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In compiling this textbook on the exciting novel imaging modality of PET/MRI, the editors have brought together a truly international group of experts in the field. The book is divided into two parts. The first part covers methodology and equipment and includes chapters on basic molecular medicine, contrast agents, MR attenuation and validation, and quantitative MRI and PET motion correction. The second part of the book focuses on clinical applications in oncology, cardiology, and neurology. Imaging of major neoplasms is covered in a series of individual chapters. Further chapters address functional and metabolic cardiovascular examinations and major central nervous system applications such as brain tumors and dementias. This book will be of interest to all radiologists and nuclear medicine physicians who wish to learn more about the latest developments in this important emerging imaging modality and its applications.
A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed. This book is intended for all health practitioners who need a concise reference and review of PET imaging indications, protocols and clinical applications. It will be useful to radiologists, nuclear medicine physicians, and clinicians who refer their patients to PET Centers for diagnostic imaging, including neurologists, neurosurgeons, psychiatrists, cardiologists, internists, and oncologists. Radiologic and nuclear medicine technologists, and physicians in training will also benefit from this work.
The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients. The future of Nuclear Medicine is bright, thanks to improved imaging resolution, new radiopharmaceuticals, and new diagnostic and therapeutic techniques and procedures.
This book is specifically designed to meet the needs of practicing radiologists by offering a practical, unified approach to PET-CT. It details how to effectively apply PET-CT in patient management. Written by radiologists who fully appreciate and understand both PET and CT, the book details an integrated understanding of PET-CT as a combined modality. Clinical topics include PET-CT of thoracic malignancies, melanoma, and breast cancer. In addition, the book reinforces fundamental concepts, such as the role of imaging diagnosis in disease management.
This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.
The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
Practical and clinically oriented, the third edition of Clinical Molecular Anatomic Imaging focuses on PET/CT, SPECT/CT, and PET/MR examinations – precisely the information you need to know. Ideal for clinical hybrid imaging users, it fully integrates all applications, allowing you to easily compare modalities and decide whether to use PET/CT, PET/MR, or SPECT/CT to solve a clinical dilemma. More than 1,600 high-quality illustrations document the use of integrated imaging and provide superb visual references for interpreting integrated imaging studies.
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Organised along an organ and systems basis, this comprehensive reference source covers all diagnostic and interventional imaging techniques and modalities in an integrated, correlative fashion.