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The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) addresses classification and labelling of chemicals by types of hazards. It provides the basis for worldwide harmonization of rules and regulations on chemicals and aims at enhancing the protection of human health and the environment during their handling, transport and use by ensuring that the information about their physical, health and environmental hazards is available. The sixth revised edition includes, inter alia, a new hazard class for desensitized explosives and a new hazard category for pyrophoric gases; miscellaneous amendments intended to further clarify the criteria for some hazard classes (explosives, specific target organ toxicity following single exposure, aspiration hazard, and hazardous to the aquatic environment) and to complement the information to be included in section 9 of the Safety Data Sheet; revised and further rationalized precautionary statements; and an example of labelling of a small packaging in Annex 7.

Chemical Harmonization

United States. Congress. Senate. Committee on Commerce, Science, and Transportation. Subcommittee on Consumer Affairs, Foreign Commerce, and Tourism

Published: 2004

Total Pages: 68


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The GHS addresses classification of chemicals by types of hazard and proposes harmonized hazard communication elements, including labels and safety data sheets. It aims at ensuring that information on physical hazards and toxicity from chemicals be available in order to enhance the protection of human health and the environment during the handling, transport and use of these chemicals. The GHS also provides a basis for harmonization of rules and regulations on chemicals at national, regional and worldwide level, an important factor also for trade facilitation. This fifth revised edition of the GHS contains various new or revised provisions concerning, inter alia, new hazard categories for chemically unstable gases and non-flammable aerosols; further rationalization of precautionary statements, and further clarification of some of the criteria to avoid differences in their interpretation.--Publisher's description.
At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. The coverage describes the basic principles and methods of risk assessment within their legislative frameworks (EU, USA, Japan and Canada).
Medical Data Sharing, Harmonization and Analytics serves as the basis for understanding the rapidly evolving field of medical data harmonization combined with the latest cloud infrastructures for storing the harmonized (shared) data. Chapters cover the latest research and applications on data sharing and protection in the medical domain, cohort integration through the recent advancements in data harmonization, cloud computing for storing and securing the patient data, and data analytics for effectively processing the harmonized data. - Examines the unmet needs in chronic diseases as a part of medical data sharing - Discusses ethical, legal and privacy issues as part of data protection - Combines data harmonization and big data analytics strategies in shared medical data, along with relevant case studies in chronic diseases
This is a unique compilation on the use of leaching/extraction methods in different fields. The use of leaching test methods is increasing in various areas including: waste treatment and disposal; incineration of waste; soil clean-up and reuse of cleaned soil; sludge treatment. This has led to (and may increasingly lead to) the development of a large number of very similar tests in these different fields. However, these developments are taking place with no clear understanding of their mutual relationships. In view of these developments, efforts are needed to harmonize the leaching procedures that could be adapted for different matrices, as well as validate the use of existing tests in other fields. The development of a wide variety of leaching/extraction tests for different matrices is undesirable from a regulatory point of view and undesirable for industry. Clarity in testing is crucial in producer-consumer relations. This collective document will assist in improving the understanding of leaching from a variety of sources and will, where appropriate, help to bring together the approaches used in different technical fields and in different countries.
Taking into account toxicity levels at normal consumption levels, intake per kg bodyweight and other acknowledged considerations, each chapter in this book will be based on one or more proven examples. It is intended to provide specific examples and potential improvements to the safety of the world's food supply, while also increasing the amount of food available to those in undernourished countries. This book is designed to to provide science-based tools for improving legislation and regulation. - Reduce amount of food destroyed due to difference in regulations between nations - Positively impact the time-to-market of new food products by recognizing benefit of "one rule that applies to all" - Use the comparison of regulations and resulting consequences to make appropriate, fully-informed decisions - Employ proven science to obtain global consensus for regulations - Understand how to harmonize test protocols and analytical methods for accurate measurement and evaluation - Take advantage of using a risk/benefit based approach rather than risk/avoidance to maximize regulatory decisions
The first book of its kind, Handbook of Chemical Regulations: Benchmarking, Implementation, and Engineering Concepts introduces the concept of global harmonization and interlinks between regulations and examines the reasons behind major requirements for chemical manufacture, article production, and distribution, importation, and usage. A compendium