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The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude of different animals (including humans), plants and microbes, giving the reader a complete overview of recent developments and of the controversies currently surrounding the topic. Written by specialists from a variety of disciplines, this book is a valuable source of information for students and researchers interested in ageing and life history traits and populations.
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Much of our knowledge of stem cells has been inferred from studies of remarkable few species. The ability to manipulate stem cells in “model” organisms such as the mouse and a few other vertebrate species has driven our understanding of basic biology of stem cells. The power and efficiency of studying model organisms, however, comes at a cost since a few species, obviously, do not reflect nature ́s true diversity. Unfortunately, although all multicellular organisms seem to rely on stem cells, and although this seems to be a question of key importance for understanding the evolution of animal life, little is known about stem cells in early-branching taxa. “Stem Cells: From Hydra to Man” illustrates that there is more than human and mouse stem cells to learn from. Reflecting an enormous growth in the knowledge of stem cells in various organisms, the book presents the conceptual language and the nature of questions, as well as a summary of the advances in our understanding of stem cells from a comparative point of view that has resulted from the development of new technology and the development of novel model organisms over the past few decades. As such this book is largely a horizon analysis of a frontier rather than a retrospective. It presents an integrative approach to animal stem cells and covers the major contributions, tools and trends in a newly emerging field: comparative stem cell biology.
Biology of Hydra covers eight areas of Hydra biology, particularly, its behavior and ecology; polarity; gastrodermal and epidermal regeneration; differentiation of nervous elements; cell proliferation and morphogenesis; and mesoglea. This book describes, in particular, the various aspects of Hydra's behavior, not obvious in casual observation, as well as the animal's feeding and digestion. It also looks into the contribution of interstitial cells to the regenerative process in Hydra; the ultrastructural changes during dedifferentiation and redifferentiation in the regenerating, isolated gastrodermis; regeneration from isolated epidermal explants; and regeneration of a Hydra containing no interstitial cells from an isolated basal disc. Furthermore, the book explains the grafting of the gastrodermis of Hydra viridis to the epidermis of Hydra pseudoligactis, and the results of such agraft on two animals sectioned for histological study. It examines the role of the neoblast in regeneration and the ultrastructure of Hydra's nervous system. The book also explores Hydra's growth and the contribution of cell proliferation to net growth and maintenance of form.
Owing to their importance as primary producers of energy and nutrition, algae and cyanobacteria are found as symbiotic partners across diverse lineages of prokaryotic and eukaryotic kingdoms.Algal and Cyanobacteria Symbioses presents a compilation of recent, updated research in fields of diverse symbioses, including in marine, freshwater, and terrestrial habitats. It gives a comprehensive overview of algal and cyanobacteria symbioses, including reviews on their diversity and information on symbiotic specificity and stress tolerance. Also covered is a review of regulatory mechanisms in the communication between symbiotic partners.The highly interdisciplinary character of this book is demonstrated through the range of algae and cyanobacteria as energy-providing symbionts in organismal lineages which are discussed. It is a valuable source of knowledge for researchers, university lecturers, professors and students of biology and life sciences, specifically biochemistry, mycology, cell biology and plant-microbe interactions.
Coelenterate Biology: Reviews and New Perspectives highlights research areas in which coelenterates are exceptionally useful and interesting experimental animals. It outlines the state of knowledge in coelenterate research and draws attention to some of the challenging problems that are amenable for study. Coelenterates offer valuable material for many levels of inquiry—from the population and organismic to the cellular, subcellular, and molecular levels. They are especially attractive animals for studies in developmental biology and behavior. The book begins by discussing cnidarians histology, focusing on the light and electron microscopy of cnidarian tissues. There are separate chapters on the skeletal system of cnidarians; the morphology, functions, and chemistry of nematocytes; and a few aspects of the enormous subject of cnidarian development. The subsequent chapters deal with cnidarian neurobiology, behavior, locomotion, flotation, and dispersal; experimental studies on algae-cnidarian symbioses; and coelenterate bioluminescence. The book concludes with a discussion of the systems of coordination and nervous system of ctenophores.
This volume presents a broad panorama of the current status of research of invertebrate animals considered belonging to the phylum Cnidaria, such as hydra, jellyfish, sea anemone, and coral. In this book the Cnidarians are traced from the Earth’s primordial oceans, to their response to the warming and acidifying oceans. Due to the role of corals in the carbon and calcium cycles, various aspects of cnidarian calcification are discussed. The relation of the Cnidaria with Mankind is approached, in accordance with the Editors’ philosophy of bridging the artificial schism between science, arts and Humanities. Cnidarians' encounters with humans result in a broad spectrum of medical emergencies that are reviewed. The final section of the volume is devoted to the role of Hydra and Medusa in mythology and art.
"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.