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"The renewed threat of biological weapons highlights the importance of crafting policy responses informed by the rule of law. This book explores patterns in recent governance initiatives and advocates building a "global biosecurity concert" as a way to address the threats presented by biological weapons and infectious diseases in the early 21st century."--BOOK JACKET.
Biosecurity in the Age of Synthetic Biology is a comprehensive review of the biosecurity issues faced by the innovative and rapidly evolving field of synthetic biology. This is a meticulous review of the groundbreaking biotechnological advancements and the critical need for robust biosecurity measures. The book provides an in-depth examination of the ethical, legal, and societal dimensions shaping the future of synthetic biology research, in addition to a practical protocol for biosecurity risk assessment. This is the first book to offer a structured guideline for biosecurity risk assessment in synthetic biology. The author’s balanced view of the opportunities of synthetic biology and the inherent security risks reveals foundational concepts, cutting-edge applications, and international perspectives on biosecurity. This essential guide illuminates scientific and technological frontiers and advocates for a proactive approach ensuring the responsible development and use of synthetic biology. It is an indispensable resource for scientists, policymakers, and anyone interested in the intersection of biotechnology and biosecurity. Key Features: Provides instructions and examples for a biosecurity risk assessment. Includes detailed proposed outline for creating a Biosecurity Manual for broad adoption. Emphasizes the future challenges and opportunities. Offers insights on the role of artificial intelligence in synthetic biology and biosecurity.
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
Biosecurity in the Age of Synthetic Biology is a comprehensive review of the biosecurity issues faced by the innovative and rapidly evolving field of synthetic biology. It is an indispensable resource for scientists, policymakers, and anyone interested in the intersection of biotechnology and biosecurity.
Cover -- Contents -- List of Tables -- Acknowledgments -- Abbreviations -- Introduction -- PART I. PROTECT OR PROLIFERATE -- 1. Biodefense and the Security Dilemma -- 2. Vertical Proliferation and Threats from Within -- PART II. SECURE OR STIFLE -- 3. Laboratory Biosecurity -- 4. Export and Publication Controls -- PART III. REMEDY OR OVERKILL -- 5. Social Distancing and National Security -- 6. Border Security and Transnational Contagion -- PART IV. ATTENTION OR NEGLECT -- 7. The Agenda of Global Health Security -- 8. Public Health and Biodefense Priorities -- Conclusion -- Selected Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z -- About the Author
Based on a series of regional meetings on university campuses with officials from the national security community and academic research institutions, this report identifies specific actions that should be taken to maintain a thriving scientific research environment in an era of heightened security concerns. Actions include maintaining the open exchange of scientific information, fostering a productive environment for international scholars in the U.S., reexamining federal definitions of sensitive but unclassified research, and reviewing policies on deemed export controls. The federal government should establish a standing entity, preferably a Science and Security Commission, that would review policies regarding the exchange of information and the participation of foreign-born scientists and students in research.
Protecting and promoting health is inherently a political endeavor that requires a sophisticated understanding of the distribution and use of power. Yet while the global nature of health is widely recognized, its political nature is less well understood. In recent decades, the interdisciplinary field of global health politics has emerged to demonstrate the interconnections of health and core political topics, including foreign and security policy, trade, economics, and development. Today a growing body of scholarship examines how the global health landscape has both shaped and been shaped by political actors and structures. The Oxford Handbook of Global Health Politics provides an authoritative overview and assessment of research on this important and complicated subject. The volume is motivated by two arguments. First, health is not simply a technical subject, requiring evidence-based solutions to real-world problems, but an arena of political contestation where norms, values, and interests also compete and collide. Second, globalization has fundamentally changed the nature of health politics in terms of the ideas, interests, and institutions involved. The volume comprises more than 30 chapters by leading experts in global health and politics. Each chaper provides an overview of the state of the art on a given theoretical perspective, major actor, or global health issue. The Handbook offers both an excellent introduction to scholars new to the field and also an invaluable teaching and research resource for experts seeking to understand global health politics and its future directions.
The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
With our highly connected and interdependent world, the growing threat of infectious diseases and public health crisis has shed light on the requirement for global efforts to manage and combat highly pathogenic infectious diseases and other public health crisis on an unprecedented level. Such disease threats transcend borders. Reducing global threats posed by infectious disease outbreaks – whether naturally caused or resulting from a deliberate or accidental release – requires efforts that cross the disaster management pillars: mitigation, preparedness, response and recovery. This book addresses the issues of global health security along 4 themes: Emerging Threats; Mitigation, Preparedness, Response and Recovery; Exploring the Technology Landscape for Solutions; Leadership and Partnership. The authors of this volume highlight many of the challenges that confront our global security environment today. These range from politically induced disasters, to food insecurity, to zoonosis and terrorism. More optimistically, the authors also present some advances in technology that can help us combat these threats. Understanding the challenges that confront us and the tools we have to overcome them will allow us to face our future with confidence.