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Coronary heart disease (CHD) remains a major cause of human mortality and morbidity worldwide. Classical risk factors for atherosclerosis fail to account fully for the wide variations in CHD prevalence and/or severity between differing populations. The search for hitherto unrecognised risk factors has recently focused on the potential role of chronic inflammation and common infections. Chronic Infection, Chlamydia and Coronary Heart Disease is the first book to review the wealth of evidence linking various infective agents with CHD, focusing particularly on the proposed pathogenetic role of the main candidate microorganism, Chlamydia pneumoniae. Written by two leading investigators in the field, the book provides a concise, clearly written and up-to-date account of the diverse lines of evidence - seroepidemiological, pathological, animal and in vitro data and clinical antibiotic trials. The possibility of an infective basis to atherosclerosis and CHD has already attracted much scientific interest. Chronic Infection, Chlamydia and Coronary Heart Disease highlights the key published works on the topic, and concludes with information on existing, ongoing, and future lines of enquiry.
Infectious agents have been recognized to involve the heart and vascular system for well over a century. Traditional concepts and teachings of their involvement in the pathogenesis of disease have been by a few established mechanisms. Since the last decade of the 20th century there has been renewed interest in the medical and public media on infectious diseases affecting the cardiovascular and cerebrovascular systems, through their relationship with the development of acceleration of atherosclerosis. This volume highlights and reviews new perspectives of infections on the cardiovascular system as never before. It is a truly valuable resource for scientists, researchers, residents, and fellows in the fields of infectious disease, cardiology, and microbiology.
In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.
Perhaps you've read about the Heart Attack Germ in Reader's Digest. Or you may have seen the story about it on Dateline NBC. But The Heart Attack Germ is the first and only book that reveals the full story behind this astonishing and revolutionary medical breakthrough. A germ named Chlamydia pneumoniae has been identified by medical researchers the world over as the Heart Attack Germ. People infected by this germ are at a significantly increased risk for stroke, heart attack and other cardiovascular problems, including the symptoms of Alzheimer's disease. Several other common bacteria and viruses have also been associated with an increased risk of stroke and heart attack. All of these germs are contagious and easily transmitted from person to person. In fact, the odds are that you've already been infected by one or more of the germs of cardiovascular disease. The discovery of the Heart Attack Germ has produced improved treatments that, for the first time, attack the underlying cause of cardiovascular trouble. Vividly written and illustrated, The Heart Attack Germ will show you how to dramatically reduce your risk of stroke, heart attack and the symptoms of Alzheimer's: safely, painlessly, inexpensively and without surgery.
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs
In the last ten years, major strides have been made in defining the presence and role of inflammation in atherosclerosis as well as in injury to the tissues that occurs after episodes of ischemia and reperfusion. In sixteen chapters, written by world-renowned individuals from different countries, the role of inflammation and different mediators in the pathogenesis of atherosclerosis is presented. The significance of inflammation and possible therapeutic implications is also described in depth. This book is of great interest for a wide range of physicians, researchers, and scientists who may want to study more and develop the concept of inflammation and atherosclerosis.
Helicobacter pylori: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Helicobacter pylori in a concise format. The editors have built Helicobacter pylori: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Helicobacter pylori in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Helicobacter pylori: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Despite remarkable progress in fighting against myocardial infarction, the thrombotic complications of the coronary artery are still a significant cause of morbidity and mortality worldwide. Treatment options for arterial thrombosis include either relatively old drugs such as streptokinase, and newer agents that are either approved by the FDA or still undergoing clinical trials. These options make some room for questions that lead to a conclusion for the best combination of drugs for treating patients with acute coronary syndromes. The handbook combines available information from basic hematology, cardiology and clinical trials and presents practical bed-side solutions for clinicians working with patients suffering from acute coronary syndromes. Readers will learn about the pathogenesis and diagnosis of thrombosis, thrombogenesis and fibrinolysis. Newer antithrombotic agents, cardiac diseases, venous thromboembolism are also covered. Health professionals will have quick access to relevant and organized information which also includes visual and tabular guides as well as some recommendations from professional societies.