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Sample: "What does language do? Or, what does culture do? Language and culture are non-genetic mechanisms for increasing the number of qualities across individuals, and language and culture also increase the capacity for intraspecific assortative mating across individuals in the human species (by increasing the number of dissimilarities and categories of similarities across individuals in the human species). It is interesting to consider functional analogies amongst animals and plants: Birdsong and feather colors in bird species, and the colors and shapes of angiosperm flowering plant species play similar functions in these species, i.e., they increase the number and differentiation of characteristics across individual organisms, thus increasing the capacity for assortative mating across individual organisms in bird species (intraspecific assortative mating), and increasing the capacity for assortative mating across angiosperm species and insect, bee, and bird species (interspecific assortative mating).""
Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
During evolution there have been several major changes in the way genetic information is organized and transmitted from one generation to the next. These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance of multicellular plants and animals, the emergence of cooperation and of animal societies. This is the first book to discuss all these major transitions and their implications for our understanding of evolution.Clearly written and illustrated with many original diagrams, this book will be welcomed by students and researchers in the fields of evolutionary biology, ecology, and genetics.
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Popular Mechanics inspires, instructs and influences readers to help them master the modern world. Whether it’s practical DIY home-improvement tips, gadgets and digital technology, information on the newest cars or the latest breakthroughs in science -- PM is the ultimate guide to our high-tech lifestyle.
Plant architecture is the morphological manifestation of the genetic make-up of a plant at any one stage during its development. Application of accurate architectural models provides a wealth of information about living and extinct plants, especially in regard to growth pattern and development. The Evolution ofPlant Architecture brings together contributions from specialists in many different fields, including ecology, palaeobotany, systematics and evolution.