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"This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.
Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.
This fully updated Second Edition focuses sharply on clinical PET-CT and SPECT-CT examinations, omitting lengthy physics discussions. The book is now strictly disease oriented and integrates PET-CT and SPECT-CT applications completely. When both techniques are relevant for a disease, they are discussed together; when only one is relevant, it is discussed alone. More than 1,200 illustrations are included. A bound-in DVD contains over 80 cases to be viewed in three orthogonal planes and different CT windows organized as reference and self-assessment files. The cases provide excellent training and allow readers to test their abilities in making diagnoses on their own.
inch....this work is likely to become a standart work very quickly and is to be recommended to all schools where recorder studies are undertaken inch. (Oliver James,Contact Magazine) A novel and comprehensive approach to transferring from the C to F instrument. 430 music examples include folk and national songs (some in two parts), country dance tunes and excerpts from the standard treble repertoire ofBach, Barsanti, Corelli, Handel, Telemann, etc. An outstanding feature of the book has proved to be Brian Bonsor's brilliantly simple but highly effective practice circles and recognition squares designed to give, in only a few minutes, concentrated practice on the more usual leaps to and from each new note and instant recognition of random notes. Quickly emulating the outstanding success of the descant tutors, these books are very popular even with those who normally use tutors other than the Enjoy the Recorder series.
This volume is a unique overview of cardiovascular development from the cellular to the organ level across a broad range of species. The first section focuses on the molecular, cellular, and integrative mechanisms that determine cardiovascular development. The second section has eight chapters that summarize cardiovascular development in invertebrate and vertebrate systems. The third section discusses the effects of disease and environmental and morphogenetic influences on nonmammalian and mammalian cardiovascular development. It includes strategies for the management of congenital cardiovascular malformations in utero and postnatally.
Disasters such as earthquakes, cyclones, floods, heat waves, nuclear accidents, and large scale pollution incidents take lives and cause exceptionally large health problems. The majority of large-scale disasters affect the most vulnerable populations, which are often comprised of people of extreme ages, in remote living areas, with endemic poverty, and with low literacy. Health-related emergency disaster risk management (Health-EDRM) [1] refers to the systematic analysis and management of health risks surrounding emergencies and disasters; it plays an important role in reducing hazards and vulnerability along with extending preparedness, response, and recovery measures. This concept encompasses risk analyses and interventions, such as accessible early warning systems, timely deployment of relief workers, and the provision of suitable drugs and medical equipment, to decrease the impact of disaster on people before, during, and after disaster events. Disaster risk profiling and interventions can be at the personal/household, community, and system/political levels; they can be targeted at specific health risks including respiratory issues caused by indoor burning, re-emergence of infectious disease due to low vaccination coverage, and gastrointestinal problems resulting from unregulated waste management. Unfortunately, there has been a major gap in the scientific literature regarding Health-EDRM. The aim of this Special Issue of IJERPH was to present papers describing/reporting the latest disaster and health risk analyses, as well as interventions for health-related disaster risk management, in an effort to address this gap and facilitate major global policies and initiatives for disaster risk reduction.
Reviews recent experimental findings and current thinking on epithelial appendage morphogenesis. Contains sections on overview, morphogenesis of epithelial appendages on the body surface and within the body, molecular mechanisms, models, and approaches. Specific subjects include early molecular events in feather morphogenesis, evolutionarily conserved gene interactions, and molecular biology of anhidrotic ectodermal dysplasia. Many chapters contain summary diagrams of the formative process of organs, with cellular and molecular explanations. Annotation copyrighted by Book News, Inc., Portland, OR
Disasters such as earthquakes, cyclones, floods, heat waves, nuclear accidents, and large-scale pollution incidents take lives and incur major health problems. The majority of large-scale disasters affect the most vulnerable populations, which often comprise extreme ages, remote living areas, and endemic poverty, as well as people with low literacy. Health emergency and disaster risk management (Health-EDRM) refers to the systematic analysis and management of health risks surrounding emergencies and disasters, and plays an important role in reducing the hazards and vulnerability along with extending preparedness, responses, and recovery measures. This concept encompasses risk analyses and interventions, such as accessible early warning systems, the timely deployment of relief workers, and the provision of suitable drugs and medical equipment to decrease the impact of disasters on people before, during, and after an event (or events). Currently, there is a major gap in the scientific literature regarding Health-EDRM to facilitate major global policies and initiatives for disaster risk reduction worldwide.
Continuous professional development is of great importance if one is to develop quality professional work. This book contains some of the latest research advances related to the field of Physical Education and Sports. In today's globalized world, continuous and permanent education is necessary and essential to complement the initial training and previous experience. In this book, you can find a wide range of works focused on innovative teaching methodologies and psychological variables to take into account to improve classes and training. These studies on the most forward-looking technological advances in physical activity and sports are useful for those who seek to be up-to-date on this type of research. In addition, these studies will be useful to consult regarding current lifestyle, the creation of healthy habits, the promotion of physical activity in one’s free time, and the importance of leading an active life.