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Age-Related Macular Degeneration: Diagnosis and Treatment is written by two leading experts from Wills Eye Hospital. Covering the latest therapies and treatments developed in the last few years, this is a concise yet highly illustrated and practical text that guides the clinician through diagnosis and treatment of the leading cause of blindness in older Americans.
Showcases exudative and nonexudative AMD treatment techniques using argon and diode lasers, submacular and macular translocation surgery, photodynamic therapy, radiation, feeder vessel treatment, thermotherapy, and antiangiogenesis drugs. Includes 160 color illustrations. Showcases exudative and nonexudative AMD treatment techniques using argon and diode lasers, submacular and macular translocation surgery, photodynamic therapy, radiation, feeder vessel treatment, thermotherapy, and antiangiogenesis drugs. Age-Related Macular Degeneration examines newly developed treatments for CNV immune mechanisms of AMD histopathology of various stages of AMD epidemiology and risk factors for AMD, CNV, and geographic atrophy genetics of AMD risk reduction modalities ICG and OCT imaging clinical trials and research protocols quality of life assessments and the psychosocial aspects of AMD potential applications of a retinal prosthesis retinal pigment epithelium transplantation With 1425 references, Age-Related Macular Degeneration will benefit clinical ophthalmologists, pathologists, physiologists, and pharmacologists; optometrists; cell and molecular biologists and biochemists; retinal specialists; AMD researchers; and graduate and medical school students in these disciplines.
A consolidated view of a complex disorder, Age-Related Macular Degeneration, summarizes the latest evidence-based studies and translates these advancements into practical, actionable knowledge. This concise resource covers the fundamentals of age-related macular degeneration (AMD) diagnosis and treatment along with a modern definition of the disorder that acknowledges the range of presentations that ophthalmologists see in real practice. Offering practical, clinical guidance in addition to capturing new therapeutic approaches in the pipeline, this book is an essential reference for ophthalmologists, optometrists, and researchers. Takes a concise, yet comprehensive, approach to AMD, covering both basic science and clinical guidance. Features clinical guidelines on the diagnosis and treatment of AMD, including classification, signs/symptoms, imaging, and differential diagnosis in the pre-optical coherence tomography (OCT) and modern OCT eras. Presents up-to-date information on AMD therapies currently in the development pipeline and offers insights for the future of translational research. Explains molecular genetics and pathogenic events of AMD from both basic and clinical perspectives, which may help readers seek promising new therapeutic targets Contains more than 250 images, with multimodal imaging techniques that clearly demonstrate AMD pathophysiology and clinical pathology.
Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries.There have been rapid developments of therapies that today can halt or even reverse aspects of vision loss resulting from AMD among those most severely affected, and there is promise of future therapies that may prevent vision loss. This book provides an overview about AMD; an update on the current understanding of AMD, pathophysiology, the use of diagnostic tests, the management of both non-neovascular and neovascular AMD as well as future directions in treatment and its limitations. It also looks into the future with potential treatment options that are now under investigation in clinical trials.
This handbook is a compilation of major clinical trials in all subspecialties in the field of ophthalmology. Each trial is presented in a uniform manner, detailing the background and purpose of the study, design, number of subjects with inclusion and exclusion criteria, outcomes, then results and conclusions. Topics include glaucoma, cornea, diabetic retinopathy, age-related macular degeneration, retinal detachment, neuro-ophthalmology, ocular melanoma, and many more. Trials are arranged chronologically or in order of significance, with extensive referencing for further reading. ‘At a glance’ tables summarising each trial are also included. The previous edition of this comprehensive text (9789350907740) published in 2013.
Endorsed by the Macular Degeneration Foundation, this easy-to-read large type edition is the only book written for laymen that covers all of the latest scientific discoveries and promising research for age-related macular degeneration. Learn more about Visudyne (photodynamic therapy), laser therapy, nutrition and drug therapy. Dr. D'Amato covers alternative or complimentaty therapies such as acupuncture, meditation, microcurrent stimulation and more. Promising medical research initiatives are discussed. Macular Degeneration offers hope and practical advice for the 13-15 million Americans suffering from this disease.
The value of Age-Related Macular Degeneration has stood the test of time, but progress in both basic and clinical ophthalmology has been relentless, mandating the need for an updated book. This second edition focuses on the pathophysiology and the epidemiology of age-related macular degeneration (AMD), the clinical features and management of dry and wet AMD, imaging techniques, and medical therapy for both non-neovascular AMD and neovascular AMD. It describes both clinically validated and experimental therapies as well as rehabilitation technology, and presents strategies to prevent the progression of non-exudative AMD. Results from current clinical trials are also included. New chapters in this edition cover: Genetics and treatment Oxidative stress and its relation to the pathophysiology of AMD and CNV (choroidal neovascularization—a common symptom of wet AMD) Polypoidal choroidal vasculopathy Microperimetry and psychophysical testing and ways to track geographic atrophy progression Non-VEGF pathways Retinal stem cells
Circadian and Visual Neuroscience, Volume 273 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics including Optical set-ups, Psychophysics of Luminance and Color Vision, Psychophysics of non-visual photoreception PRC/IRC/DRC/Spectral Sensitivity, Circadian and visual photometry, Modelling (retina), Modelling (circadian), Techniques for examining vision at the cellular level, Advanced techniques for characterizing the world hyperspectrally, Circadian physiology in mice: Melanopsin, Circadian physiology in mice: Color and cones, Translational aspects of animal studies, Retinal clocks, Primate non-visual physiology, Light and mood in animal models, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research series Updated release includes the latest information on Circadian and Visual Neuroscience