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This volume of the Biostatistics and Health Sciences Set focuses on statistics applied to clinical research.The use of SAS for data management and statistical modeling is illustrated using various examples. Many aspects of data processing and statistical analysis of cross-sectional and experimental medical data are covered, including regression models commonly found in medical statistics. This practical book is primarily intended for health researchers with a basic knowledge of statistical methodology. Assuming basic concepts, the authors focus on the practice of biostatistical methods essential to clinical research, epidemiology and analysis of biomedical data (including comparison of two groups, analysis of categorical data, ANOVA, linear and logistic regression, and survival analysis). The use of examples from clinical trials and epidemiological studies provide the basis for a series of practical exercises, which provide instruction and familiarize the reader with essential SAS commands. - Presents the use of SAS software in the statistical approach for the management of data modeling - Includes elements of the language and descriptive statistics - Supplies measures of association, comparison of means, and proportions for two or more samples - Explores linear and logistic regression - Provides survival data analysis
Learn how to solve basic statistical problems with Ron Cody's easy-to-follow style using the point-and-click SAS Studio tasks. Aimed specifically at the health sciences, Biostatistics by Example Using SAS Studio, provides an introduction to SAS Studio tasks. The book includes many biological and health-related problem sets and is fully compatible with SAS University Edition. After reading this book you will be able to understand temporary and permanent SAS data sets, and you will learn how to create them from various data sources. You will also be able to use SAS Studio statistics tasks to generate descriptive statistics for continuous and categorical data. The inferential statistics portion of the book covers the following topics: paired and unpaired t tests one-way analysis of variance N-way ANOVA correlation simple and multiple regression logistic regression categorical data analysis power and sample size calculations Besides describing each of these statistical tests, the book also discusses the assumptions that need to be met before running and interpreting these tests. For two-sample tests and N-way tests, nonparametric tests are also described. This book leads you step-by-step through each of the statistical tests with numerous screen shots, and you will see how to read and interpret all of the output generated by these tests. Experience with some basic statistical tests used to analyze medical data or classroom experience in biostatistics or statistics is required. Although the examples are related to the medical and biology fields, researchers in other fields such as psychology or education will find this book helpful. No programming experience is required. Loading data files into SAS University Edition? Click here for more information.
Statistical analysis is ubiquitous in modern medical research. Logistic regression, generalized linear models, random effects models, and Cox's regression all have become commonplace in the medical literature. But while statistical software such as SAS make routine application of these techniques possible, users who are not primarily statisticians must take care to correctly implement the various procedures and correctly interpret the output. Statistical Analysis of Medical Data Using SAS demonstrates how to use SAS to analyze medical data. Each chapter addresses a particular analysis method. The authors briefly describe each procedure, but focus on its SAS implementation and properly interpreting the output. The carefully designed presentation relegates the theoretical details to "Displays," so that the code and results can be explored without interruption. All of the code and data sets used in the book are available for download from either the SAS Web site or www.crcpress.com. Der and Everitt, authors of the best-selling Handbook of Statistical Analyses Using SAS, bring all of their considerable talent and experience to bear in this book. Step-by-step instructions, lucid explanations and clear examples combine to form an outstanding, self-contained guide--suitable for medical researchers and statisticians alike--to using SAS to analyze medical data.
This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.
Analysis in Nutrition Research: Principles of Statistical Methodology and Interpretation of the Results describes, in a comprehensive manner, the methodologies of quantitative analysis of data originating specifically from nutrition studies. The book summarizes various study designs in nutrition research, research hypotheses, the proper management of dietary data, and analytical methodologies, with a specific focus on how to interpret the results of any given study. In addition, it provides a comprehensive overview of the methodologies used in study design and the management and analysis of collected data, paying particular attention to all of the available, modern methodologies and techniques. Users will find an overview of the recent challenges and debates in the field of nutrition research that will define major research hypotheses for research in the next ten years. Nutrition scientists, researchers and undergraduate and postgraduate students will benefit from this thorough publication on the topic. - Provides a comprehensive presentation of the various study designs applied in nutrition research - Contains a parallel description of statistical methodologies used for each study design - Presents data management methodologies used specifically in nutrition research - Describes methodologies using both a theoretical and applied approach - Illustrates modern techniques in dietary pattern analysis - Summarizes current topics in the field of nutrition research that will define major research hypotheses for research in the next ten years
