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This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give the reader a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. In addition to comprehensive coverage of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry.
Nano-scale materials are proving attractive for a new generation of devices, due to their unique properties. They are used to create fast-responding sensors with good sensitivity and selectivity for the detection of chemical species and biological agents. Nanosensors for Chemical and Biological Applications provides an overview of developments brought about by the application of nanotechnology for both chemical and biological sensor development. Part one addresses electrochemical nanosensors and their applications for enhanced biomedical sensing, including blood glucose and trace metal ion analysis. Part two goes on to discuss spectrographic nanosensors, with chapters on the use of nanoparticle sensors for biochemical and environmental sensing and other techniques for detecting nanoparticles in the environment. Nanosensors for Chemical and Biological Applications serves as a standard reference for R&D managers in a range of industrial sectors, including nanotechnology, electronics, biotechnology, magnetic and optical materials, and sensors technology, as well as researchers and academics with an interest in these fields. Reviews the range electrochemical nanosensors, including the use of carbon nanotubes, glucose nanosensors, chemiresistor sensors using metal oxides, and nanoparticles Discusses spectrographic nanosensors, such as surface-enhanced Raman scattering (SERS) nanoparticle sensors, the use of coated gold nanoparticles, and semiconductor quantum dots
This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give the reader a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, b
Biomedical nanosensors play a central role in the development of diagnostics and therapeutics for early detection and treatment of diseases. Bringing a nanoscale perspective to sensing is expected to allow interrogation of biological systems, detection of ultra small concentration of biomolecules, ions, and molecular interactions, exploration of cellular mechanisms, and integration of nanosensors into many other devices, including implantable devices. In this book we will specifically address nanomaterials, constituting nanoparticles, nanowires, and nanotubes of inorganic as well as polymeric composition of nano and micro scale dimensions as sensing and therapeutic agents since these constitute a major direction in nanomedicine. Selected technologies involving single molecule and single particle methods for tracking are also addressed.
Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles
Advances in Nanosensors for Biological and Environmental Analysis presents the current state-of-art in nanosensors for biological and environmental analysis, also covering commercial aspects. Broadly, the book provides detailed information on the emergence of different types of nanomaterials as transduction platforms used in the development of nanosensors. These include carbon nanotubes, graphene, 2-D transition metal dichalcogenides, conducting polymers and metal organic frameworks. Additional topics include sections on the way nanosensors have inspired new product development in various types of biological and environmental applications that are currently available and on the horizon. Features detailed information on various types of biological and environmental nanosensors Gives particular attention to the different categories of advanced functional interfaces, processes for their development, and application areas Includes the current state-of-the-art in terms of commercial aspects
The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these imaging particles can be designed to fulfill specific requirements for applications across different imaging modalities. It presents, for the first time, a comprehensive interdisciplinary overview of the impact nanoparticles have on biomedical imaging and is a common central resource for researchers and teachers.
Biological and chemical warfare agents, including viruses, bacteria, and explosive and radioactive compounds, can induce illness or death in humans, animals, and plants. Plasmonic nanosensors as detection tools of these agents offer significant advantages, including rapid detection, sensitivity, selectivity, and portability. This book explores novel and updated research on different types of plasmonic nanosensors for analysis of biological and chemical threat agents. It covers a brief theory of plasmonic nanosensors, summarizes the state-of-art in the molecular recognition of biological and chemical threat agents, and describes the application of various types of nanosensors in the detection of these threat agents. This book • Brings together recent academic research from an interdisciplinary approach including chemistry, biology, and nanotechnology. • Discusses current trends and developments. • Describes applications of a variety of different types of plasmonic nanosensors. • Explores outlooks and expectations for this technology. Showcasing the latest achievements in plasmonic nanosensors, this book will appeal to researchers in materials, chemical, and environmental engineering as well as chemistry interested in exploring the application of sensors to support environmental monitoring and global health.
Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.
Nanofabrication for Smart Nanosensor Applications addresses the design, manufacture and applications of a variety of nanomaterials for sensing applications. In particular, the book explores how nanofabrication techniques are used to create more efficient nanosensors, examines their major applications in biomedicine and environmental science, discusses the fundamentals of how nanosensors work, explores different nanofabrication techniques, and comments on toxicity and safety issues relating to the creation of nanosensors using certain nanomaterial classes. This book is an important resource for materials scientists and engineers who want to make materials selection decisions for the creation of new nansensor devices. Summarizes current research and applications of a variety of nanofabrication techniques for the creation of efficient sensing devices Provides readers with an understanding of surfaces and interfaces, a key challenge for those working on hybrid nanomaterials, carbon nanotubes, graphene, polymers and liquid crystal electro-optical imaging Discusses the variability and sight recognition of biopolymers, such as DNA molecules, which offer a wide range of opportunities for the self-organization of nanostructures into much more complex patterns