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Containing nineteen chapters this comprehensive book is essential reading for every Chlamydia researcher.
New insights into one of the world's most common infectious diseases Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person's susceptibility to HIV and other STDs. Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control programs, genomics and pathogenicity, diagnosis, treatment, host immune responses, and the latest on the search for an effective vaccine. Also included are chapters on the impact of chlamydial infection on specific populations such as the lesbian, gay, bisexual and transgender community, and an update on the outbreak in Europe of the invasive chlamydial infection, lymphogranuloma venereum or LGV. This comprehensive publication is intended for clinicians, public health workers and scientists with interest in sexually transmitted diseases, medical microbiology, infectious diseases and clinical research.
Chlamydiae are a group of obligate intracellular microorganisms with a homogeneous group-specific antigenic structure, and a unique mode of development. The infections caused by them are unprecedented and wide-spread throughout the world, including a broad range of hosts among domestic and animal species and humans, and a variety of clinical manifestations. The uniqueness of chlamydia pathology consists mainly in the fact that the agents of the individual diseases are so close in their biological properties that they are represented only by the single genus Chlamydia, which includes all currently recognized species.Although chlamydiae and chlamydial infections were discovered a long time ago, they are still under-researched and relatively unknown to broad circles of microbiologists, virologists, epidemiologists and clinicians. A number of issues relating to molecular biology, pathogenesis, mechanisms of Chlamydia development and their interactions with cells, as well as their genetic conditioning and regulation, remain unclear. The same is true for ambiguities, problems and contradictions related to epidemiology, diagnostic approaches, immunity and vaccines. Based on scientific facts and the analysis of literature, and the experience of the author, Chlamydiae and Chlamydial Infections attempts to shed light on the cited problems, in terms of modern microbiology, cell biology and molecular biology. The scientific topics discussed include:• Biological, morphological and antigenic properties of Chlamydia spp• Genes, genomic structure and genetic regulations• Conventional diagnostic methods and examinations• Detection and differentiation of Chlamydia organisms by DNA detection systems• Clinical forms and manifestations and drug therapy• Pathology• Epidemiological peculiarities of Chlamydia ─ induced diseases in animals and humans• Immunity and vaccines
First Published in 1988, this book offers a full, comprehensive guide into microbiology of Chlamydia and its relationship with our bodies. Carefully compiled and filled with a vast repertoire of notes, pictures, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.
The Atlas of Sexually Transmitted Diseases and AIDS, 4th Edition, by Drs. Stephen A. Morse, King K. Holmes, Adele A. Moreland, MD, and Ronald C. Ballard, provides you with an exclusive gallery of STD and AIDS images so you can better diagnose and treat these diseases. Approximately 1,100 unique images – most in full color and 30% new to this edition – depict the clinical signs associated with each type of infection. You’ll also find expert guidance on new vaccines, screening techniques, treatment guidelines, and best practices in the field. Get expert advice on the tests available to reach a definitive diagnosis and review therapeutic options, treatment guidelines, prevention strategies, and management of complications. Access appendices on the selection and evaluation of diagnostic tests, quality control, and test technologies. Effectively diagnose all types of STDs and HIV/AIDS with approximately 1,100 images—most in full color and more than 30% new to this edition―that depict the epidemiology as well as the clinical manifestations of these diseases. Effectively utilize new vaccines for HPV and Hepatitis B, new screening tests for Chlamydia, new drugs under development, new treatment guidelines and best practices in HIV screening, and much more.
Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.
Multidisciplinary collection of essays on the relationship of infertility and the "historic" STIs--gonorrhea, chlamydia, and syphilis--producing surprising new insights in studies from across the globe and spanning millennia.
Comprehensively explores sexually transmitted diseases, from epidemiology, causative pathogens, clinical impact, and immunology, to management strategies utilizing new strategies of genomics and next-generation diagnostic tools Sexually transmitted infections (STI) are very common worldwide. More than 20 different STIs have been identified, and about 19 million men and women are infected each year in the United States alone. This book looks at the complete picture of common STIs— how they form, evolve, and transmit, as well as how they can be treated and managed with modern techniques, medicines, and tools. Diagnostics to Pathogenomics of Sexually Transmitted Infections runs the spectrum of discussion ranging from introduction of causative pathogen, their pathogenesis to epidemiology, immunology, to anatomy and physiology of human genitalia and management strategies. The book offers in-depth chapter coverage on effect of probiotics on reproductive health; mucosal immunity in sexually transmitted infections; the role of circumcision in preventing STIs; Human Immunodeficiency Virus (HIV); genital herpes; molluscum contagiosum; genital warts; chlaymydia trachomatis; donovanosis; gonorrhoea; treponematoses; genital mycoplasms; bacterial vaginosis; vulvovaginal candidiasis; chlaymydia; scabies; chancroid, yeast infections; and more. Comprehensively compiles most of the major sexually transmitted infections Presents updated information on clinical aspects of sexually transmitted infections Examines the priorities in pathogenesis of human sexually transmitted infections and discusses new strategies of genomics and next-generation diagnostic tools used for detection of such pathogens Explores the future of rapid molecular diagnostic techniques and the challenges posed in the diagnosis of human STIs Includes bench to bedside content that will appeal to both basic and clinical researchers By offering the latest knowledge about recent advances in sexually transmitted infections in an interdisciplinary fashion, Diagnostics to Pathogenomics of Sexually Transmitted Infections is the perfect book for virologists, microbiologists, infectious disease experts, vaccinologists, biomedical researchers, clinicians, pharmacologists, and public health specialists.
The Planctomycetes, Verrucomicrobia, Chlamydiae (PVC) and related phyla have recently emerged as fascinating subjects for research in evolutionary cell biology, ecology, biotechnology, evolution and human health. This interest is prompted by particular characteristics observed in the PVC superphylum that are otherwise rarely observed in bacteria but are however still poorly described or understood, such as the presence of a complex endomembrane system, or compacted DNA throughout most of the cell cycle. Therefore, the members of the PVC superphylum represent an excellent example of the value of studying bacteria other than ‘classical’ models.