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The thesis by Mercè Pacios exploits properties of carbon nanotubes to design novel nanodevices. The prominent electrochemical properties of carbon nanotubes are used to design diverse electrode configurations. In combination with the chemical properties and (bio)functionalization versatility, these materials prove to be very appropriate for the development of electrochemical biosensors. Furthermore, this work also evaluates the semiconductor character of carbon nanotubes (CNT) for sensor technology by using a field effect transistor configuration (FET). The CNT-FET device has been optimized for operating in liquid environments. These electrochemical and electronic CNT devices are highly promising for biomolecule sensing and for the monitoring of biological processes, which can in the future lead to applications for rapid and simple diagnostics in fields such as biotechnology, clinical and environmental research.
Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.
Carbon Nanotubes and Graphene is a timely second edition of the original Science and Technology of Carbon Nanotubes. Updated to include expanded coverage of the preparation, purification, structural characterization, and common application areas of single- and multi-walled CNT structures, this work compares, contrasts, and, where appropriate, unitizes CNT to graphene. This much expanded second edition reference supports knowledge discovery, production of impactful carbon research, encourages transition between research fields, and aids the formation of emergent applications. New chapters encompass recent developments in the theoretical treatments of electronic and vibrational structures, and magnetic, optical, and electrical solid-state properties, providing a vital base to research. Current and potential applications of both materials, including the prospect for large-scale synthesis of graphene, biological structures, and flexible electronics, are also critically discussed. Updated discussion of properties, structure, and morphology of biological and flexible electronic applications aids fundamental knowledge discovery Innovative parallel focus on nanotubes and graphene enables you to learn from the successes and failures of, respectively, mature and emergent partner research disciplines High-quality figures and tables on physical and mathematical applications expertly summarize key information – essential if you need quick, critically relevant data
This book presents tools and techniques for the development of miniature biosensors and their applications. The initial chapters discuss the advancements in the development of the transduction techniques, including optical, electrochemical, and piezoelectric, which are used for miniaturized biosensors. The book also reviews several technologies, such as nanotechnology, nanobiotechnology, immune-technology, DNA-technology, micro-manufacturing technology, electronic-circuit technology to increase the miniaturization and sensitivity of the biosensor platform. Subsequently, the chapters illustrate the applications of miniaturized biosensing systems in point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics, and biomedical research. Towards the end, the book discusses the advanced applications of biosensors in water quality monitoring, especially on-line detection systems and on-site detection of pesticides, heavy metals and bacteria in water. This book is an invaluable source for scientists working in biochemical engineering, bioengineering, and biomedical engineering in academia and industry.
Carbon nanotubes are exceptionally photostable fluorophores that emit in the near infrared range. Their novel optical properties make them particularly appealing for applications in biosensing. This chapter focuses on the state-of-the-art development of optical biosensors based on single-walled carbon nanotubes (SWCNTs); also, it draws attention to the basic photophysics of SWCNTs, optical-sensing mechanisms, and surface functionalization principles. The concerted efforts from the research community in the past decade have enabled the realization of several SWCNT-based optical biosensors that provide real-time, non-invasive analyte detection. We review the performance of these biosensors with regard to their sensitivity, selectivity and response time, and highlight the prospects and challenges of constructing biosensors for more advanced sensing applications.
This new book discusses a selection of advanced topics on carbon nanotubes—their extraordinary properties, structure, design, fabrication, development, engineering, functionalization, carbon nanotube enabled nanocomposites, characterization, and, moreover, their utility in many applications. The volume highlights the amazing potential of advanced CNT composites in automotive, aeronautics, spacecrafts, transistors replacing Si electronics, energy, purification, hydrogen storage, tissue regeneration, electrochemical supercapacitors, sensing, biomedical applications, agriculture, energy, and technical applications. The book specifically discusses the applications of carbon nanotubes for a greener environment, as well as applications for biomedical uses, in drug delivery, and in display technology. It also explores the uses of CNTs in the energy and aerospace industries, such as for solar energy conversion, as a lubricant additive for enhancing energy efficiency, and more. Other chapters explore the potential of carbon nanotubes in hydrogen storage and carbon nanotube electronics.
Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy
Carbon Nanotube-Based Sensors: Fabrication, Characterization, and Implementation highlights the latest research and developments on carbon nanotubes (CNTs) and their applications in sensors and sensing systems. It offers an overview of CNTs, including their synthesis, functionalization, characterization, and toxicology. It then delves into the fabrication and various applications of CNT-based sensors. FEATURES Defines the significance of different forms of CNT-based sensors synthesized for diverse engineering applications and compares the feasibility of their generation Helps readers evaluate different types of fabrication techniques to generate CNTs and their subsequent sensing Discusses fabrication of low-cost, efficient CNTs-based sensors that can be used for diverse applications and sheds light on synthesis methods for a range of printing techniques Highlights challenges and advances in security-related issues using CNTs-based sensors This book is aimed at researchers in the fields of materials and electrical engineering who are interested in the development of sensor technology for industrial, biomedical, and related applications.
Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors. Filling a gap in the literature, it showcases the multidisciplinary, innovative developments in this highly important area and provides pointers towards commercialisation. Delivering a single, comprehensive work, it appeals to graduate students and professional researchers across academia and industry.