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This review of the control of circulation during hibernation begins with a general description of hibernation as it occurs in various groups of mammals and outlines the difficulties in the physiological study of hibernation. There fol lows a more detailed description of the three phases of hibernation - entering hibernation, in deep hibernation, and waking from the hiber nating state. The bulk of the review concerns research on rodents, which have been the most intensively studied of the animals which hiber nate. It is emphasized that hibernation, at least in this groups, is a precisely controlled series of physiological changes in which the animal maintains a homeostatic condition at all times in spite of profound changes in body temperature.
Hibernation and Torpor in Mammals and Birds explores the physiological factors that control hibernation and torpor in birds and mammals. This text covers topics ranging from metabolism in hibernation to the role of endocrines, respiration and acid-base state in hibernation, and theories of hibernation. This book is comprised of 14 chapters and begins with an overview of some clear-cut definitions and why mammals and birds hibernate. The reader is then introduced to the variations from euthermia that have been observed among birds and mammals. To give some structure to this listing, the approach is phylogenetic, starting with the birds and proceeding through the primitive to the more advanced mammals. Subsequent chapters explains the process of entering hibernation and the hibernating state, itself; capability of a species in natural hibernation to arouse from that state using self-generated heat; physiological changes at the start of a spontaneous arousal; and physiological mechanisms underlying the ability of hibernators to rewarm. Consideration is also given to intermediary metabolism in hibernation, cold adaptation of metabolism in hibernators, and the response of hibernators to various extrinsic influences such as neoplastic growth, radiation injury, and parasitism and symbionts. This book will be of interest to students and researchers in fields ranging from zoology to physiology and biophysics.
This book gives an up-to-date account of the current knowledge of cold adaptation in animals, including phenomena like hibernation, daily torpor, thermoregulation and thermogenesis, metabolic regulation, freeze tolerance, anaerobiosis, metabolic depression and related processes. For the next four years - until the 12th International Hibernation Symposium - it will serve as a state-of-the-art reference source for every scientist and graduate student working in these areas of physiology and zoology.
This book presents a state-of-the-art summary of the applications of low temperature to clinical situations, together with details of the underlying principles of biology. It provides specific information for the clinicians and research workers in a number of areas of current interest and attempts to provide a unifying theme of cryobiology of interest and value to those researching a clinical problem. Specific topics discussed include the effects of low temperatures on mammalian systems in the absence of ice and how the changes can be modulated to achieve desired results; low temperature storage of tissues and organs for transplantation in the liquid state; the effects of whole body hypothermia in man and how it relates to mammal hibernation; problems associated with ice formation and the subsequent freezing of cells and tissues; cryopreservation of blood cells, reproductive cells, and tissues, such as the skin and cornea. Other interesting issues featured include the developments in cryopreservation of large, highly-organized structures and the destructive powers of ice formation in cryosurgery of diseased tissues.
The bibliography consists of over 2,100 references directly impinging upon natural mammalian hibernation, including a few references to birds and potential hibernators. A cross-referenced subject matter index makes it possible to locate with relative ease articles dealing with specific features of hibernation. The material was assembled over a number of years by detailed examination of library holdings, review literature, abstracting journals, The Zoological Record, B.A.S.I.C., and individual journals, and with the cooperation of fellow researchers in the field of natural mammalian hibernation. The assembled references were checked for their applicability for inclusion in this bibliography, alphabetized by author, and numbered for cross reference indexing. The parameters of the initial charge for making this bibliography have eliminated references to poikilothermous animals and most references to hypothermia, and have been the guidelines used to reduce some 7,000 references to the approximately one-third which finally comprise this bibliography.
Lists citations with abstracts for aerospace related reports obtained from world wide sources and announces documents that have recently been entered into the NASA Scientific and Technical Information Database.