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This book is a review of past and current studies and future plans of the Laser Laboratory in Cincinnati and some of the contributions of laser research groups in other medical centers. Special thanks are due to the Directing Physicist of the Laser Labora tory, R. James Rockwell. Without his advice, constant supervision and corrections, this enthusiastic investigator would continue to upset even many more people than he has done already. The excuse, of course, is to stimulate much needed interest and controlled research and development of the laser for biology and medicine. The Associate Research Physicist, Ralph Schooley, has worked with many phases of laser research but especially in Q spoiling, Raman spectroscopy, and the almost alchemy of holography. Holography, as of now, provides many opportunities for Gumperson's Law, "If anything can go wrong, it will. " Sincere appreciation is expressed to the Surgeons in the Laser Labora tory, who have supplied clinical and investigative surgical supervision often under great difficulties, Dr. V. E. Siler and Dr. Bruce Henderson. We are grateful for help from the Directing Biologist of the Laser Labo ratory, Edmond Ritter, the Director of Laser Neurosurgery, Dr. Thomas Brown and the Professor of Neurosurgery, Dr. Robert McLaurin, for important and basic work in laser neurosurgery. Special thanks are given to Robert Meyer, who has given most of the treatments in careful and skillful fashion, and his associate, Robert Otten.
Lasers have a wide and growing range of applications in medicine. Lasers for Medical Applications summarises the wealth of recent research on the principles, technologies and application of lasers in diagnostics, therapy and surgery.Part one gives an overview of the use of lasers in medicine, key principles of lasers and radiation interactions with tissue. To understand the wide diversity and therefore the large possible choice of these devices for a specific diagnosis or treatment, the respective types of the laser (solid state, gas, dye, and semiconductor) are reviewed in part two. Part three describes diagnostic laser methods, for example optical coherence tomography, spectroscopy, optical biopsy, and time-resolved fluorescence polarization spectroscopy. Those methods help doctors to refine the scope of involvement of the particular body part or, for example, to specify the extent of a tumor. Part four concentrates on the therapeutic applications of laser radiation in particular branches of medicine, including ophthalmology, dermatology, cardiology, urology, gynecology, otorhinolaryngology (ORL), neurology, dentistry, orthopaedic surgery and cancer therapy, as well as laser coatings of implants. The final chapter includes the safety precautions with which the staff working with laser instruments must be familiar.With its distinguished editor and international team of contributors, this important book summarizes international achievements in the field of laser applications in medicine in the past 50 years. It provides a valuable contribution to laser medicine by outstanding experts in medicine and engineering. - Describes the interaction of laser light with tissue - Reviews every type of laser used in medicine: solid state, gas, dye and semiconductor - Describes the use of lasers for diagnostics
A careful review of the literature covering various aspects of applications of lasers in science and technology reveals that lasers are being applied very widely throughout the entire gamut of physical medicine. After surveying the current developments taking place in the field of medical applications of lasers, it was considered appropriate to bring together these efforts of international research scientists and experts into one volume. It is with this aim that the editors have prepared this volume which brings current research and recent developments to the attention of a wide spectrum of readership associated with hospitals, medical institutions and universities world wide, including also the medical instrument industry. Both teachers and students in the medical faculties will especially find this compendium quite useful. This book is comprised of eleven chapters. All of the important medical applications of lasers are featured. The editors have made every effort that individual chapters are self-contained and written by experts. Emphasis has been placed on straight and simple presentation of the subject matter so that even the new entrants into the field will find the book of value.
This text was designed for the physicians, nurses, technical personnel, and staff members of medical facilities using lasers for surgical, therapeutic, and diagnostic purposes. The objective is to provide an understanding of the potential health and safety hazards associated with the use of medical laser systems and the precautions needed to use them safely. To do this, it is necessary to have an awareness of applicable standargs and regula tions that apply to laser use. This book is not intended as a substitute for the American National Standards Institute (ANSI) Z-136. 3, "Safe Use of Lasers in Health Care Facilities," but to facilitate its implementation as well as the implementation of the many other related regulations and guidelines that are pertinent. These other regulations include the Medical Device Amendments to the Food and Drug Act, the Federal Laser Product Performance Standards issued under the Radiation Control for Health and Safety Act, and applicable regulations of the Occupational Safety and Health Administration (OSHA). The text is organized to provide first an overview of laser hazards, laser surgical applications, and laser biological effects. General safety control measures and safety standards are then presented. Because laser tech nology is rapidly evolving, these general guidelines will allow safe use of new laser systems as they become available. Finally, specific safety guide lines and precautions are provided for specialized laser applications in the different health care specialties.
