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Published in 1973: A cardinal objective of this book is to present the current state-of-the-art technology of laminar airflow, as related to its biological use, in order to make the principles, the applications, and the testing methods readily understandable to medically and microbiologically oriented people.
First multi-year cumulation covers six years: 1965-70.
Germfree Research: Biological Effect of Gnotobiotic Environments is an account of the Proceedings of the Fourth International Symposium on Germfree Research. The volume comprises of 12 sections and 97 chapters. The first two sections serve as introduction to the status of germfree research as an approach to micro-ecology and gnotobiotic technology in clinical medicine. Another aspect discussed in the book deals with nutrition, metabolism, and microbiology. The last section provides a thorough and detailed discussion on gnotobiotic technology. Large part of the book focuses on gnotobiotic environments and its different aspects. Topics discussed include gnotobiotic environment on isolated patients and in dentistry and parasitology, as well as carcinogenesis in and physiological effects of gnotobiotic environments. The book is a very valuable source of information for many students and professionals in the fields of clinical medicine, biology, microbiology, nutritional science, and biochemistry.
First multi-year cumulation covers six years: 1965-70.
The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in diagnostic tests, drug delivery, and numerous other applications. More recently, evidence has become available that drug formulations with active components in a ?nely dispersed state may signi?cantly affect their functionality. Furthermore, with miniaturization of medical instrumentation, the size of the components is necess- ily reduced to colloid or even smaller range. This volume is a collection of several chapters dealing with diverse topics of colloids and surfaces relevant to medical applications. Thus, Siiman describes the use of optical properties of uniform colloidal particles as probes in ?ow cytometry. Giesche focuses on the preparations and properties of exceedingly uniform silica spheres for different uses, such as in chromatography. In modi?ed forms, silica p- ticles with incorporated dyes are employed in diagnostics and those combined with tiny magnetic entities in drug delivery.