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This updated and revised edition delineates the basic concepts and fundamental principles needed to grasp current issues in modern toxicology. In addition, new contributions help to redefine the book's scope and coverage, and illuminate new and emerging areas of toxicologic interest.
This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.
The third edition of the Toxicologist’s Pocket Handbook, like the first two editions, is a scaled-down version of the best-selling Handbook of Toxicology. It provides the most frequently used toxicology reference information in a convenient pocket-sized book. The format remains the same as the earlier editions to allow basic reference information to be located quickly, with the information placed in sections specific to subspecialties of toxicology. A detailed table of contents lists all tables and figures contained in the book by section. This expanded edition contains a number of tables not found in the second edition added to sections on lab animals, general toxicology, dermal and ocular toxicology, genetic toxicology/carcinogenesis, neurotoxicology, immunotoxicology, reproductive/developmental toxicology, industrial chemical, and pharmaceutical toxicology. New information is presented for additional laboratory animals such as swine and primates, infusion recommendations, newer methods such as the local lymph node assay, and reference safety pharmacology values for standard species. Additional information on typical genetic toxicology and immunotoxicology assays as well as in vitro assays for eye irritation are provided. Some tables from the second edition have been updated to include new information that has arisen since the earlier edition went to press. Information from the second edition, such as regulatory requirements that are no longer applicable, has been deleted.
Are you studying for the toxicology Boards? Are you a toxicologist who would like to have a source of recent questions for review? Are you enrolled in a general toxicology course at the advanced undergraduate or graduate level? 2000 Toxicology Board Review Questions provides a means to evaluate your knowledge and understanding of the significant newer concepts in the area of general toxicology. The questions in the book are based on information contained in some of the most well-respected and recent textbooks. The book is divided into 35 specialty chapters, and all answers are referenced to the original textbook source.The book will be useful to toxicologists, clinical pharmacologists, emergency room physicians, clinical pharmacists, and forensic pathologists.
Accompanying DVD-ROM in pocket at the rear of book.
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition: