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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.
In this book the author, an investigative journalist, traces the social history of marijuana from its origins to its emergence in the 1960s as a defining force in an ongoing culture war. He describes how the illicit marijuana subculture overcame government opposition and morphed into a multibillion-dollar industry. In 1996, Californians voted to legalize marijuana for medicinal purposes. Similar laws have followed in several other states, but not without antagonistic responses from federal, state, and local law enforcement. The author draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape: medical researchers have developed promising treatments for cancer, heart disease, Alzheimer's, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures. This book is an examination of the medical, recreational, scientific, and economic dimensions of the world's most controversial plant.
In this thrilling romantic suspense, smokejumper Alexia Allen returns home to face her past only to find a long-buried secret that threatens her life.
From the leading authority on marijuana—a man who has served as White House advisor on drugs to three different administrations and who NBC News once called “the prodigy of drug politics"—comes the remarkable and shocking exposé about how 21st century pot, today’s new and highly potent form of the drug, is on the rise, spreading rapidly across America by an industry intent on putting rising profits over public health. Smokescreen: What the Marijuana Industry Doesn't Want You to Know examines the inside story behind the headlines, containing accounts from Sabet’s time in the Obama administration to stunning revelations from whistleblowers speaking out for the first time. What it finds is how the marijuana industry is running rampant without proper oversight, leaving Americans’ health seriously at risk. Included are interviews with industry insiders who reveal the hidden dangers of a product they had once worshipped. Also contained in these pages are insights from a major underground-market dealer who admits that legalization is hastening the growth of the illicit drug trade. And more to the heart of the issue are the tragic stories of those who have suffered and died as a result of marijuana use, and in many cases, as a result of its mischaracterization. Readers will learn how power brokers worked behind the scenes to market marijuana as a miracle plant in order to help it gain widespread acceptance and to set the stage for the lucrative expansion of recreational pot. The author of this compelling first-person narrative leading the national fight against the legalization of cannabis through his nonprofit, Smart Approaches to Marijuana (aka SAM) is Kevin Sabet. As a policy advisor to everyone from county health commissioners to Pope Francis, and a frequent public speaker on television, radio and through other media outlets, his analysis is consistently relied upon by those who recognize what’s at stake as marijuana lobbyists downplay the risks of massive commercialization. A book several years in the making, filled with vivid characters and informed by hundreds of interviews and scores of confidential documents, Sabet's Smokescreen lays bare the unvarnished truth about marijuana in America.
Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.
“A humorous and informative trip through the drug’s various medicinal compounds, a timeline of the its history, and recipes that take you beyond the standard pot brownie—with pro tips from cannabis-friendly celebrities sprinkled throughout.”—Vanity Fair Once literally demonized as “the Devil's lettuce,” and linked to all manner of deviant behavior by the establishment's shameless anti-marijuana propaganda campaigns, cannabis sativa has lately been enjoying a long-overdue Renaissance. So now that the squares at long last seem ready to rethink pot's place in polite society, how, exactly, can members of this vibrant, innovative, life-affirming culture proudly and properly emerge from the underground—without forgetting our roots, or losing our cool? In How to Smoke Pot (Properly), VICE weed columnist and former High Times editor David Bienenstock charts the course for this bold, new, post-prohibition world. With plenty of stops along the way for "pro tips" from friends in high places, including cannabis celebrities and thought leaders of the marijuana movement, readers will learn everything from the basics of blazing, to how Mary Jane makes humans more creative and collaborative, nurtures empathy, catalyzes epiphanies, enhances life's pleasures, promotes meaningful social bonds, facilitates cross-cultural understanding, and offers a far safer alternative to both alcohol and many pharmaceutical drugs. You'll follow the herb's natural lifecycle from farm to pipe, explore cannabis customs, culture and travel, and discover how to best utilize and appreciate a plant that's at once a lifesaving medicine, an incredibly nutritious food, an amazingly useful industrial crop, and a truly renewable energy source. You'll even get funny and informative answers to burning questions ranging from: How can I land a legal pot job? to Should I eat a weed cookie before boarding the plane? In two-color, with charts and illustrations throughout, How to Smoke Pot (Properly) is truly a modern guide to this most revered herb.
A guide to using smoke and scents to create a positive, healing home for you and your family. Aromatherapist and long-time herbalist Amy Blackthorn offers the essential tools for creating sacred space—a safe space free of negative energies—using herbs, incense, smoke, and other practices. “No matter your faith,” writes Amy Blackthorn, “practicing with sacred smoke is a powerful way to make your intentions known and support change in your life. . . . An argument between friends can be hashed out over calming lavender smoke. A home can find prosperity in the embrace of burning clove powder. Space can be consecrated with the grace and devotional power of cedar. Every ritual or occasion can be tailored to the language of scent.” Written in an accessible style, free of jargon, Sacred Smoke has everything you need to know to get started on your practice of purification and cleansing, including: The importance of self-care How to keep your home and family safe How to protect your home while you are away Adding crystals to your cleansing practice Using essential herbs and recipes for creating cleansing smoke Sacred Smoke is an essential guide for anyone seeking to practice the ritual use of cleansing and clearing to protect and heal themselves, their home, and their family.
The nation has made tremendous progress in reducing tobacco use during the past 40 years. Despite extensive knowledge about successful interventions, however, approximately one-quarter of American adults still smoke. Tobacco-related illnesses and death place a huge burden on our society. Ending the Tobacco Problem generates a blueprint for the nation in the struggle to reduce tobacco use. The report reviews effective prevention and treatment interventions and considers a set of new tobacco control policies for adoption by federal and state governments. Carefully constructed with two distinct parts, the book first provides background information on the history and nature of tobacco use, developing the context for the policy blueprint proposed in the second half of the report. The report documents the extraordinary growth of tobacco use during the first half of the 20th century as well as its subsequent reversal in the mid-1960s (in the wake of findings from the Surgeon General). It also reviews the addictive properties of nicotine, delving into the factors that make it so difficult for people to quit and examines recent trends in tobacco use. In addition, an overview of the development of governmental and nongovernmental tobacco control efforts is provided. After reviewing the ethical grounding of tobacco control, the second half of the book sets forth to present a blueprint for ending the tobacco problem. The book offers broad-reaching recommendations targeting federal, state, local, nonprofit and for-profit entities. This book also identifies the benefits to society when fully implementing effective tobacco control interventions and policies.