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A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
The award-winning New York Times bestseller about the American women who secretly served as codebreakers during World War II--a "prodigiously researched and engrossing" (New York Times) book that "shines a light on a hidden chapter of American history" (Denver Post). Recruited by the U.S. Army and Navy from small towns and elite colleges, more than ten thousand women served as codebreakers during World War II. While their brothers and boyfriends took up arms, these women moved to Washington and learned the meticulous work of code-breaking. Their efforts shortened the war, saved countless lives, and gave them access to careers previously denied to them. A strict vow of secrecy nearly erased their efforts from history; now, through dazzling research and interviews with surviving code girls, bestselling author Liza Mundy brings to life this riveting and vital story of American courage, service, and scientific accomplishment.
Walter Isaacson’s #1 New York Times bestselling history of our third scientific revolution: CRISPR, gene editing, and the quest to understand the code of life itself, is now adapted for young readers! When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a closely related molecule that enables the genetic instructions coded in DNA to express themselves. Doudna became an expert in determining the shapes and structures of these RNA molecules —an expertise that led her to develop a revolutionary new technique that could edit human genes. Today gene-editing technologies such as CRISPR are already being used to eliminate simple genetic defects that cause disorders such as Tay-Sachs and sickle cell anemia. For now, however, Jennifer and her team are being deployed against our most immediate threat—the coronavirus—and you have just been given a front row seat to that war.
Jack the Ripper and legacy codebases have more in common than you'd think. Inspired by forensic psychology methods, you'll learn strategies to predict the future of your codebase, assess refactoring direction, and understand how your team influences the design. With its unique blend of forensic psychology and code analysis, this book arms you with the strategies you need, no matter what programming language you use. Software is a living entity that's constantly changing. To understand software systems, we need to know where they came from and how they evolved. By mining commit data and analyzing the history of your code, you can start fixes ahead of time to eliminate broken designs, maintenance issues, and team productivity bottlenecks. In this book, you'll learn forensic psychology techniques to successfully maintain your software. You'll create a geographic profile from your commit data to find hotspots, and apply temporal coupling concepts to uncover hidden relationships between unrelated areas in your code. You'll also measure the effectiveness of your code improvements. You'll learn how to apply these techniques on projects both large and small. For small projects, you'll get new insights into your design and how well the code fits your ideas. For large projects, you'll identify the good and the fragile parts. Large-scale development is also a social activity, and the team's dynamics influence code quality. That's why this book shows you how to uncover social biases when analyzing the evolution of your system. You'll use commit messages as eyewitness accounts to what is really happening in your code. Finally, you'll put it all together by tracking organizational problems in the code and finding out how to fix them. Come join the hunt for better code! What You Need: You need Java 6 and Python 2.7 to run the accompanying analysis tools. You also need Git to follow along with the examples.
"As gripping as a good thriller." --The Washington Post Unpack the science of secrecy and discover the methods behind cryptography--the encoding and decoding of information--in this clear and easy-to-understand young adult adaptation of the national bestseller that's perfect for this age of WikiLeaks, the Sony hack, and other events that reveal the extent to which our technology is never quite as secure as we want to believe. Coders and codebreakers alike will be fascinated by history's most mesmerizing stories of intrigue and cunning--from Julius Caesar and his Caeser cipher to the Allies' use of the Enigma machine to decode German messages during World War II. Accessible, compelling, and timely, The Code Book is sure to make readers see the past--and the future--in a whole new way. "Singh's power of explaining complex ideas is as dazzling as ever." --The Guardian
A sweeping, in-depth history of NSA, whose famous “cult of silence” has left the agency shrouded in mystery for decades The National Security Agency was born out of the legendary codebreaking programs of World War II that cracked the famed Enigma machine and other German and Japanese codes, thereby turning the tide of Allied victory. In the postwar years, as the United States developed a new enemy in the Soviet Union, our intelligence community found itself targeting not soldiers on the battlefield, but suspected spies, foreign leaders, and even American citizens. Throughout the second half of the twentieth century, NSA played a vital, often fraught and controversial role in the major events of the Cold War, from the Korean War to the Cuban Missile Crisis to Vietnam and beyond. In Code Warriors, Stephen Budiansky—a longtime expert in cryptology—tells the fascinating story of how NSA came to be, from its roots in World War II through the fall of the Berlin Wall. Along the way, he guides us through the fascinating challenges faced by cryptanalysts, and how they broke some of the most complicated codes of the twentieth century. With access to new documents, Budiansky shows where the agency succeeded and failed during the Cold War, but his account also offers crucial perspective for assessing NSA today in the wake of the Edward Snowden revelations. Budiansky shows how NSA’s obsession with recording every bit of data and decoding every signal is far from a new development; throughout its history the depth and breadth of the agency’s reach has resulted in both remarkable successes and destructive failures. Featuring a series of appendixes that explain the technical details of Soviet codes and how they were broken, this is a rich and riveting history of the underbelly of the Cold War, and an essential and timely read for all who seek to understand the origins of the modern NSA.
National Bestseller NPR Best Book of the Year “Not all superheroes wear capes, and Elizebeth Smith Friedman should be the subject of a future Wonder Woman movie.” —The New York Times Joining the ranks of Hidden Figures and In the Garden of Beasts, the incredible true story of the greatest codebreaking duo that ever lived, an American woman and her husband who invented the modern science of cryptology together and used it to confront the evils of their time, solving puzzles that unmasked Nazi spies and helped win World War II. In 1916, at the height of World War I, brilliant Shakespeare expert Elizebeth Smith went to work for an eccentric tycoon on his estate outside Chicago. The tycoon had close ties to the U.S. government, and he soon asked Elizebeth to apply her language skills to an exciting new venture: code-breaking. There she met the man who would become her husband, groundbreaking cryptologist William Friedman. Though she and Friedman are in many ways the "Adam and Eve" of the NSA, Elizebeth’s story, incredibly, has never been told. In The Woman Who Smashed Codes, Jason Fagone chronicles the life of this extraordinary woman, who played an integral role in our nation’s history for forty years. After World War I, Smith used her talents to catch gangsters and smugglers during Prohibition, then accepted a covert mission to discover and expose Nazi spy rings that were spreading like wildfire across South America, advancing ever closer to the United States. As World War II raged, Elizebeth fought a highly classified battle of wits against Hitler’s Reich, cracking multiple versions of the Enigma machine used by German spies. Meanwhile, inside an Army vault in Washington, William worked furiously to break Purple, the Japanese version of Enigma—and eventually succeeded, at a terrible cost to his personal life. Fagone unveils America’s code-breaking history through the prism of Smith’s life, bringing into focus the unforgettable events and colorful personalities that would help shape modern intelligence. Blending the lively pace and compelling detail that are the hallmarks of Erik Larson’s bestsellers with the atmosphere and intensity of The Imitation Game, The Woman Who Smashed Codes is page-turning popular history at its finest.
BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY | Finalist for the Los Angeles Times Book Prize “A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “An invaluable account . . . We owe Doudna several times over.” — Guardian
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