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The new electronic edition of Mitelman's Catalog of Chromosome Aberrations in Cancer continues its legacy as the most complete, up-to-date sourcebook available on the chromosomal changes that have been reported in cases of human neoplastic disorder. Replacing the print version, this CD-ROM is an interactive database which combines all of the information found in the print edition, along with new databases which are currently not included in print. In addition, this electronic version offers all the advantages of searchability and hyperlinked cross references which are unique to this format.
First multi-year cumulation covers six years: 1965-70.
A systematic, concise and uniform presentation of the chromosome changes reported in human neoplastic disorders. Due to the dramatic increase of data, especially on solid tumors which typically have very complex karyotypes, the number of entries has almost doubled in the present edition. This version contains several improvements: all karyotypes have been adjusted according to the ISCN (1991) nomenclature recommendations, extremely complex karyotypes are now displayed unabridged, clonal aberrations are classified by conventional criteria as nonneoplastic disorders/lesions and morphological diagnoses (particularly those of solid tumors) have been reorganized and extended to make retrieval of data on specific tumor types more accessible.
This edited book, Chromosomal Abnormalities - A Hallmark Manifestation of Genomic Instability, contains a series of chapters highlighting several aspects related to the generation of chromosomal abnormalities in genetic material. We are extremely grateful to the authors who had contributed with valuable information about the role of genomic instability in pathological disorders as well as in the evolution process.