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Methyl methacrylate (MMA) is the basic component of bone cements. To use it, a dough is prepared from the liquid and powder by mixing right before application, which is normally done by the operating team. During its working phase the dough is then inserted into the tissue where polymerization is completed. Thus, the final implant polymethyl methacrylate (PMMA) is only created at the implantation site. Besides methyl methacrylate, bone cements sometimes contain other methacrylates, such as butyl methacrylate. To achieve X-ray opacity, radiopacifiers (zirconium dioxide or barium sulfate) are added to the powder. Both the liquid and powder components contain additives (initiator and activator) that launch polymerization and control the set ting when mixed together. Moreover, softener and emulsifiers are some times used. The addition of antibiotics to the powder component in order to prevent or treat infections has become especially important. Commercial bone cements differ in composition and the course of curing. Some are designed for high and others for low viscosity. The way the user handles and applies the cement always crucially influences the quality of the implant. This is why clear and comprehensive information about the cements should be available to show the user how all the relevant factors work It should also be possible together and how they depend on each other.
With an increasing number of bone cements available, it is vital that the correct material is selected for specific clinical procedures. A review of the most recent research in this field, this book covers such topics as hip replacements, verteboplasty and wear particles and osteolysis. It reviews materials and types of cement such as acrylic, polymethylmethacrylate and calcium phosphate cements and address the mechanical properties of bone cements such as fracture toughness and dynamic creep. The book closes with an examination of methods to enhance the properties of bone cements such as antibiotic loaded bone cements and bioactive cements.
Bone cements are widely used in orthopaedic applications to anchor implants to existing bone, reconstruct bone and deliver bioactive agents to the body. With an increasing number of bone cements available, it is vital that the correct material is selected for specific clinical procedures. Orthopaedic bone cements reviews the most recent research in this field.Part one discusses the current uses of orthopaedic bone cements with chapters on such topics as hip replacements, verteboplasty and wear particles and osteolysis. Part two reviews materials and types of cement such as acrylic, polymethylmethacrylate and calcium phosphate cements. Chapters in Part three address the mechanical properties of bone cements such as fracture toughness and dynamic creep. The final section examines methods to enhance the properties of bone cements with coverage of themes such as antibiotic loaded bone cements and bioactive cements.With its eminent editor and multidisciplinary team of international contributors, Orthopaedic bone cements is an invaluable reference for materials scientists, medical researchers and all those involved in the development of bone cements for orthopaedic applications and joint replacement. - Provides a review of recent research focussing on improving the mechanical and biological performance of bone cements - Discusses the current applications of bone cements particularly in hip replacement, verteboplasty and wear particles - Reviews types of materials and acrylic, polymethlymethacrylate and calcium phosphate as types of cements
Cemented Total Hip Arthroplasty (THA) remains one of the most successful procedures in Orthopaedic surgery. It has become very clear that it is the surgical expertise, in particular the quality of the cementing technique, which will affect long-term outcome and success. It is the intention of this book to provide an up-to-date comprehensive assessment of the entire field of cemented THA. Special emphasis has been given to practice-relevant aspects: well-illustrated and detailed operative steps as a practical guideline, a basic science chapter and long-term outcome data are provided. Minimally invasive surgery, modern perioperative management and patient fast tracking are covered. A number of highly respected experts have contributed to this in-depth compilation of the "state of the art" in 2005. This book is written and intended for both, trainees and established arthroplasty surgeons who are dedicated to perform a well-cemented THA.
