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A conspicuous portion of the peripheral nervous system is part of the 'vegetative nervous system'; it includes all the neurons which innerv ate the viscera, salivary and lacrimal glands, the heart and blood vessels, all other smooth muscles of the body, notably the intrinsic muscles of the eye and the muscles of the hair. Only part of the system belongs to the peripheral nervous system: it has also its own nuclei and pathways in the central nervous system. The distinction between visceral and somatic functions is a very old one in our culture. With the development of neurology the notion of a widespread nervous control of body functions emerged. Winslow (1732) used the term nervi sympathici majores for those nerves, which he thought to carry about 'sympathies' and then co ordinate various viscera's functions. His was an anatomical break through, which obscured Willis' 'intercostal nerve' and Vesalius 'cranial nerve'. The notion was developed among others by John stone (1764) who arrived, with the aid of some very accurate anatomical observations, at the problem of the nervous influence on motion and sensitivity of viscera. By the end of the eighteenth century, it was clear, with Bichat (1800), that what he called 'sympa thetic nervous system' (and his pupil Reil, a few years later, 'vegeta tive nervous system ') controlled visceral functions (fa vie organique), whereas somatic functions (fa vie animafe) were under direct control from the brain and spinal cord.
This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.
Central autonomic circuits in the brain and spinal cord are essential to vertebrate life because they are involved in controlling all basic bodily functions, including blood pressure, feeding, body temperature regulation voiding and reproduction. This wide-ranging text emphasizes the extraordinary advances that have been made over the last 20 years in understanding how the central nervous system controls autonomic functions.
Aging of the Autonomic Nervous System is the first book devoted to the aging of the autonomic nervous system. The book presents the most recent findings on topics such as general aspects of the autonomic nervous system, main neurotransmitter systems, age-dependent changes of neuroeffector mechanisms in target organs, and therapeutic perspectives. It also provides a comprehensive analysis of the possible consequences of these findings. Aging of the Autonomic Nervous System will be a useful volume for gerontologists and neuroscientists.
The Studies in Physiology series provides a concise introduction to developments in complex areas of physiology for a wide audience. Published on behalf of the Physiology Society, Cardiovascular Regulation provides an up-to-date account of our current understanding of the control of the cardiovascular system that is not covered by existing textbooks. Both students and lecturers of cardiovascular and exercise physiology, medicine, dentistry and biomedical sciences will find this book informative and easy to read. Each chapter has numerous summary boxes. 'Essential reading' suggestions provide additional reading for undergraduates and the suggestions for 'Further reading' cover the subject to postgraduate level.
In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.