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In the nineteenth century, tens of thousands of women died each year from childbed fever. The Carters describe birthing conditions and medical practices in Vienna during the time when young Semmelweis began to work in a maternity clinic there. He discovered that childbed fever arose because medical personnel did not wash adequately after dissecting corpses before doing vaginal examinations of women in labor. After he required students to disinfect themselves, the mortality rate immediately dropped. However, Semmelweis's views were not accepted by the senior physicians who believed the disease was due to a variety of causes. After strident attempts to persuade skeptics, Semmelweis was committed to a Viennese insane asylum where he died at age 42, possibly from beatings by asylum guards. Childbed fever, now called puerperal infection, continues to be a leading cause of maternal mortality, in spite of the best efforts of modern physicians.
Childbed fever was by the far the most common cause of deaths associated with childbirth up to the Second World War throughout Britain and Europe. Otherwise known as puerperal fever, it was an infection which followed childbirth and caused thousands of miserable and agonising deaths every year. This book provides the first comprehensive account of this tragic disease from its recognition in the eighteenth century up to the second half of the twentieth century. Examining this within a broad history of infective diseases, the author goes on to explore ideas from past debates about the nature of infectious diseases and contagion, the discovery of bacteria and antisepsis, and charts the complicated path which led to the discovery of antibiotics. The large majority of deaths from puerperal fever were due to one micro-organism known as Streptococcus pyogenes, and the last chapter presents valuable new ideas on the nature and epidemiology of streptococcal disease up to the present day.
Semmelweis's exposure to the childbed fever was concurrent with his appointment to the Vienna maternity hospital in 1846. Like many similar hospitals and clinics in the major cities of nineteenth-century Europe and America, where death rates from the illness sometimes climbed as high as 40 percent of admitted patients, the Viennese wards were ravaged by the fever. Intensely troubled by the tragic and baffling loss of so many young mothers, Semmelweis sought answers. The Etiology was testimony to his success. Based on overwhelming personal evidence, it constituted a classic description of a disease, its causes, and its prevention. It also allowed a necessary response to the obstetrician's already vocal, rabid, and perhaps predictable critics. For Semmelweis's central thesis was a startling one - the fever, he correctly surmised, was caused not by epidemic or endemic influences but by unsterilized and thus often contaminated hands of the attending physicians themselves.
The fascinating story of Ignaz Semmelweis, a nineteenth-century obstetrician ostracized for his strident advocacy of disinfection as a way to prevent childbed fever In Genius Belabored: Childbed Fever and the Tragic Life of Ignaz Semmelweis, Theodore G. Obenchain traces the life story of a nineteenth-century Hungarian obstetrician who was shunned and marginalized by the medical establishment for advancing a far-sighted but unorthodox solution to the appalling mortality rates that plagued new mothers of the day. In engrossing detail, Obenchain recreates for readers the sights, smells, and activities within a hospital of that day. In an era before the acceptance of modern germ science, physicians saw little need for cleanliness or hygiene. As a consequence, antiseptic measures were lax and rudimentary. Especially vulnerable to contamination were new mothers, who frequently contracted and died from childbed fever (puerperal fever). Genius Belabored follows Semmelweis’s awakening to the insight that many of these deaths could be avoided with basic antiseptic measures like hand washing. The medical establishment, intellectually unprepared for Semmelweis’s prescient hypothesis, rejected it for a number of reasons. It was unorthodox and went against the lingering Christian tradition that the dangers of childbirth were inherent to the lives of women. Complicating matters, colleagues did not consider Semmelweis an easy physician to work with. His peers described him as strange and eccentric. Obenchain offers an empathetic and insightful argument that Semmelweis suffered from bipolar disorder and illuminates how his colleagues, however dedicated to empirical science they might have been, misjudged Semmelweis’s methods based upon ignorance and their emotional discomfort with him. In Genius Belabored, Obenchain identifies Semmelweis’s rightful place in the pantheon of scientists and physicians whose discoveries have saved the lives of millions. Obenchain’s biography of Semmelweis offers unique insights into the practice of medicine and the mindsets of physicians working in the premodern era. This fascinating study offers much of interest to general readers as well as those interested in germ theory, the history of medicine and obstetrics, or anyone wishing to better understand the trajectory of modern medicine.
