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The last two decades have seen prodigious growth in the application of brain imaging methods to questions of substance abuse and addiction. Despite considerable advances in our understanding of the central effects of drugs provided by preclinical data, relatively little direct evidence was known of how substances of abuse affect the brain and other eNS processes in humans. Brain imaging techniques have allowed access to the human brain and enabled the asking of questions never before imagined. The positron emission tomography (PET) data ofVolkow and her colleagues in the late 1980s, showing the uptake and time course of cocaine's binding in the human brain, revealed for the first time the distinct sites of action of this drug. This work was extremely important because it showed clearly, through imaging a drug in the brain of a living human, that the time course of its action paralleled the behavioral state of "high. " This study marked a turning point in our understanding of drug-brain-behav ior interactions in humans. Many more investigations of drug effects on the structure and function of the human brain were soon to follow, leading to much better insights into brain systems. Brain imaging allowed for the direct assessment of structural and functional anatomy, biology, and chemistry in substance abusers.
Explores how the explosion of neuroscience-based evidence in recent years has led to a fundamental change in how forensic psychology can inform working with criminal populations. This book communicates knowledge and research findings in the neurobiological field to those who work with offenders and those who design policy for offender rehabilitation and criminal justice systems, so that practice and policy can be neurobiologically informed, and research can be enhanced. Starting with an introduction to the subject of neuroscience and forensic settings, The Wiley Blackwell Handbook of Forensic Neuroscience then offers in-depth and enlightening coverage of the neurobiology of sex and sexual attraction, aggressive behavior, and emotion regulation; the neurobiological bases to risk factors for offending such as genetics, developmental, alcohol and drugs, and mental disorders; and the neurobiology of offending, including psychopathy, antisocial personality disorders, and violent and sexual offending. The book also covers rehabilitation techniques such as brain scanning, brain-based therapy for adolescents, and compassion-focused therapy. The book itself: Covers a wide array of neuroscience research Chapters by renowned neuroscientists and criminal justice experts Topics covered include the neurobiology of aggressive behavior, the neuroscience of deception, genetic contributions to psychopathy, and neuroimaging-guided treatment Offers conclusions for practitioners and future directions for the field. The Handbook of Forensic Neuroscience is a welcome book for all researchers, practitioners, and postgraduate students involved with forensic psychology, neuroscience, law, and criminology.
This book offers a comprehensive overview of the forensic and radiological aspects of pathological findings, focusing on the most relevant medico-legal issues, such as virtual autopsy (virtopsy), anthropometric identification, post-mortem decomposition features and the latest radiological applications used in forensic investigations. Forensic medicine and radiology are becoming increasingly relevant in the international medical and legal field as they offer essential techniques for determining cause of death and for anthropometric identification. This is highly topical in light of public safety and economic concerns arising as a result of mass migration and international tensions. The book discusses the latest technologies applied in the forensic field, in particular computed tomography and magnetic resonance, which are continuously being updated. Radiological techniques are fundamental in rapidly providing a full description of the damage inflicted to add to witness and medical testimonies, and forensic/radiological anthropology supplies valuable evidence in cases of violence and abuse. Written by international experts, it is of interest to students and residents in forensic medicine and radiology. It also presents a new approach to forensic investigation for lawyers and police special corps as well as law enforcement agencies.
One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
The Metropolitan Police Service (MPS), now in its 175th year, has a long tradition of working with doctors. In fact, the origin of the forensic p- sician (police surgeon) as we know him or her today, dates from the passing by Parliament of The Metropolitan Act, which received Royal Assent in June of 1829. Since then, there are records of doctors being “appointed” to the police to provide medical care to detainees and examine police officers while on duty. The MPS has been involved in the training of doctors for more than 20 years, and has been at the forefront of setting the highest standards of wo- ing practices in the area of clinical forensic medicine. Only through an awa- ness of the complex issues regarding the medical care of detainees in custody and the management of complainants of assault can justice be achieved. The MPS, therefore, has worked in partnership with the medical profession to ensure that this can be achieved. The field of clinical forensic medicine has developed in recent years into a specialty in its own right. The importance of properly trained doctors working with the police in this area cannot be overemphasized. It is essential for the protection of detainees in police custody and for the benefit of the criminal justice system as a whole. A book that assists doctors in the field is to be applauded.
Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.
This volume examines how new cutting edge forensic techniques are currently being applied or have the potential to be applied in judicial proceedings. Examples include new applications of Raman spectroscopy, quantum chemistry, lithium in DNA analysis, and the burgeoning area of toxicogenetics. In each case legal issues are addressed, including the