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After nearly 20 years, the publication of this Second Edition of The Biology of the Laboratory Rabbit attests to its popularity within the scientific community as well as to the need to update an expanding database on the rabbit as a major species in laboratory investigation. The principal aim of this text is to provide a comprehensive and authoritative source of scientifically based information on a major laboratory animal species. The text continues to emphasize the normal biology as well as diseases of the European (domestic) rabbit, Orytolagus cuniculus, especially the New Zealand White breed, with occasional reference to other rabbit species (Sylvilagus sp.) and hares (Lepus sp.). New topics have been added to this second edition in response to changing trends in biomedical research and product testing as well as to suggestions from readers. New chapters included on: Anesthesia and analgesia Models in infectious disease research Models in ophthalmology and vision research Polyclonal antibody production Toxicity and safety testing Drug doses and clinical reference data
This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research.
The principal aim of this text is to provide a comprehensive source of scientifically based information on a major laboratory animal species - the rabbit. In this edition, a further aim is to update material to include an expanding data base obtained from laboratory use and investigation.
With laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting
First multi-year cumulation covers six years: 1965-70.
Each issue lists papers published during the preceding year.
The chapters which comprise this book were prepared as part of a medical text, Pathology of the Female Genital Tract, which is intended for the obstetrician, gynecologist, and medical pathologist. In that context, we were con cerned to bring out the importance of the study of tumors of the female reproductive tract of animals, both as show ing the variety of spontaneous neoplasms that might affect the tract and as providing tumors capable of experimental reproduction. These chapters are published separately, since they contain information which may appeal to a range of readers who might not necessarily wish to acquire the full medical text-for example, to veterinary and comparative pathologists, cancer research workers, research workers in gynecology, experimental pathologists and endocrinologists, and possibly to others using animals in experimental and pharmaceutical studies. The survey of spontaneous tumors of the female repro ductive tract is largely concerned with tumors of the ovaries and uterus of domesticated animals, but attention is also given to laboratory animals, wild animals, and animals in zoos. The spontaneous tumors are well worth studying, not only because of their obvious clinical impor tance to veterinarians, but also because they might provide a stimulus for epidemiologic, etiologic, biologic, and ther apeutic investigations that may elucidate some of the problems related to their counterparts in humans.