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BioCoder is a quarterly newsletter for DIYbio, synthetic bio, and anything related. You’ll discover: Articles about interesting projects and experiments, such as the glowing plant Articles about tools, both those you buy and those you build Visits to DIYbio laboratories Profiles of key people in the community Announcements of events and other items of interest Safety pointers and tips about good laboratory practice Anything that’s interesting or useful: you tell us! And BioCoder is free (for the time being), unless you want a dead-tree version. We’d like BioCoder to become self supporting (maybe even profitable), but we’ll worry about that after we’ve got a few issues under our belt. If you’d like to contribute, send email to [email protected]. Tell us what you’d like to do, and we’ll get you started.
BioCoder is a quarterly newsletter for DIYbio, synthetic bio, and anything related. You'll discover: Articles about interesting projects and experiments, such as the glowing plant Articles about tools, both those you buy and those you build Visits to DIYbio laboratories Profiles of key people in the community Announcements of events and other items of interest Safety pointers and tips about good laboratory practice Anything that's interesting or useful: you tell us! And BioCoder is free (for the time being), unless you want a dead-tree version. We'd like BioCoder to become self supporting (maybe even profitable), but we'll worry about that after we've got a few issues under our belt. If you'd like to contribute, send email to [email protected]. Tell us what you'd like to do, and we'll get you started.
The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.
Multispectral signatures matching those of the Pleiades’ spacecraft have been detected on three different Pacific islands. Ciara and her friends journey to these locations only to discover that they are interconnected by a wormhole, serving as a portal to Earth’s twin planet. However, this connection has become unstable, generating high-intensity gravity fields that result in space-time distortions. Ciara’s life is threatened when she is transported back in time to be captured by the Taniwha, a supernatural being from Māori mythology. Ciara’s visions of her ancestor, 18th-century naval officer William Hartley, shed light on her own predicament. However, Hartley has been wrongfully accused of murdering Royal Society artist, Elliot Loundes. Unless the timeline can be restored, Ciara’s existence will come to an abrupt end. Can she and her friends outsmart the Taniwha, rescue her ancestor from the gallows, and stabilize the wormhole? The task will demand a sacrifice that few would be willing to make.
Ciara Alinec has visions of past and future events due to a unique sequence of DNA from an unknown source. Unexpectedly, her aunt and uncle move to South Korea, and Ciara finds herself attending a private international academy on Jeju Island. The school is the brainchild of a biotech billionaire, Dr Sanjung Kim, who has assembled the most gifted students globally. With guidance from the social counsellor, James Fernley, Ciara learns to harness her abilities. Ciara is critical to Dr Kim’s plan to discover a race of supernatural beings from Māori mythology, a species with technology far in advance of humans. Through her visions of an 18th-century naval officer called William Hartley, Ciara experiences his life. But are her actions to discover the location of these beings preordained? Accompanied by her friends, Ciara travels to New Zealand to unravel the mystery, only to trigger a series of events that may destroy humanity.
When Ciara arrives on Alcyone, the Taniwha initiate an audacious assault aimed at her capture. They have amassed a formidable invasion force but need Ciara’s singular ability to navigate the wormhole. Narrowly evading capture, she returns to Earth, only to find herself the quarry of a secretive faction known as ‘Ananke’. Accused of smuggling weapons of mass destruction into South Korea, she is confined within the stark walls of a police cell. While there, Ciara has a vision of Scottie on the precipice of death at Kealakekua Bay on the day of James Cook’s demise. Through her visions of naval officer William Hartley, Ciara learns that Ananke agents are Taniwha with human hosts. Over the centuries, they have shifted from person to person, infiltrating governments and the world’s most influential organisations. When a startling discovery forces Ciara to return to Alcyone, she faces the challenge of mastering time travel to retrieve a critical artefact. Can she elude the clutches of Ananke, save Scottie’s life, and halt the Taniwha invasion?
This book features extended versions of selected papers that were presented and discussed at the 8th International Doctoral Symposium on Applied Computation and Security Systems (ACSS 2021), held in Kolkata, India, on April 9–10, 2021. Organized by the Departments of Computer Science & Engineering and A. K. Choudhury School of Information Technology at the University of Calcutta, the symposium’s international partners were Ca' Foscari University of Venice, Italy, and Bialystok University of Technology, Poland. The topics covered include biometrics, image processing, pattern recognition, algorithms, cloud computing, wireless sensor networks, and security systems, reflecting the various symposium sessions.
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.
Human Choice and Computers: Issues of Choice and Quality of Life in the Information Society presents different views about how terrorist actions are influencing political and social discussions and decisions, and it covers questions related to legitimacy and power in the Information Society. Ethical principles are important guidelines for responsible behavior of IT professionals. But even under strong external pressure, long ranging aspects such as education and the roles of developing countries in the Information Society are important to discuss, especially to enable all to actively participate in information processes.