that we are presently witnessing a massive evolutionary change in bacteria. This build-up of new antibiotic-resistant bacteria in individuals and the environment worldwide is an insidious and silent process. Thus, unwittingly consumers encounter resistant bacteria in their meat, poultry, fish, and vegetables. Unregulated dispensing of antibiotics in poorer countries breeds countless more resistant strains. Since bacteria recognize no geographical boundaries, resistant forms can travel the globe. If this trend continues to grow unchecked, we may someday find that all of our antibiotics are obsolete. Today doctors can no longer expect that their first choice of antibiotic for women's urinary tract infections or children's ear infections will work. Similarly, cancer therapy is rendered useless if patients are unable to fight infections that are sometimes resistant to eight to ten different drugs. In developing countries, people are now dying of previously treatable diseases that are no longer responsive to traditional antibiotics. These problems are just a harbinger of what will come if we do not act now. Dr. Levy, recognized by The New Yorker for his superb contributions to this field, is sending out an urgent message that the world cannot afford to ignore any longer. The goal of this unprecedented investigation into the dangers of antibiotic misuse is to protect the world community from resistant infections and ensure the success of antibiotics for generations to come
Poliomyelitis, better known as polio, thoroughly stumped the medical science community. Polio's impact remained highly visible and sometimes lingered, exacting a priceless physical toll on its young victims and their families as well as transforming their social worlds. This social history of infantile paralysis is plugged into the rich and dynamic developments of the United States during the first half of the twentieth century. Children became epidemic refugees because of anachronistic public health policies and practices. They entered the emerging, clinical world of the hospital, rupturing physical and emotional connections with their parents and siblings. As they underwent rehabilitation, they created ward cultures. They returned home to occasionally find hostile environments and always discover changed relationships due to their disabilities. The changing concept of the child, from an economic asset to an emotional commitment, medical advances, and improved sanitation policies led to significant improvements in child health and welfare. This study, relying on published autobiographies, memoirs, and oral histories, captures the impact of this disease on children's personal lives, encompassing public-health policies, hospitalization, philanthropic and organizational responses, physical therapy, family life, and schooling. It captures the anger, frustration, and terror not only among children but parents, neighbors, and medical professionals alike.
What role did drug abuse play in John F. Kennedy's White House, and how was it kept from the public? How did general anesthetics and aging affect the presidency of Ronald Reagan? Why did Winston Churchill become more egocentric, Woodrow Wilson more self- righteous, and Josef Stalin more paranoid as they aged—and how did those qualities alter the course of history? Was Napoleon poisoned with arsenic or did underlying disease account for his decline at the peak of his power? Does syphilis really explain Henry VIII's midlife transformation? Was there more than messianism brewing in the brains of some zealots of the past, among them Adolf Hitler, Joan of Arc, and John Brown? Most important of all, when does one man's illness cause millions to suffer, and when is it merely a footnote to history? To answer such questions requires the clinical intuition of a practicing physician and the scholarly perspective of a trained historian. Bert Park, who qualifies on both counts, offers here fascinating second opinions, basing his retrospective diagnoses on a wide range of sources from medicine and history. Few books so graphically portray the impact on history of physiologically compromised leadership, misdiagnosis, and inappropriate medical treatment. Park not only untangles medical mysteries from the past but also offers timely suggestions for dealing with such problems in the future. As a welcome sequel to his first work, The Impact of Illness on World Leaders, this book offers scholars, physicians, and general readers an entertaining, albeit sobering, analysis.
"Jie Jack Li is a medicinal chemist and is intimately involved with drug discovery. Through extensive research and interviews with the inventors of drugs, including those of Viagra and Lipitor, he has assembled an astounding number of facts and anecdotes, as well as much useful information about important drugs we know and use in our lives today. Figures, diagrams, and illustrations highlight the text throughout."--BOOK JACKET.
Anagram Solver is the essential guide to cracking all types of quiz and crossword featuring anagrams. Containing over 200,000 words and phrases, Anagram Solver includes plural noun forms, palindromes, idioms, first names and all parts of speech. Anagrams are grouped by the number of letters they contain with the letters set out in alphabetical order so that once the letters of an anagram are arranged alphabetically, finding the solution is as easy as locating the word in a dictionary.
This book marks a critical contribution in assessing and extending the evidence base on the causes and consequences of women’s homelessness. Drawing together work from Europe’s leading homelessness scholars, it presents a multidisciplinary and comparative analysis of this acute social problem, including its relationship with domestic violence, lone parenthood, motherhood, health and well-being and women’s experience of sustained and recurrent homelessness. Working from diverse perspectives, the authors look at the responses to women’s homelessness in differing cultures and regions, and within various forms of welfare states. They focus in particular on relating the gender dimensions of welfare and social policy to women’s experiences when they become homeless. This innovative and timely edited volume will appeal to students and scholars of sociology, social policy, anthropology, and gender and women’s studies, along with international policy-makers.
In The Impact of Illness on World Leaders, Bert E. Park explores the relationship between leadership and neurologic illness. Basing his study on a rigorous examination of primary and secondary source material from medicine, history, and political science, Park diagnoses illnesses which affected the thinking and actions of Anthony Eden and Adolf Hitler, among others. He discusses the historical situations in which these political leaders functioned and the effects their illnesses might have had on the decisions they made. Park argues that the impact of aging and disease on leadership abilities is an important, potentially devastating problem which has been ignored by the people in a position to deal with it. Physicians who attend men in power, supported by government officials and politicians, often disguise their patients' infirmities and keep them in office long after they are able to function effectively. In those few instances when the problem has been addressed, it has often been done by journalists or other persons not qualified to make a medical judgment about a leader's health, and they have relayed erroneous information (e.g., the myth of Hitler's syphilis). Part of the goal of The Impact of Illness on World Leaders is to correct such popular misconceptions. Park concludes his study of leadership and illness with suggestions for monitoring the health of leaders and deposing them if their health compromises their ability to lead.