Basic concepts such as the optical and thermal properties of tissue, the various types of tissue ablation, and optical breakdown and its related effects are treated in detail. Special attention is given to mathematical tools (Monte Carlo simulations, the Kubelka—Munk theory etc.) and approved techniques (photodynamic therapy, laser-induced interstitial thermotherapy etc.). The part on applications reviews clinically relevant methods in modern medicine using the latest references. The last chapter covers today’s standards of laser safety, with a careful selection of essential guidelines published by the Laser Institute of America. With numerous research photographs, illustrations, tables and comprehensive summaries.
Learn about the many biological and medical applications of ultrashort laser pulses. The authors highlight and explain how the briefness of these laser pulses permits the tracing of even the fastest processes in photo-active bio-systems. They also present a variety of applications that rely on the high peak intensity of ultrashort laser pulses. Easy-to-follow examples cover non-linear imaging techniques, optical tomography, and laser surgery.
Nanostructuring of materials is a task at the heart of many modern disciplines in mechanical engineering, as well as optics, electronics, and the life sciences. This book includes an introduction to the relevant nonlinear optical processes associated with very short laser pulses for the generation of structures far below the classical optical diffraction limit of about 200 nanometers as well as coverage of state-of-the-art technical and biomedical applications. These applications include silicon and glass wafer processing, production of nanowires, laser transfection and cell reprogramming, optical cleaning, surface treatments of implants, nanowires, 3D nanoprinting, STED lithography, friction modification, and integrated optics. The book highlights also the use of modern femtosecond laser microscopes and nanoscopes as novel nanoprocessing tools.
This comprehensive handbook gives a fully updated guide to lasers and laser technologies, including the complete range of their technical applications. This forth volume covers laser applications in the medical, metrology and communications fields. Key Features: • Offers a complete update of the original, bestselling work, including many brand-new chapters. • Deepens the introduction to fundamentals, from laser design and fabrication to host matrices for solid-state lasers, energy level diagrams, hosting materials, dopant energy levels, and lasers based on nonlinear effects. • Covers new laser types, including quantum cascade lasers, silicon-based lasers, titanium sapphire lasers, terahertz lasers, bismuth-doped fiber lasers, and diode-pumped alkali lasers. • Discusses the latest applications, e.g., lasers in microscopy, high-speed imaging, attosecond metrology, 3D printing, optical atomic clocks, time-resolved spectroscopy, polarization and profile measurements, pulse measurements, and laser-induced fluorescence detection. • Adds new sections on laser materials processing, laser spectroscopy, lasers in imaging, lasers in environmental sciences, and lasers in communications. This handbook is the ideal companion for scientists, engineers, and students working with lasers, including those in optics, electrical engineering, physics, chemistry, biomedicine, and other relevant areas.
Lasers in Medical Diagnosis and Therapy: Basics, applications and future prospects provides an overview on medical lasers and laser systems as well as laser applications in medical diagnosis and therapy. Since it was written by physicists, it focusses on the physics and underlying mechanisms of laser diagnosis and therapy.
The book describes the most advanced techniques for generating coherent light in the mid-infrared region of the spectrum. These techniques represent diverse areas of photonics and include heterojunction semiconductor lasers, quantum cascade lasers, tunable crystalline lasers, fiber lasers, Raman lasers, and optical parametric laser sources. Offering authoritative reviews by internationally recognized experts, the book provides a wealth of information on the essential principles and methods of the generation of coherent mid-infrared light and on some of its applications. The instructive nature of the book makes it an excellent text for physicists and practicing engineers who want to use mid-infrared laser sources in spectroscopy, medicine, remote sensing and other fields, and for researchers in various disciplines requiring a broad introduction to the subject.