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A contemporary guide to the diagnostic principles and practices of immunology and serology in the clinical laboratory.
A contemporary guide to the diagnostic principles and practices of immunology and serology in the clinical laboratory.
The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing. - Provides a unique mix of theory, practical advice and applications, with numerous examples - Offers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers - Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performancee - Provides valuable chapter updates, now available on www.immunoassayhandbook.com
The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more.
This reference on veterinary haematology and clinical chemistry is designed to be both comprehensive and practical. From basic principles and laboratory techniques to diagnostic evaluation, readers will find equally concise and clear coverage of both haematology and clinical chemistry for many domestic and exotic species. It also features numerous four-colour and black-and-white illustrations, coverage of avian and exotic haematology and an extensive use of case studies.
S.C. Rastogi, Formerly Professor Of Biological Sciences, B.I.T.S., Pilani, Has Vast Experience Of Teaching And Research Spanning More Than 40 Years. After His Training In Molecular Biology At Tata Institute Of Fundamental Research (Tifr), Mumbai, He Worked Constantly To Modernise Biology Courses At Bits. He Has Taught And Supervised Doctoral Research In Computer Applications In Molecular Biology, Enzyme Biotechnology And Physiology, And Has Successfully Completed Several Research Projects. He Has Edited Many Proceedings Of Scientific Symposia And Authored Research Papers And Books In The Field Of Bioinformatics, Biochemistry, Physiology, Molecular Biology And Biotechnology. As A Biologist Of Repute, And Accredited With Many Educational Innovations, He Has Been A Constant Participant In Course Development Work At Bits And Otheruniversities.
If you're looking to succeed in today's modern laboratory environment, then you need the insightful guidance found in Immunology & Serology in Laboratory Medicine, 6th Edition. Continuing to set the standard for comprehensive coverage of immunology, this must-have resource covers everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. As with previous editions, trusted author, teacher and former university program director, Mary Louise Turgeon helps you build a solid foundation of knowledge and skills by taking you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you will encounter in the lab. And now with a new full-color design, additional case studies, wealth of content updates, and new features, there's never been more reason to rely on Turgeon to stretch your critical thinking skills and fully prepare for success in the clinical lab. Comprehensive immunology coverage features the latest illustrations, photographs and summary tables to help clarify various concepts and information visually. Emphasis on critical thinking utilizes case studies to challenge readers to apply their knowledge to practice. Procedural protocols move readers from immunology theory to practical aspects of the clinical lab. Chapter highlights and review questions at the end of each chapter offer opportunities for review and self-assessment. Learning objectives and key terms at the beginning of each chapter outline the important vocabulary, information, and concepts found in the chapter. Glossary at the end of the book provides a quick reference to key terms and definitions. NEW! Full color diagrams and micrographs increases comprehension and gives readers a much better sense of what they will encounter in the lab. NEW! Updated content on vaccines, tumor immunology, transplant rejection, immunotherapies, instrumentation for molecular diagnosis, the immune response, and more ensures readers are prepared for immunology in today's clinical lab. NEW! Additional case studies allow readers to apply knowledge to real world situations and stretch their critical thinking skills. NEW! Reformatted chapter review questions reflect the multiple choice styles encountered on exams.
Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.