Biostatistics and Computer-Based Analysis of Health Data Using the R Software addresses the concept that many of the actions performed by statistical software comes back to the handling, manipulation, or even transformation of digital data. It is therefore of primary importance to understand how statistical data is displayed and how it can be exploited by software such as R. In this book, the authors explore basic and variable commands, sample comparisons, analysis of variance, epidemiological studies, and censored data. With proposed applications and examples of commands following each chapter, this book allows readers to apply advanced statistical concepts to their own data and software. - Features useful commands for describing a data table composed made up of quantitative and qualitative variables - Includes measures of association encountered in epidemiological studies, odds ratio, relative risk, and prevalence - Presents an analysis of censored data, the key main tests associated with the construction of a survival curve (log-rank test or Wilcoxon), and the Cox regression model
Complex Survey Data Analysis with SAS® is an invaluable resource for applied researchers analyzing data generated from a sample design involving any combination of stratification, clustering, unequal weights, or finite population correction factors. After clearly explaining how the presence of these features can invalidate the assumptions underlying most traditional statistical techniques, this book equips readers with the knowledge to confidently account for them during the estimation and inference process by employing the SURVEY family of SAS/STAT® procedures. The book offers comprehensive coverage of the most essential topics, including: Drawing random samples Descriptive statistics for continuous and categorical variables Fitting and interpreting linear and logistic regression models Survival analysis Domain estimation Replication variance estimation methods Weight adjustment and imputation methods for handling missing data The easy-to-follow examples are drawn from real-world survey data sets spanning multiple disciplines, all of which can be downloaded for free along with syntax files from the author’s website: http://mason.gmu.edu/~tlewis18/. While other books may touch on some of the same issues and nuances of complex survey data analysis, none features SAS exclusively and as exhaustively. Another unique aspect of this book is its abundance of handy workarounds for certain techniques not yet supported as of SAS Version 9.4, such as the ratio estimator for a total and the bootstrap for variance estimation. Taylor H. Lewis is a PhD graduate of the Joint Program in Survey Methodology at the University of Maryland, College Park, and an adjunct professor in the George Mason University Department of Statistics. An avid SAS user for 15 years, he is a SAS Certified Advanced programmer and a nationally recognized SAS educator who has produced dozens of papers and workshops illustrating how to efficiently and effectively conduct statistical analyses using SAS.
SAS Data Management for Public Health: An Introduction equips readers with the tools and knowledge they need to prepare public health data in SAS Data Management software for use in analysis. Highly accessible in nature, the book is specifically designed to help students who are new to SAS learn and master the system. The book is organized into 20 lessons. The opening lessons introduce SAS and provide tips and best practices for exploring data. Students are introduced to PROC MEANS, FREQ, UNIVARIATE, and PROC SGPLOT. They learn how to import data; merge, concatenate, and manage variables; perform data cleanup; and recode categorical and continuous variables. Specific lessons address comments, labels, and titles, formatting variables, conditional recoding, DO groups, arrays for recoding, and categorical data analysis. Closing lessons introduce stratified and subpopulation analysis, as well as logistic regression. The book includes an appendix to help students navigate and use SAS Studio. SAS Data Management for Public Health is an ideal resource for standalone courses in which SAS is taught or to complement any biostatistics or epidemiology course where students need to use SAS to analyze their data. Brianna Magnusson holds a Ph.D. in epidemiology and a M.P.H. from Virginia Commonwealth University. She is an associate professor in the Department of Public Health at Brigham Young University. Dr. Magnusson's research focuses on sexual and reproductive health with emphasis on factors influencing sexual decision-making. Caroline Stampfel holds an M.P.H. with a concentration in environmental epidemiology from the Yale School of Public Health. She serves as the director of programs for the Association of Maternal & Child Health Programs and leads a team of maternal and child health experts using data-driven, innovative approaches to improve the health and well-being of women, children, youth, families, and communities.
Explore biostatistics using JMP® in this refreshing introduction Presented in an easy-to-understand way, Introduction to Biostatistics with JMP® introduces undergraduate students in the biological sciences to the most commonly used (and misused) statistical methods that they will need to analyze their experimental data using JMP. It covers many of the basic topics in statistics using biological examples for exercises so that the student biologists can see the relevance to future work in the problems addressed. The book starts by teaching students how to become confident in executing the right analysis by thinking like a statistician then moves into the application of specific tests. Using the powerful capabilities of JMP, the book addresses problems requiring analysis by chi-square tests, t tests, ANOVA analysis, various regression models, DOE, and survival analysis. Topics of particular interest to the biological or health science field include odds ratios, relative risk, and survival analysis. The author uses an engaging, conversational tone to explain concepts and keep readers interested in learning more. The book aims to create bioscientists who can competently incorporate statistics into their investigative toolkits to solve biological research questions as they arise.
This book provides a hands-on introduction to Machine Learning (ML) from a multidisciplinary perspective that does not require a background in data science or computer science. It explains ML using simple language and a straightforward approach guided by real-world examples in areas such as health informatics, information technology, and business analytics. The book will help readers understand the various key algorithms, major software tools, and their applications. Moreover, through examples from the healthcare and business analytics fields, it demonstrates how and when ML can help them make better decisions in their disciplines. The book is chiefly intended for undergraduate and graduate students who are taking an introductory course in machine learning. It will also benefit data analysts and anyone interested in learning ML approaches.