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Cells are the smallest units capable of sustaining life, and they make up virtually every aspect of the human body. From the strands of hair at the top of the head to the nails on fingers and toes, every structure of the human body is composed of cells. Groups of cells form tissues and organs, which allow the body to function as an organized system. Skin, the body's largest organ, forms a waterproof barrier that provides protection against invading microorganisms and acts as a sensory and thermoregulatory structure. Cells, Tissues, and Skin, Third Edition explores the properties of each of these components in our bodies. Packed with full-color photographs and illustrations, this absorbing book provides students with sufficient background information through references, websites, and a bibliography.
Skin, cells, and tissues provide the foundations of the human body--from the first line of defense against disease to the basic components of complex organs and systems.
The Structure and Function of Skin, Third Edition is devoted to all matters pertaining to the structure and function of the skin. Drawing upon the accumulated data derived from embryology, histology, anatomy, physiology, biochemistry, and pharmacology, this book presents an overview of skin, with emphasis on human skin. Topics range from the biological functions of the dermis to the histochemical and microchemical properties of the epidermis; the effects of protein deficiency on hair growth; cutaneous innervation; nail regeneration and growth; sebaceous glands; and eccrine sweat glands. This book is organized into 12 chapters and begins with an overview of the structure and function of skin, and then discusses the epidermis and its structural features. Special consideration is given to the life cycle of epidermal cells; the properties and function of stratum corneum; and other cells in the epidermis including melanocytes, the cells of Langerhans, and Merkel cells. The chapters that follow focus on age-related changes in the dermis, cutaneous blood flow, changes in skin circulation, and the dermal nerve network. The book also considers hair growth and differentiation; the effects of malnutrition on the morphology of hair roots; and the structure and development of the nails. A chapter describing the cytochemistry and pharmacology of eccrine sweat glands concludes the book. This book is written primarily for dermatologists, whether seasoned veterans or neophytes, and will also be useful to all biologists who are interested in biomedical disciplines.
Cells are the smallest units capable of sustaining life, and they make up virtually every aspect of the human body. From the strands of hair at the top of the head to the nails on fingers and toes, every structure of the human body is composed of cells. Groups of cells form tissues and organs, which allow the body to function as an organized system. Skin, the body’s largest organ, forms a waterproof barrier that provides protection against invading microorganisms and acts as a sensory and thermoregulatory structure. Cells, Tissues, and Skin, Third Edition explores the properties of each of these components in our bodies. Packed with full-color photographs and illustrations, this absorbing book provides students with sufficient background information through references, websites, and a bibliography.
The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs
A comprehensive resource on skin and skin disorders with current information on diseases of the skin and related topics with available treatments, and resources available.