A narrative of one of the key turning points in medical history.
Oliver Wendell Holmes Sr., (1809-1894) was a physician by profession but achieved fame as a writer. He was one of the best regarded American poets of the 19th century. In 1833 Holmes attended the famed Ecole de Medecine in Paris. He pursued his medical studies in the Parisian hospital system. He first attained national prominence with his poem Old Ironsides. One of his most popular works was The Autocrat of the Breakfast Table (1857). He was one of the five members of the group known as the Fireside Poets. He contributed poems and essays to the Atlantic Monthly from its inception, and also published novels. Holmes is also known for his writing of several beautiful hymns. In 1846, Holmes coined the word anesthesia. He also developed the popular model of the stereoscope. Amongst his other works are Elsie Venner (1861), The Guardian Angel (1867), The Poet at the Breakfast-Table (1872), John Lothrop Motley: A Memoir (1879), Medical Essays (1883), A Mortal Antipathy: First Opening of the New Portfolio (1885) and Over the Teacups (1891).
An argument that what makes science distinctive is its emphasis on evidence and scientists' willingness to change theories on the basis of new evidence. Attacks on science have become commonplace. Claims that climate change isn't settled science, that evolution is “only a theory,” and that scientists are conspiring to keep the truth about vaccines from the public are staples of some politicians' rhetorical repertoire. Defenders of science often point to its discoveries (penicillin! relativity!) without explaining exactly why scientific claims are superior. In this book, Lee McIntyre argues that what distinguishes science from its rivals is what he calls “the scientific attitude”—caring about evidence and being willing to change theories on the basis of new evidence. The history of science is littered with theories that were scientific but turned out to be wrong; the scientific attitude reveals why even a failed theory can help us to understand what is special about science. McIntyre offers examples that illustrate both scientific success (a reduction in childbed fever in the nineteenth century) and failure (the flawed “discovery” of cold fusion in the twentieth century). He describes the transformation of medicine from a practice based largely on hunches into a science based on evidence; considers scientific fraud; examines the positions of ideology-driven denialists, pseudoscientists, and “skeptics” who reject scientific findings; and argues that social science, no less than natural science, should embrace the scientific attitude. McIntyre argues that the scientific attitude—the grounding of science in evidence—offers a uniquely powerful tool in the defense of science.
A groundbreaking look at the connection between germs and mental illness, and how we can protect ourselves. Is it possible to catch autism or OCD the same way we catch the flu? Can a child's contact with cat litter lead to schizophrenia? In her eye-opening new book, National Book Critics Circle Award-winning author Harriet Washington reveals that we can in fact "catch" mental illness. In Infectious Madness, Washington presents the new germ theory, which posits not only that many instances of Alzheimer's, OCD, and schizophrenia are caused by viruses, prions, and bacteria, but also that with antibiotics, vaccinations, and other strategies, these cases can be easily prevented or treated. Packed with cutting-edge research and tantalizing mysteries, Infectious Madness is rich in science, characters, and practical advice on how to protect yourself and your children from exposure to infectious threats that could sabotage your mental and physical health.
The life and work of Ignaz Semmelweis is among the most engaging and moving stories in the history of science. Childbed Fever makes the Semmelweis story available to a general audience, while placing his life, and his discovery, in the context of his times. In 1846 Vienna, as what would now be called a head resident of obstetrics, Semmelweis confronted the terrible reality of childbed fever, which killed prodigious numbers of women throughout Europe and America. In May 1847 Semmelweis was struck by the realization that, in his clinic, these women had probably been infected by the decaying remains of human tissue. He believed that infection occurred because medical personnel did not wash their hands thoroughly after conducting autopsies in the morgue. He immediately began requiring everyone working in his clinic to wash their hands in a chlorine solution. The mortality rate fell to about one percent. While everyone at the time rejected his account of the cause of the disease because his theory was fundamentally inconsistent with existing medical beliefs about how diseases were transmitted, in time Semmelweis was proven to be correct. His work led to the adoption of a new way of thinking about disease, thus helping to create an entirely new theory - the etiological standpoint - that still dominates medicine today.