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Practical text provides quick access to key diagnostic features of each virus encountered in clinical practice and their management.
The explosion in clinical testing has been especially rapid in virology, where emerging viruses and growing numbers of viral infections are driving advances. The Guide to Clinical and Diagnostic Virology offers a digestible view of the breadth and depth of information related to clinical virology, providing a practical, working knowledge of the wide array of viruses that cause human disease. Introductory chapters cover the basics of clinical virology and laboratory diagnosis of infections, including virus structure, life cycle, transmission, taxonomy, specimen types and handling, and a comparison of assays used for detection. Detailed sections on important topics include Viral pathogens and their clinical presentations Diagnostic assays and techniques, including culture-based, immunological, and molecular Prevention and management of viral infections, with guidance on biosafety, vaccines, and antiviral therapies The regulatory environment for laboratory testing, including regulatory requirements and assay performance and interpretation Critical concepts are carefully curated and concisely summarized and presented with detailed illustrations that aid comprehension, along with important highlights and helpful hints. These features, plus question sections that reinforce significant ideas and key concepts, make this an invaluable text for anyone looking for an accessible route through clinical and diagnostic virology. Laboratory technologists, medical students, infectious disease and microbiology fellows, pathology residents, researchers, and everyone involved with viruses in the clinical setting will find the Guide to Clinical and Diagnostic Virology an excellent text as well as companion to clinical virology references.
The essential reference of clinical virology Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses. Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections: Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections. Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.
A collection of cutting-edge techniques for detecting most of the major viruses that afflict mankind, including influenza, hepatitis, herpes, polio, mumps, HIV, and many more. The techniques are well-tested, easily reproducible, and readily employ all the new technologies-PCR, RIA, ELISA, and latex-agglutination-that have revolutionized the field. These methods not only make it possible to do the necessary analysis in hours instead of days, but can also be automated in a laboratory havng only low levels of biological containment. Frequently, the protocols for viruses causing human diseases can be adapted to similar viruses of veterinary importance. Through its state-of-the-art methods a physician can, for the first time, determine early in a viral infection which antiviral drug should be used and minimize the period of treatment to avoid unnecessary side effects.
Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control
The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates. This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included. There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.
This generously illustrated book, the fourth edition of the highly acclaimed Diagnostic Virology, is a handbook for the recognition and characterization of virus-induced cellular changes seen by light microscopy, as well as virus morphology seen by electron microscopy. The authors cover all aspects of the subject, from specimen collection and laboratory safety to virus isolation and identification and cell culture. This edition includes a new chapter on the human retroviruses, especially relevant since the onset of the AIDS epidemic, and expands the chapters on the arboviruses and hepatitis viruses.
This Second Edition of A Practical Guide to Clinical Virology is a practical, highly illustrated, quick reference guide to clinical virology. It brings together the essentials of the subject in a entertaining and informative style, describing in turn the clinical features, the symptoms and signs of each of the viral diseases, as well as summarising the epidemiology, laboratory diagnosis and therapy in each case. This book also includes general chapters on classification, diagnosis of infection, antiviral drugs, vaccines and different clinical syndromes. Key Features: Chapter summaries for quick reference Cartoon illustrations Comprehensive coverage Clear and concise format Each chapter is easy to read and well organised, ensuring that this is an invaluable textbook for all medical, biomedical, microbiology and applied biology students. In addition, it provides an excellent reference for nurses, occupational health and infection control departments, public health and diagnostic laboratories.
Heres a practical resource on the diagnosis of viral pathogens. Organized by clinical syndrome, it guides readers from presenting signs through discussions of which viruses might be involved to a definitive laboratory diagnosis. This comprehensive reference examines both common and rare viral diseasesand integrates traditional techniques in diagnostic virology with the latest molecular tests. Examines how to select, procure, and handle specimens safely and effectively. Addresses the latest advances in antiviral susceptibility testing. Details how to approach a patient infected with a previously undiscovered viral agent. Features coverage of infections that occur in travelers such as dengue fever, Rift Valley fever, and hantavirus ... complete discussions of common and unusual serotypes of HIV as well as other human retroviruses such as HTLV-I and HTLV-II ... and more. Helps readers identify cytomegalovirus infections in immunocompro-mised patientsincluding solid organ transplant recipients, bone marrow transplant recipients, and people with HIV/AIDS. Reviews all laboratory methods used in diagnostic virology.