G. H. I. M. WALENKAMP, D. W. MURRAY Since the first use of bone cement, there has been much discussion about this important tool in arthroplasty. Many authors consider the cemented prosthesis as the gold standard when evaluating the outcome of primary prostheses. In a large number of total hip arthroplasties, as registered in the Scandi navian Hip Registers, important differences in revision risks have been docu mented between hospitals. These differences are partly due to the use of di verse cement techniques. In the analysis of data, the influence of these tech niques, as well as the different cement types, is clear. A recent disaster with a newly developed cement also illustrated that the quality of the cement must be assured, and that the introduction of a new material must be carefully prepared and followed-up. The new Palamed cement has been developed by the makers of the well known Palacos and Refobacin Palacos, which appeared to be the best ce ments in the Swedish register. An improvement was noted in slightly better handling characteristics, but the end product is the same as Palacos. As men tioned, this cement will be carefully followed-up in the near future. However, its introduction is a good reason to gather the expertise of some of the lead ing figures in the field in this book. II History of Bone Cements CHAPTER 2. 1 Industrial Development of Bone Cement Twenty-Five Years of Experience w. EGE, K. D.
This book provides an overview of the composition of polymeric and ceramic bone cements. It also discusses complex, biomimetic structures based on biomaterials, such as cells and bioactive molecules, which more closely resemble natural bone The first chapter describes the main concepts of the cementation process and the parameters affecting it, while the second chapter focuses on the composition and structure of candidate biomaterials. Lastly, the third and fourth chapters present recent research aimed at improving the ability of naked biomaterials to enhance bone healing by adding cells and bioactive agents.
New technologies, developments in implant design and advances in surgical technique have improved outcomes after joint replacement and decreased rate of complications. It is not a surprise that the number of arthroplasties increases steadily every year and nowadays more than one million patients undergo the procedure annually worldwide. This book is a sequel of a successful series dedicated to one of the fastest growing fields in orthopedics - arthroplasty. Aiming at dissemination of scientific research this book provides a profound overview of the recent evolution of technology and surgical techniques. New developments of implant design and current treatment strategies have been critically discussed by the contributing authors. The process of improving care for patients and standards of treatment requires straightforward access to up-to-date research and knowledge. The format of the publication allows easy and quick reference to shared ideas and concepts. We hope, that the current book will add significant contribution to the success of this endeavor.
Cement-based materials have been used by humans nearly since the dawn of civilization. The Egyptians used lime and gypsum cement to bind their aggregate materials, mud and straw, resulting in bricks that are used for building their famous Egyptian pyramids (between 3000 and 2500 BC). Hydrated cement is a cement material bonded together with water and used for building construction; it is characterized by acceptable chemical, physical, thermal, mechanical, and structural stability. It plays a main role in the creation of vessels for storage, roads to travel on, weather-resistant structure for protection, inert hard stabilizer for hazardous wastes, and so on. Due to the composition of these materials and their advantages, it has been practiced in different applications. Cement is an essential component of making concrete, the single most prevalent building material used worldwide for construction, skyscrapers, highways, tunnels, bridges, hydraulic dams, and railway ties. Besides their numerous desired properties, there are some undesirable features. To overcome these disadvantages, several studies were established to prepare, improve, and evaluate innovative cement-based materials. Despite its oldness and deep research, every year several methods and materials evolve and so do cement technology. This book intends to provide a comprehensive overview on recent advances in the evaluation of these materials.
Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. - Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area - Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing - Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges - Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites
The third edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons.This edition covers a range of updated and new content, ranging from chapters on materials analysis and selection, to methodologies and techniques used for joint replacement and clinical challenges of replacing specific joints. Key topics include tribological considerations and experiments; challenges in joint bearing surfaces; cementless fixation techniques; healing responses to implants. Clinical challenges and perspectives are covered with the aid of case studies.Thanks to its widespread collaboration and international contributors, Joint Replacement Technology, Third Edition is useful for materials scientists and engineers in both academia and the biomedical industry. Chemists, clinicians, and other researchers in this area will also find this text invaluable. - This third edition provides an updated comprehensive review of recent developments in joint replacement technology - Reviews a range of specific joints, biological and mechanical issues and fixation techniques - Includes revised and new content, such as sections on regulatory affairs, AI techniques and 3D printing