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Estimating M and O from P; The first threshold; Regulation of the major gene; The evolution of dominance; Canalisation and selection for an intermediate; Canalisation and selection against variability; Genetic correlations.
Darwin's theory of evolution by natural selection was based on the observation that there is variation between individuals within the same species. This fundamental observation is a central concept in evolutionary biology. However, variation is only rarely treated directly. It has remained peripheral to the study of mechanisms of evolutionary change. The explosion of knowledge in genetics, developmental biology, and the ongoing synthesis of evolutionary and developmental biology has made it possible for us to study the factors that limit, enhance, or structure variation at the level of an animals' physical appearance and behavior. Knowledge of the significance of variability is crucial to this emerging synthesis. Variation situates the role of variability within this broad framework, bringing variation back to the center of the evolutionary stage. - Provides an overview of current thinking on variation in evolutionary biology, functional morphology, and evolutionary developmental biology - Written by a team of leading scholars specializing on the study of variation - Reviews of statistical analysis of variation by leading authorities - Key chapters focus on the role of the study of phenotypic variation for evolutionary, developmental, and post-genomic biology
This book provides an analysis of the nature vs. nuture debate, arguing for an end to the 'either/or' nature of the discussions in favor of a recognition that environmental and genetic factors interact throughout life to form human traits.
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.
Over the past 20 years, the role of phenotypic plasticity in Darwinian evolution has become a hotly debated topic among biologists and philosophers of science. For instance, in the Extended Evolutionary Synthesis, a new form of evolutionary theory that aims to include processes not taken into account by standard theory (the Modern Synthesis), the question of the remarkable plasticity of living beings is central. Beyond Lamarckism: Plasticity in Darwinian Evolution, 1890–1970 shows that the evolutionary impact of plasticity was in fact debated long before the emergence of the current debate on the limits of the Modern Synthesis. The question of how the plasticity of organisms could play a causal role in Darwinian evolution was raised on two separate occasions: first, around 1900, with the emergence of the theory of “organic selection” and, second, during the formation of the Modern Synthesis itself, in the mid-20th century. Out of these reflections came a very large number of concepts, models, and many different terms (“organic selection”, “stabilizing selection”, “genetic assimilation”, “Baldwin effect”, etc.), which were often developed independently in various research traditions and empirical contexts. This book also looks at the reasons why these conceptions have been downplayed in the standard understanding of adaptive evolution. Showing the extraordinary complexity of this history, Beyond Lamarckism is aimed at readers interested in evolutionary theory, whether philosophers, biologists, or historians.
Volume 12 is devoted to current and future approaches to insect management and control. The topics discussed cover chemical control, including the use of juvenile hormone analogs, microbiological methods, including viral and fungal agents, biological control, and genetic approaches to insect control. The 20 chapters, all amply referenced and illustrated, well demonstrate the multidisciplinary nature of the subject and the degree of international effort that has led to the present state of knowledge. Fifteen of the chapters are devoted to the action of insecticides, reflecting the immensity of the subject. The past 30 years have witnessed remarkable advances in the scientific basis of insect control and this volume provides a convenient point of entry into the massive amount of literature now available.
This is the third, penultimate volume in the Toward a Theoretical Biology series. The contributors agree that there is a major problem in finding methods of dealing with the great complexity of biological systems. Molecular biology has given us considerable insight into the nature of the elementary units and processes of life, but to understand how these are put together to form systems that are usually too complicated to be analysed completely, but exhibit global properties of simplicity, presents biologists with an intellectual challenge that physical sciences and chemistry must also face. The problem is approached from several different angles: quantum physics, topology, and statistical mechanics. A stimulating discussion is recorded: that the behaviour of randomly constructed networks exhibits simplicity. Thoughtful analyses of complexities in such basic biological processes as the genetic control of differentiation, evolution, and ecology is also included. Some of the questions dealt with are: What kinds of theories should we wish to have in connection with developmental biology? And have we got them? The subject matter of 'Organization Stability and Process' is defined as the basic concept of biology. None of the contributors herein contained is a molecular biologist in the modern sense, but molecular biology casts a shadow over this work, at least in so far as they challenge its interpretative aggressiveness and its enthusiastic but unendearing self-confidence and self-sufficiency. This volume inaugurates a new and authentic style of scientific literature. The contributions are thoughtful, imaginative, illuminating, and exceptionally well written.
Quantitative Genetic Variation describes some of the experimental approaches to quantitative genetic variation, along with their potential applications and limitations. It considers one of the most widely applicable tools, i.e., biometrical analysis, as well as individual polygenic effects, specific components of a quantitative genetic trait, and artificial selection, and it shows how selection experiments can address specific developmental and genetic questions. Organized into four sections encompassing 17 chapters, this volume begins with a historical overview of the study of quantitative genetic variation, along with genetic variation in fungi and Drosophila. It then discusses the biometrical approach to quantitative variation, selection theory and analysis, uses and limitations of polygene mapping, and computer simulation of the breeding program for polygene location. The reader is also introduced to genes affecting quantitative aspects of physiology in rodents, as well as cytological markers and quantitative variation in wheat. This book will be extremely useful to students, researchers, and geneticists.
In his extraordinary book, Mayr fully explored, synthesized, and evaluated man's knowledge about the nature of animal species and the part they play in the process of evolution. Now, in this long-awaited abridged edition, Mayr's definitive work is made available to the interested nonspecialist, the college student, and the general reader.