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Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences. This volume, The Cerebellum and Memory Formation: Structure, Computation and Function, covers topics including feedback control of cerebellar learning; cortico-cerebellar organization and skill acquisition; cerebellar plasticity and learning in the oculomotor system, and more. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research The volume reflects current thinking about the ways in which the cerebellum can engage in learning, and the contributors come from a variety of research fields The chapters express perspectives from different levels of analysis that range from molecular and cellular mechanisms through to long-range systems that allow the cerebellum to communicate with other brain areas
The Cerebellum provides a concise, accessible overview of modern data on physiology and function of the cerebellum as it relates to learning, plasticity, and neurodegenerative diseases. Encompassing anatomy and physiology, theoretical work, cellular mechanisms, clinical research, and disorders, the book covers learning and plasticity while introducing the anatomy of the cerebellum. Known and proposed "functions of the cerebellum" are addressed on clinical, physiological, cellular, and computational levels, providing academics, researchers, medical students, and graduate students with an invaluable reference.
This volume of International Review of Neurobiology is on Cerebellar Conditioning and Learning. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field.
In this book, laboratory leaders on cerebellar neuroscience have revised the present body of knowledge about cerebellum anatomy and function. The trip throughout the cerebellar vineyard organization starts from the causal study of morphogenesis (that is, the molecular and cellular mechanisms underplaying form generation) to the molecular mechanism regulation cellular differentiation: Basson, Dusart, Hawkes, Martinez and Rosi’s groups contributions. Then, neurodevelopmental anomalies associated with structural disorganization are revised in Jissendi and Batkovich’s group reviews, describing and discussing pathogenic processes. Finally, functional mechanisms of cerebellar circuits involved in motor learning are revised by Delgado-Garcia and Armengol’s group contribution.
This book is concerned with the involvement of the cerebellum in learning and remembering motor tasks. It is unique in discussing plasticity at both the cellular and at the behavioral level.
Leading neuroscientist Dr. Masao Ito advances a detailed and fascinating view of what the cerebellum contributes to brain function. The cerebellum has been seen as primarily involved in coordination of body movement control, facilitating the learning of motor skills such as those involved in walking, riding a bicycle, or playing a piano. The cerebellum is now viewed as an assembly of numerous neuronal machine modules, each of which provides an implicit learning capability to various types of motor control. The cerebellum enables us to unconsciously learn motor skills through practice by forming internal models simulating control system properties of the body parts. Based on these remarkable advances in our understanding of motor control mechanisms of the cerebellum, Ito presents a still larger view of the cerebellum as serving a higher level of brain functions beyond movements, including the implicit part of the thought and cognitive processes that manipulate knowledge. Ito extends his investigation of the cerebellum to discuss neural processes that may be involved implicitly in such complex mental actions as having an intuition, imagination, hallucination, or delusion.
The cerebellum is an intriguing component of the brain. In humans it occupies only 10% of the brain volume, yet has approximately 69 billion neurons; that is 80% of the nerve cells in the brain. The cerebellum first arose in jawed vertebrates such as sharks, and early vertebrates also have an additional cerebellum-like structure in the hindbrain. Shark cerebellum-like structures function as adaptive filters to discriminate 'self' from 'other' in sensory inputs. It is likely that the true cerebellum evolved from these cerebellum-like precursors, and that their adaptive filter functionality was adopted for motor control; paving the way for the athleticism and movement finesse that we see in swimming, running, climbing and flying vertebrates. This book uses an evolutionary perspective to open up the exciting body of work that is cerebellar research to a wide audience. Understanding the brain is of interest to many people, from many different backgrounds, and for many different reasons. Therefore, understanding cerebellum is a significant step towards the wider challenge of understanding the brain. This book will be of interest to neuroscientists, neurologists and psychologists, in addition to computer scientists, and engineers concerned with machine/human interactions and robotics.
Based on the 75th Fujihara Seminar held in December 2018 in Tokyo, Japan, this volume explores the latest research on the cerebellum. Contributors seek to examine the cerebellum's role as a unique hub for brain activity and discover new information about its purpose. The discussion is broad, ranging from evolutionary topics to therapeutic strategy and addresses both physiology and pathology. Subjects covered include anatomy, information processing, complex spikes, plasticity, modeling, and spinocerebellar ataxias. The volume is intended to set the stage for the future of cerebellar research and guide both basic and clinical researchers.
The Neuronal Codes of the Cerebellum provides the most updated information on what is known on the topics of the cerebellum’s anatomy and single cell physiology, two areas where there has been a gap in knowledge regarding the specific codes it uses to process information internally and convey commands to other brain regions. This has created difficulties for researchers and clinicians looking to develop an understanding of the mechanisms by which it contributes to behavior and how its dysfunction causes neurological symptoms. Focused on findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes, this edited volume will aid scientists in overcoming that knowledge gap, also serving as the first resource to broadly address the different aspects of spike coding in the cerebellum that focuses on spike train analysis. Compiles current knowledge about functioning of the cerebellum on a cellular basis and how information is encoded in the cerebellum Highlights findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes Contents include an introduction to the cerebellum and experimental/theoretical techniques, as well as the function of cerebral coding during disorder, learning, behavior generation, motor behavior, and more Bridges the gap for cerebellar researchers between single cell biophysics/anatomic studies and behavioral studies Incorporates various in vivo approaches with different behavioral paradigms in primates and rodents, modeling studies of coding, and in vitro approaches