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The authors in this issue will provide state-of-the-art reviews on the use of probiotics in care of the gastroenterologic system. Articles are devoted to probiotics as treatment for IBD, chronic diarrhea, C. difficile colitis, functional bowel disease, allergic disorders, necrotizing enterocolitis, and obesity. Other articles examine the safety of probiotics, fecal biotherapy, and molecular assessment of intestinal microflora.
This issue discusses the applications of probiotics in gastroenterology and will focus on not only the clinical applications of the bacteria themselves but also the function of the bacteria on the gastrointestinal tract. In addition, attention is given to the application of probiotics in the pediatric population as well as to those with inflammatory bowel disease.
Dr. Quigley has created a must-have reference on the gut microbiome for the practicing gastroenterologist. A leader in the field of human physiology and digestive disorders, he has laid out the basics on this increasingly important topic, devoting articles to the organization and biology of the human gut microbiome as well as its diagnostic potential. Top international authors have presented articles that discuss the intersection of the gut microbiome and diet and the gut-brain axis. Clinical implications of the gut microbiome are discussed with disease states like IBD, GI cancer, and liver diseases. Finally, the issue ends with the cutting-edge clinical innovation of fecal microbial transplantation. This issue bridges the gap between science and clinical practice and should be an important reference to practicing gastroenterologists.
Dr. Hammer has assembled a international list of authors who fully update the topic of chronic diarrhea, from examining the causes of diarrhea (and the appropriate treatments) to various diagnostic tools. Among the topics covered are bacterial flora as a cause or treatment, the value of fecal analysis in the evaluation, circulating secretagogues, functional diarrhea, celiac disease, chronic inflammatory diseases, diarrhea as a symptom of food intolerance, immunosuppression and immune-deficiency, and chronic diarrhea in the developing world.
The Guest Editors have focused on methods of diagnosing and evaluating IBD to help guide optimal treatment to maximize clinical outcomes and minimize risks. Authors have provided state-of-the-art updates with practical information/guidelines/algorithms and cutting-edge data for incorporation into practice. The first set of articles deals with endoscopy: its role in diagnosis and monitoring IBD; the growing importance of chromoendoscopy in IBD surveillance exams; assessment of post-operative recurrence; and finally the emerging role of capsule endoscopy. The second section focuses on specific scenarios that IBD physicians encounter frequently: health maintenance in IBD focusing on proper vaccinations; the growing problem of Clostridium difficile in IBD; assessment of pouch problems; optimal evaluation of perianal disease; the state of the art in using thiopurines including use of allopurinol to optimize metabolites and optimizing the use of infliximab by measuring levels and antibodies to infliximab; factors to consider in choosing monotherapy versus combination therapy and communication of risk/benefit to patients; and finally disability assessment in IBD. The third and final section highlights noninvasive methods to evaluate IBD: clinical predictors of aggressive or disabling disease; the evolving role of specific antibodies in diagnosing, subtyping and most recently prognosticating in IBD; stool markers (calproctectin and lactoferrin) for evaluating and monitoring IBD; the growing role of imaging modalities with emphasis on MR enterography and CT enterography; and finally, the genetics of IBD and the potential role of genetic testing in the diagnosis/prognosis and tailoring of therapy.
Dr. Kahi has assembled top experts to provide clinically focused articles on colonoscopy and polypectomy. The issue is divided into sections devote to Technique Fundamentals, Advances in Technique, Technology, Neoplasia Detection, Quality and Outcomes, and The Future. Everyone from early-career gastroenteorlogists to those late in their career should find this edition to be very valuable.
Esophageal diseases are amongst the most common gastrointestinal illnesses encountered by both the gastroenterologist as well as the primary care physician. Gastroesophageal reflux symptoms affect 20% of adult Americans on a weekly or more frequent basis, and Barrett’s esophagus, a pre-cancerous lesion of the distal esophagus associated with chronic GERD, is prevalent in 2-6% of the adult population. Additionally, there have been remarkable advances in the care of esophageal diseases in the last several years, with the development of new imaging modalities, new physiological tests, and promising data emerging with respect to biomarkers for esophageal neoplasia. A relatively new clinical entity, eosinophilic esophagitis, is being characterized in the literature, and the ubiquity of this condition is now recognized. Given the dynamic nature of this area, the strides being made in esophageal diseases, and the importance of these diseases to clinicians practicing both subspecialty and general medicine, a volume dedicated to esophageal diseases is timely and necessary. The goals of this work are to familiarize clinicians with advances in care of patients with esophageal disorders, and to update them on new trends in epidemiology and outcomes of these diseases.
Gastric cancer is the second most common cause of cancer mortality worldwide. Although the incidence of gastric cancer has declined over the past century in the United States, it remains one of the most common gastrointestinal neoplasms, particularly in immigrants and the socio-economically deprived. Recent years have seen major advances in our understanding of the pathogenesis of gastric cancer (especially regarding the importance of Helicobacter pylori and its associated inflammatory response) and the emergence of adjuvant oncologic therapies of proven benefit for advanced cases, in addition to surgery. As for gastric adenocarcinoma, elucidation of the underlying biology and molecular pathogenesis has led to much progress in the management of two other malignant gastric neoplasms, gastrointestinal stromal tumors and marginal zone B-cell (“MALT ) lymphomas. This monograph highlights these developments, presenting an updated overview of gastric cancer that will be of interest to all practicing gastroenterologists.
Probiotics: A Clinical Guide is one of the first books on the market to present current and evidence-based recommendations for primary care providers and gastroenterologists on the use of probiotics as a way to treat specific diseases and disorders. Why you will want Probiotics: A Clinical Guide: Unique focus on the clinical use of probiotics in a wide variety of diseases Comprehensive review of the science behind probiotics and probiotic products In-depth review of current literature for specific diseases or disorders Recommendations of the use of probiotics is supported by evidence-based clinical trials Each chapter includes a table that outlines the exact probiotic organisms and dosages that are the most efficacious A glance at what is inside Probiotics: A Clinical Guide: Basic Physiology Intestinal microecology; stimulating the immune response, nutrients to nourish the organism, role in fermentation and metabolism, and much more... Use in Clinical Medicine Probiotics in children, adult infectious diarrhea, surgical infections, allergic disease, ulcerative colitis, crohn’s disease, liver disease, and more... Probiotics: A Clinical Guide by Dr. Martin Floch & Dr. Adam Kim is a ground-breaking book that will serve as a valuable reference and clinical guide for gastroenterologists, internists, family practitioners, nurse practitioners, and physician assistants.
Dr. Van Dam is an internationally recognized leader in gastroenterology and has been a leader in advances in intervedntional endoscopy. He brings this expertise to the topic of management of benign and malignant pancreatic disease and has selected top experts in the field to provide state-of-the-art clinical information to gastroenterologists. The modern management treatise of each article addresses current diagnostics as well as medical management. Seven articles are devoted to pancreatic cancer and span medical management, surgial mangament, radiologic imaging, endoscopic diagnosis, palliation, and screening. Other important topics addressed are pancreatic transplantation, pancreatic cystic neoplasms, acute and chronic pancreatitis, and autoimmune pancreatitis.